
House holiday rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
Guests agree: these houses are highly rated for location, cleanliness and more.

1879 Victorian in Central Coast Wine Country
Lovely private 1879 Victorian built by Lompoc founder W.W. Broughton - with fully stocked kitchen, living room/ dining room, laundry room, full bathroom, back yard (lawn mowed Tuesdays, watering/ gardening is done generally in the mornings, cable TV, internet, set in spacious, beautifully manicured Victorian Gardens. Reservation includes two bedrooms with queen beds. Note: Entrance stairs may be difficult for those with limitations. No pets. Two triplexes with six renters are also on property.

Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Ocean Breeze Escape | Sunny Beach House
Have fun with the whole family at this stylish place. This is an amazing brand new construction home in the heart of Grover Beach. (STR0195) - 5 min walk to beach - 3 min walk to coffee shops and restaurants - front deck with fireplace - EV charging for your electric vehicle for 25$ fee per night - fully equipped kitchen with dinner wares and, pots and pans - dual coffee maker with both drip and keurig - outdoor shower for after beach rinse off - 2 bedrooms with king beds in both

Wine cellar House
Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Cozy Oceano Beach Retreat
Enjoy this recently renovated space located just a couple minutes drive to the beach. Home features a well-equipped kitchen, washer and dryer, high speed Wi-Fi and Smart TV, fully-enclosed side yard with BBQ and outdoor dining, ample parking for cars and a trailer, beach towels, beach toys and board games. There is a great coffee shop, grocery store, multiple restaurants and a new park that is close to completion, all walking distance away. No cats please.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Spacious Whole Residence w/ Bikes--Close to Beach!
Single story 3bd/2ba home in a quiet informal neighborhood ~ 1.5 miles (30 min walk/10 min bike ride) to the beach. Full Kitchen, Washer/Dryer, Indoor Grill, Outdoor Grill, Waffle Iron, Pressure Cooker/Slow Cooker, Dutch Oven, Mixer, Blender, Bicycles w/Locks & Helmets, Wifi, Smart Tv's (in every bedroom and in the living room) and a Stand/Sit Desk with Computer, Printer/Fax/Scanner, plus other amenities...

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Beach home near golf, wineries, dunes & Vandenburg
This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

Beach-themed country home w/ backyard tiki hut
As 23-time Superhosts we welcome you! This adorable home is perfect for couples or families. Enjoy the relaxation of country living; yet just 15 mins from the beaches. We have included everything we could think of for you to have a stress-free and fun vacation; the softest of beds & linens, a fully-stocked kitchen, games, fire-pit , satellite tv/smart tv and beach gear.

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views
Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge
Popular amenities for house rentals in Guadalupe
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

San Luis Obispo House With Pool And Hot Tub

Mountain Sanctuary, Saltwater Pool

Getaway at the Highlands+Heated Pool+Hot Tub

Hot tub, heated pool (82 degrees), gas fire pit

Ranch Style Home w/ Bikes! Heart of Wine Country
Weekly house rentals

Baywood Park Garden Cottage

Chelsea’s on Victoria

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Great little beach house. County License# 6012116

Cozy Studio Close to Downtown SLO

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views

Coastal cottage in Pismo beach

Farmhouse located on San Luis Obispo Central Coast
Private house rentals

San Luis Obispo Wine Country Retreat

Los Olivos Vineyard Home on Winery Estate

Pelican Cove Vacation Rental at the Back Bay

Luxury Surfhouse 5Min to Pismo Walk to Restaurants

Blue Wave of Avila

Iconic Modern Farmhouse+walkable+views+BBQ

2735 Nokomis

Beach Home-walk to the Beach STR0116
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Northern California Holiday rentals
- Channel Islands of California Holiday rentals
- San Francisco Bay Area Holiday rentals
- San Diego Holiday rentals
- San Francisco Holiday rentals
- Gold Country Holiday rentals
- Central California Holiday rentals
- San Francisco Peninsula Holiday rentals
- Palm Springs Holiday rentals
- Cayucos Beach
- El Capitán State Beach
- Montaña de Oro State Park
- Natalie's Cove
- Arroyo Quemada Beach
- Gaviota Beach
- B & E Vineyard & Winery
- Morro Strand State Beach
- Refugio Beach
- Cayucos State Beach
- Seal Beach
- Mission San Luis Obispo de Tolosa
- Dairy Creek Golf Course
- Morro Rock Beach
- Pirates Cove Beach
- Morro Bay Golf Course
- Sand Dollars
- Olde Port Beach
- Spooner's Cove
- Point Sal State Beach
- Bovino Vineyards
- Bianchi Winery
- Baywood Park Beach
- Allegretto Wines




