
House holiday rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
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Luxury Surfhouse 5Min to Pismo Walk to Restaurants
Modern open-air retreat, minutes from Pismo Beach and walking distance to restaurants, shops, coffee and entertainment. Bright and spacious, our Airbnb was carefully designed for comfort and connection, wrapped in a coastal luxury vibe. Families love the surf lounge, games, fire pit, and beach gear. Our one-of-a-kind Airbnb is fully stocked with everything you need, making your stay relaxing and stress-free. With a short drive to SLO or Avila, your next unforgettable coastal getaway begins here.

1879 Victorian in Central Coast Wine Country
Lovely private 1879 Victorian built by Lompoc founder W.W. Broughton - with fully stocked kitchen, living room/ dining room, laundry room, full bathroom, back yard (lawn mowed Tuesdays, watering/ gardening is done generally in the mornings, cable TV, internet, set in spacious, beautifully manicured Victorian Gardens. Reservation includes two bedrooms with queen beds. Note: Entrance stairs may be difficult for those with limitations. No pets. Two triplexes with six renters are also on property.

Beach-themed farmhouse with indoor fireplace
As 13-time Superhosts- we welcome you to the perfect place to relax & unwind after your day. This stylish and spacious home offers a sunny deck, surrounded by trees for sunbathing or watching the sunset. The huge 2nd bdrm is a great place for reading in our hammock chair or for a quiet work space. Downstairs the fully equipped kitchen has everything you need for cooking meals. Outdoor patio is a nice place to bbq & relax as you listen to the hawks, owls, & other birds in this country setting.

Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Wine cellar House
Welcome to Bodega House! We can’t wait to host you at our charming 1920s farmhouse in Los Alamos. Please note that we’re currently making some updates to the house. At this time, there is one queen bed available, and the second bedroom has been arranged as a lounge. The space comfortably accommodates two guests, with a sofa bed available — perfect for a child or extra guest. Our wine and beer garden, Bodega, is next door. Stop by and relax with a glass of wine during Bodega’s business hours.

Gateway to SLO County with Pickleball & Game Room
Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

Shore To Please Beach House Oceano Pismo Avila SLO
A complete downstairs beach house with a kitchen, living room, relaxing bedroom, smart TVs, backyard, BBQ, bikes & a game room- Unlimited Vehicle Pass to Dunes - 1 mile to beach - 3/4 mile to Enormous kids park - Restaurants within walking distance - Netflix - Boll & Branch bedding - 5-8 minute drive to Pismo, Grover Beach, & Arroyo Grande - Near Avila beach, Shell beach & San Luis Obispo - 20 min drive to Cayucos & Morro Bay. DropMyPin for complete amenities & pictures.

Pleasant hills, king suite, EV Charger
Come relax and enjoy our peaceful home and outdoor spaces. We are located halfway between Los Angeles and San Francisco. Here you can experience the beautiful Central Coast including wineries, Beaches, Cal Poly and golf courses. We are located in a quiet neighborhood adjacent to an organic blackberry farm. Easy access to the 101 Freeway, where you can easily visit Santa Barbara or Paso Robles wine regions. Our home is FULLY Air Conditioned for your comfort.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views
Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Spacious Slo Studio: AirBnB Dream
Solo or couple travelers this place is for you and what Air BNB was originally all about. Unique, friendly space that has taken on energy from all the travelers. Check in 3pm. Peep reviews, take it from patrons! BUSINESS LICENSE #: Zero Zero Zero One Six One Zero Eight Two Zero One Nine
Popular amenities for house rentals in Guadalupe
House rentals with a pool

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious 4bd Home w/ Pool, Spa + Pet Friendly!

San Luis Obispo House With Pool And Hot Tub

Fairway to Heaven

Getaway at the Highlands+Heated Pool+Hot Tub

Central Coast close to wineries and beaches

Historic 1895 Edna Railhouse with Heated Pool

The Bridle Flat
Weekly house rentals

The Quailhouse on Ranch near Avila Beach

Pelican Cove Vacation Rental at the Back Bay

Western Village

Pacific Coast Highway Milkhouse

Serenity On Serrano

Back Bay Getaway - Dog Friendly - Home in Los Osos

Cozy Studio Close to Downtown SLO

Perfect Central Coast Getaway Retreat Close to All
Private house rentals

Baywood Park Garden Cottage

Cozy Plant-Filled Loft in Orcutt

1 Block from Beach with long driveway for parking

Elegant retreat on the Central Coast

Family Home with Playground close to Beach

Coastal Retreat - Sauna, Fire Pit & Outdoor Lounge

Coastal cottage in Pismo beach

2735 Nokomis
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Northern California Holiday rentals
- Channel Islands of California Holiday rentals
- La Joya Holiday rentals
- San Francisco Bay Area Holiday rentals
- San Diego Holiday rentals
- San Francisco Holiday rentals
- Gold Country Holiday rentals
- Central California Holiday rentals
- San Francisco Peninsula Holiday rentals
- Cayucos Beach
- Captain State Beach
- Montaña de Oro State Park
- Natalie's Cove
- Arroyo Quemada Beach
- Gaviota Beach
- B & E Vineyard & Winery
- Cayucos State Beach
- Morro Strand State Beach
- Refugio Beach
- Mission San Luis Obispo de Tolosa
- Morro Rock Beach
- Dairy Creek Golf Course
- Seal Beach
- Morro Bay Golf Course
- Pirates Cove Beach
- Point Sal State Beach
- Sand Dollars
- Baywood Park Beach
- Olde Port Beach
- Bianchi Winery
- Pismo State Beach
- Spooner's Cove
- Bovino Vineyards




