
Holiday rentals in Orangeburg County
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Top-rated holiday rentals in Orangeburg County
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The salley house
Freshly renovated store front located in the heart of a friendly southern town. Not to expect luxury, but a spacious, comfy, and clean haven to meet your needs if you are passing through or visiting the area for a few days and need a place to stay while visiting family or eudora farms. It features 2 bedrooms, with two queen beds and a twin trundle. It is a roomy home and has a full kitchen and dining. Master bedroom is on the ground floor, and both bathrooms. Minor step ups on ground floors.

Lake Marion Cottage
Relax with the whole family at this lakefront 2 bedroom cottage on Lake Marion . Enjoy the screen porch overlooking deep water or fish from your private dock as you watch orange and red sunsets. Enjoy Grilling outdoors or cooking inside the open, fully stocked kitchen all while friends and family hang out in the double living room. Each room has its own smart tv so whether you retire early from your kayak/paddleboard adventure or stay up for s’mores and a movie, you will find a place to relax.

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

The Grand Marshall
Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Colonial Farmhouse - 6 bedroom with a pool
This private estate 4,355 s.f. (2,800 1st floor, 1,555 2nd floor) home was originally built around the year 1900 and features 6 bedrooms (3 upstairs, 3 downstairs) and 2.5 bathrooms (1.5 downstairs, 1 upstairs). It has 12 ft ceilings throughout, a large dining room, living room, and kitchen area, a beautiful foyer and large staircase, an office, laundry room, large porches, a fireplace, a carport, and a basketball court. You can conveniently walk on a paved walkway to the fenced pool area.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Santee lakefront home, big water right off I-95
Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Ellzey Place
Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

The Merry Inn @ Lake Marion
Take a break at the lake & relax at The Merry Inn @ Lake Marion for your next vacation! Built in 1959 and lovingly restored in 2024. Come see it soon! ***All reservations require a SIGNED RENTAL AGREEMENT and government issued PHOTO ID to complete booking (E-Sign document sent at booking). Thanks for taking a look, we look forward to having you as our guest! ***

Oak View
Enjoy having a cup of coffee relaxing in the swing on the front deck or sitting on the back deck facing the woods and watching the chickens pecking for food. Or take a stroll down the lane and inspect the muscadine/scuppernong vines and enjoy luscious grapes and figs in season. Enjoy a slice of country life on 2 1/2 acres.

Beautiful lakefront condo overlooking Lake Marion.
Beautiful condo located lakefront on Lake Marion in Santee, SC. This second floor unit has elevator or stair access. Balcony views the lake and pool just outside. This lake is popular for watersports and incredible fishing.
Popular amenities for Orangeburg County holiday rentals
Other great holiday rentals in Orangeburg County

The Sunset Chaser

Sunset Serenity Pool/Swim Spa

Beautiful Lake Marion Townhome

Lakefront w/ dock at Mill Creek

Trails End

Lowcountry river life

Nene's Cozy Corner

Lakeview Leisure-Face to the Sun
Destinations to explore
- Apartment rentals Orangeburg County
- Family-friendly rentals Orangeburg County
- Rentals with a kayak Orangeburg County
- Rentals with a washing machine and dryer Orangeburg County
- Rentals with pools Orangeburg County
- Rentals with a hot tub Orangeburg County
- Pet-friendly rentals Orangeburg County
- Hotel rooms Orangeburg County
- Fitness-friendly rentals Orangeburg County
- Rentals with outdoor seating Orangeburg County
- House rentals Orangeburg County
- Rentals with lake access Orangeburg County
- Rentals with a firepit Orangeburg County
- Rentals with a patio Orangeburg County
- Flat rentals Orangeburg County
- Rentals with a fireplace Orangeburg County
- Riverbanks Zoo and Garden
- South Carolina State House
- Congaree National Park
- Columbia Museum of Art
- University of South Carolina
- Frankie's Fun Park
- South Carolina State Museum
- Dreher Island State Park
- Saluda Shoals Park
- West Columbia Riverwalk Park and Amphitheater
- Sesquicentennial State Park
- Williams Brice Stadium
- Edventure
- Colonial Life Arena
- Columbia Metropolitan Convention Center
- Riverfront Park
- Soda City Market




