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Holiday rentals in Orangeburg County

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Top-rated holiday rentals in Orangeburg County

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Flat in Salley
4.99 out of 5 average rating, 109 reviews

The salley house

Freshly renovated store front located in the heart of a friendly southern town. Not to expect luxury, but a spacious, comfy, and clean haven to meet your needs if you are passing through or visiting the area for a few days and need a place to stay while visiting family or eudora farms. It features 2 bedrooms, with two queen beds and a twin trundle. It is a roomy home and has a full kitchen and dining. Master bedroom is on the ground floor, and both bathrooms. Minor step ups on ground floors.

Superhost
Two adirondack chairs, one blue and one green, are positioned on a wooden dock facing a tranquil lake. The setting sun casts warm orange and red hues across the sky, reflecting softly on the water's surface, highlighting the peaceful lakeside atmosphere.
Home in Summerton
4.8 out of 5 average rating, 10 reviews

Lake Marion Cottage

Relax with the whole family at this lakefront 2 bedroom cottage on Lake Marion . Enjoy the screen porch overlooking deep water or fish from your private dock as you watch orange and red sunsets. Enjoy Grilling outdoors or cooking inside the open, fully stocked kitchen all while friends and family hang out in the double living room. Each room has its own smart tv so whether you retire early from your kayak/paddleboard adventure or stay up for s’mores and a movie, you will find a place to relax.

Top guest favourite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 200 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Top guest favourite
A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.
Home in Orangeburg
5 out of 5 average rating, 142 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Guest favourite
The home features a classic two-story design with an inviting porch supported by tall columns. Green shrubs surround the property, and windows showcase black shutters. A red roof and a brick foundation accentuate the traditional architecture of the estate located on expansive grounds.
Home in Orangeburg
4.95 out of 5 average rating, 102 reviews

Colonial Farmhouse - 6 bedroom with a pool

This private estate 4,355 s.f. (2,800 1st floor, 1,555 2nd floor) home was originally built around the year 1900 and features 6 bedrooms (3 upstairs, 3 downstairs) and 2.5 bathrooms (1.5 downstairs, 1 upstairs). It has 12 ft ceilings throughout, a large dining room, living room, and kitchen area, a beautiful foyer and large staircase, an office, laundry room, large porches, a fireplace, a carport, and a basketball court. You can conveniently walk on a paved walkway to the fenced pool area.

Guest favourite
Home in Summerton
4.94 out of 5 average rating, 170 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favourite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 170 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Top guest favourite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 172 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favourite
A spacious bed is dressed with a light patterned duvet and decorative pillows. A black nightstand is positioned beside the bed, topped with a textured lamp and a small potted plant. The backdrop features green wainscoting, adding a calming touch to the room.
Flat in Barnwell
4.99 out of 5 average rating, 141 reviews

Ellzey Place

Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Top guest favourite
An aerial view of the property showcases a private pool next to a spacious lawn leading to the lake. The calm waters reflect the clear sky, while nearby docks provide access to boating activities. Lush trees frame the scene, enhancing the natural setting.
Home in Santee
5 out of 5 average rating, 16 reviews

The Merry Inn @ Lake Marion

Take a break at the lake & relax at The Merry Inn @ Lake Marion for your next vacation! Built in 1959 and lovingly restored in 2024. Come see it soon! ***All reservations require a SIGNED RENTAL AGREEMENT and government issued PHOTO ID to complete booking (E-Sign document sent at booking). Thanks for taking a look, we look forward to having you as our guest! ***

Top guest favourite
A living area features a plush sofa and a comfortable armchair beside a side table with a lamp. Natural light enters through a window adorned with sheer curtains. A decorative wall hanging and a wall art piece add subtle accents to the space.
Home in Barnwell
4.99 out of 5 average rating, 119 reviews

Oak View

Enjoy having a cup of coffee relaxing in the swing on the front deck or sitting on the back deck facing the woods and watching the chickens pecking for food. Or take a stroll down the lane and inspect the muscadine/scuppernong vines and enjoy luscious grapes and figs in season. Enjoy a slice of country life on 2 1/2 acres.

Top guest favourite
A spacious living area is furnished with a comfortable sofa and armchair, complemented by a wooden coffee table and decorative lamp. The room features an area rug with intricate patterns, enhancing the setting. A dining area is visible in the background, connected to the open kitchen.
Apartment in Santee
4.96 out of 5 average rating, 168 reviews

Beautiful lakefront condo overlooking Lake Marion.

Beautiful condo located lakefront on Lake Marion in Santee, SC. This second floor unit has elevator or stair access. Balcony views the lake and pool just outside. This lake is popular for watersports and incredible fishing.

Popular amenities for Orangeburg County holiday rentals