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Guest house holiday rentals in Doña Ana County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Doña Ana County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
The kitchen features white cabinetry with glass-fronted doors, a granite countertop, and stainless steel appliances. A decorative rug lies on the floor, while plants and artwork add touches of color. Ample natural light illuminates the space, creating a welcoming atmosphere for meal preparation.
Guest house in Las Cruces
4.95 out of 5 average rating, 110 reviews

Relax in the ❤️ of Old Mesilla. Close to plaza.

Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Guest favourite
Guest house in Las Cruces
4.95 out of 5 average rating, 168 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Top guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guest house in Las Cruces
4.99 out of 5 average rating, 218 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Top guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guest house in Las Cruces
5 out of 5 average rating, 289 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guest house in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guest house in Las Cruces
4.97 out of 5 average rating, 380 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guest house in El Paso
4.92 out of 5 average rating, 225 reviews

Private studio w/ scenic view near downtown

Relax in this cozy studio apartment attached to a beautiful home with access to hot tub and abundant scenic views. Nestled in the Franklin mountains, you can enjoy hiking trails and the famous Scenic Drive. A 2-minute drive to downtown you will find authentic cuisine and nightlife. Close to UTEP, hospitals and international bridge, this property is located in the heart of the city. Free parking, Wi-Fi, and coffee bar with many selections!

Top guest favourite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guest house in Las Cruces
4.99 out of 5 average rating, 220 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guest house in Las Cruces
4.99 out of 5 average rating, 249 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top guest favourite
The historic Old Spanish Mission building is illuminated against a twilight sky, showcasing its unique architectural features. The white stucco exterior is complemented by natural landscaping and a gravel driveway, inviting guests to explore the surrounding area.
Guest house in Hatch
4.95 out of 5 average rating, 111 reviews

Historic Mission - Priest's Quarters-1BR, 1Bath

Located near Hatch, New Mexico...the Chile Capital of the World...is an Old Spanish Mission built in 1860. St Francis de Sales stopped being an active church in 1963, but still retains its special flavor unique to southwest New Mexico. Come stay in the Colorado Room located within the Rectory (priest's quarters) on the property. Everyone enjoys a one-of-kind experience here. You will, too.

Top guest favourite
A warm sleeping area features a queen bed with a neutral quilt and accent pillows. Two bedside lamps illuminate the space with soft light. The ceiling showcases rustic wooden beams, while a framed artwork hangs above the bed, complemented by a textured area rug beneath.
Guest house in Las Cruces
4.95 out of 5 average rating, 201 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Top guest favourite
The exterior of a single-story casita is shown, featuring a light pink stucco facade and a red-tile roof. A gated entrance is visible, along with a small lawn and a concrete walkway leading to the door. A garage door is also seen on the left.
Guest house in Las Cruces
4.96 out of 5 average rating, 1,163 reviews

Cozy Casita with Patio

Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi

Popular amenities for guest house rentals in Doña Ana County