House holiday rentals in Guadalupe

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe

Guests agree: these houses are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1
Guest favourite
A sunset sky filled with vibrant colors casts a warm glow over the country house. The exterior is highlighted by large windows and a welcoming entrance. The driveway leads towards the home, bordered by manicured landscaping, set against a backdrop of rolling hills.
Home in Arroyo Grande
4.83 out of 5 average rating, 285 reviews

Coastal Getaway, Country House, near 101 FWY

Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Top guest favourite
A large outdoor patio area features a covered gazebo with seating and a paved surface. The surrounding landscape includes greenery and distant hills, providing a serene backdrop. The space is designed for relaxation and outdoor gatherings.
Home in Arroyo Grande
5 out of 5 average rating, 146 reviews

Hillside view with hot tub too

This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.

Guest favourite
A modern living area features a large, flat-screen TV against a white wall. A surfboard is mounted beside a fireplace, and a round glass-top coffee table is set on a blue-patterned area rug. Natural light filters through sheer curtains.
Home in Oceano
4.95 out of 5 average rating, 168 reviews

Casa Del Mar

Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Guest favourite
The exterior of the beach house is shown, featuring a two-story white structure with a balcony. A patio area with a blue umbrella and outdoor seating is visible. Colorful flowers enhance the landscaping, while the sky appears clear with soft clouds.
Home in Oceano
4.89 out of 5 average rating, 147 reviews

Perfect Central Coast Getaway Retreat Close to All

Stay in this freshly painted and newly furnished beach house. As soon as you walk through the door you'll feel relaxed and at home here. This spacious 2 bdrm and 1.5 bath house sleeps 6. Both of the bdrms have comfortable king size beds with 600 thread count sheets. The kitchen is ready for cooking and includes a Keurig. The backyard is the perfect place to hang out around the firepit and grill after a day of exploring the Central Coast. Walking distance to the Oceano Dunes.

Top guest favourite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 353 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Top guest favourite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 271 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Guest favourite
The open living area features wood-look flooring, a ceiling fan, and large windows allowing natural light. A comfortable seating arrangement includes a dark sofa and chairs, alongside a wooden coffee table. Decorative plants and fresh flowers add a touch of greenery to the space.
Home in Oceano
4.95 out of 5 average rating, 136 reviews

Spacious Whole Residence w/ Bikes--Close to Beach!

Single story 3bd/2ba home in a quiet informal neighborhood ~ 1.5 miles (30 min walk/10 min bike ride) to the beach. Full Kitchen, Washer/Dryer, Indoor Grill, Outdoor Grill, Waffle Iron, Pressure Cooker/Slow Cooker, Dutch Oven, Mixer, Blender, Bicycles w/Locks & Helmets, Wifi, Smart Tv's (in every bedroom and in the living room) and a Stand/Sit Desk with Computer, Printer/Fax/Scanner, plus other amenities...

Guest favourite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.94 out of 5 average rating, 233 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Guest favourite
A modern two-story home is depicted, showcasing a light-colored exterior with dark trim. The front yard features low-maintenance landscaping with desert plants. A driveway leads to the garage, and neighboring homes are visible in a suburban setting under a clear blue sky.
Home in Guadalupe
4.84 out of 5 average rating, 238 reviews

Beach home near golf, wineries, dunes & Vandenburg

This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

Guest favourite
A spacious backyard is presented, featuring a lush green lawn and a winding pathway that leads to a rustic tiki hut with a firepit. Surrounding trees provide shade, and flower beds add color to the landscape.
Home in Arroyo Grande
4.89 out of 5 average rating, 621 reviews

Beach-themed country home w/ backyard tiki hut

As 23-time Superhosts we welcome you! This adorable home is perfect for couples or families. Enjoy the relaxation of country living; yet just 15 mins from the beaches. We have included everything we could think of for you to have a stress-free and fun vacation; the softest of beds & linens, a fully-stocked kitchen, games, fire-pit , satellite tv/smart tv and beach gear.

Guest favourite
The exterior of the historic Victorian home features a vibrant bay window adorned with red flowers. Lush greenery and manicured hedges surround the building, creating a charming and inviting setting. Sunlight filters through the foliage, enhancing the tranquil ambiance of the garden.
Home in Lompoc
4.92 out of 5 average rating, 779 reviews

Garden Room Central Coast Wine Country

Lovely private one bedroom with private entrance and contactless check-in, private bath and kitchenette, in one of the original Victorian homes of Lompoc built in 1879. The renovated landmark is set in a spacious, quiet, beautifully manicured Victorian Gardens in the heart of Central Coast Wine Country! (No pets.) Two triplexes with six renters are also on property.

Top guest favourite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 127 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Popular amenities for house rentals in Guadalupe