
House holiday rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
Guests agree: these houses are highly rated for location, cleanliness and more.

Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Perfect Central Coast Getaway Retreat Close to All
Stay in this freshly painted and newly furnished beach house. As soon as you walk through the door you'll feel relaxed and at home here. This spacious 2 bdrm and 1.5 bath house sleeps 6. Both of the bdrms have comfortable king size beds with 600 thread count sheets. The kitchen is ready for cooking and includes a Keurig. The backyard is the perfect place to hang out around the firepit and grill after a day of exploring the Central Coast. Walking distance to the Oceano Dunes.

Wine cellar House
Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Beach home near golf, wineries, dunes & Vandenburg
This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

Beach-themed country home w/ backyard tiki hut
As 23-time Superhosts we welcome you! This adorable home is perfect for couples or families. Enjoy the relaxation of country living; yet just 15 mins from the beaches. We have included everything we could think of for you to have a stress-free and fun vacation; the softest of beds & linens, a fully-stocked kitchen, games, fire-pit , satellite tv/smart tv and beach gear.

Garden Room Central Coast Wine Country
Lovely private one bedroom with private entrance and contactless check-in, private bath and kitchenette, in one of the original Victorian homes of Lompoc built in 1879. The renovated landmark is set in a spacious, quiet, beautifully manicured Victorian Gardens in the heart of Central Coast Wine Country! (No pets.) Two triplexes with six renters are also on property.

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views
Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Luxury Village Home
Enjoy a stylish experience at this centrally-located home in the village of Arroyo Grande. This pet friendly home is close to the village, beach, and wineries. With luxury Parachute linens throughout, a kid area, and a sprawling outdoor patio with BBQ pit, this home is sure to impress. Please see our professional photos!

Spacious Slo Studio: AirBnB Dream
Solo or couple travelers this place is for you and what Air BNB was originally all about. Unique, friendly space that has taken on energy from all the travelers. Check in 3pm. Peep reviews, take it from patrons! BUSINESS LICENSE #: Zero Zero Zero One Six One Zero Eight Two Zero One Nine

Beach, Wine Country, & Golf adjacent home for 8
Full home privacy, with a backyard to properly relax in after a day spent exploring the beautiful Central Coast. Enjoy the quiet of Nipomo in this country living style home. Pour some wine, light up the fire pit, toss some horseshoes, and kick back at Tejas Place!
Popular amenities for house rentals in Guadalupe
House rentals with a pool

Indoor Private Pool Close to the Beach

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

San Luis Obispo House With Pool And Hot Tub

Getaway at the Highlands+Heated Pool+Hot Tub

Hot tub, heated pool (82 degrees), gas fire pit

FairView Lavender Estate
Weekly house rentals

Bayview Getaway

Baywood Park Garden Cottage

Pelican Cove Vacation Rental at the Back Bay

Blue Wave of Avila

In the Heart of Los Olivos

Back Bay Getaway - Dog Friendly - Home in Los Osos

Amazing Grace-Morro Bay Golf course w/Water Views!

Cozy Studio Close to Downtown SLO
Private house rentals

Chelsea’s on Victoria

Cozy Beach Bungalow in Cayucos!

1 Block from Beach with long driveway for parking

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Luxury Surfhouse 5Min to Pismo Walk to Restaurants

Ocean's Calling Cottage Sleeps five. 2 bed/2bath

Herter House Beach Retreat

Luxe Hideaway: Prvt Patio BBQ Winery, 20 min-Beach
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Northern California Holiday rentals
- Channel Islands of California Holiday rentals
- San Francisco Bay Area Holiday rentals
- San Diego Holiday rentals
- San Francisco Holiday rentals
- Gold Country Holiday rentals
- Central California Holiday rentals
- San Francisco Peninsula Holiday rentals
- Palm Springs Holiday rentals
- Cayucos Beach
- El Capitán State Beach
- Montaña de Oro State Park
- Natalie's Cove
- Arroyo Quemada Beach
- Gaviota Beach
- B & E Vineyard & Winery
- Morro Strand State Beach
- Refugio Beach
- Cayucos State Beach
- Seal Beach
- Mission San Luis Obispo de Tolosa
- Dairy Creek Golf Course
- Morro Rock Beach
- Pirates Cove Beach
- Morro Bay Golf Course
- Sand Dollars
- Olde Port Beach
- Spooner's Cove
- Point Sal State Beach
- Bovino Vineyards
- Bianchi Winery
- Baywood Park Beach
- Allegretto Wines




