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Guest house holiday rentals in Doña Ana County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Doña Ana County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
Guest house in Las Cruces
4.95 out of 5 average rating, 196 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Top guest favourite
A spacious entryway leads into a cozy living area featuring a green couch and a round wooden coffee table. Light-colored flooring and soft lighting create a bright ambiance. A small dining area with two black stools is visible beside a wooden countertop, adorned with potted plants.
Guest house in El Paso
4.97 out of 5 average rating, 331 reviews

Cozy Modern Casita-Studio!

Perfectly located in Central El Paso! Found near the Franklin Mountain range, Downtown El Paso, great restaurants, sporting arenas, multiple hospitals, Fort Bliss Army base, and much more! Conveniently near multiple freeways for quick access to surrounding locations! -Newly renovated -Equipped with new modern appliances -Washer and dryer -Refrigerated air and heating -Comfortable queen bed -Sleeper sofa to accommodate a 3rd guest or children -Pack n’ play available for extra fee by request

Top guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guest house in Las Cruces
4.96 out of 5 average rating, 112 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Top guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guest house in Las Cruces
4.98 out of 5 average rating, 152 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Top guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guest house in Las Cruces
5 out of 5 average rating, 269 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guest house in Mesilla
4.97 out of 5 average rating, 379 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Guest favourite
A tranquil sleeping area features a spacious bed adorned with decorative pillows and a handwoven wall hanging above. Soft lighting from an ornate chandelier complements the adobe walls, while a rustic table and chairs anchor the inviting space.
Guest house in Las Cruces
4.97 out of 5 average rating, 327 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Top guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guest house in Las Cruces
4.97 out of 5 average rating, 318 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guest house in El Paso
4.9 out of 5 average rating, 166 reviews

Private studio w/ scenic view near downtown

Relax in this cozy studio apartment attached to a beautiful home with access to hot tub and abundant scenic views. Nestled in the Franklin mountains, you can enjoy hiking trails and the famous Scenic Drive. A 2-minute drive to downtown you will find authentic cuisine and nightlife. Close to UTEP, hospitals and international bridge, this property is located in the heart of the city. Free parking, Wi-Fi, and coffee bar with many selections!

Top guest favourite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guest house in Las Cruces
4.99 out of 5 average rating, 188 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guest house in Las Cruces
4.99 out of 5 average rating, 172 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Guest favourite
The exterior of the casita features a contemporary design with white stucco walls and a distinctive terra-cotta tiled roof. Landscaping includes small shrubs and gravel, with a driveway leading to a one-car garage. The entrance is marked by a decorative light fixture flanking the door.
Guest house in Las Cruces
4.92 out of 5 average rating, 150 reviews

Lovely Casita Suite (No Cleaning fee)

Unique place has a style all its own. New Casita in a new area close to professional Golf Course located at the foothills of the majestic organ mountains. Private entrance, kitchenette, living area that has a new sofa sleeper which can sleep up to 2 people. Has a private bedroom and private bathroom. Easy access to main highway that leads to shopping and restaurants.

Popular amenities for guest house rentals in Doña Ana County