
Holiday rentals in Orangeburg County
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Top-rated holiday rentals in Orangeburg County
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The salley house
Freshly renovated store front located in the heart of a friendly southern town. Not to expect luxury, but a spacious, comfy, and clean haven to meet your needs if you are passing through or visiting the area for a few days and need a place to stay while visiting family or eudora farms. It features 2 bedrooms, with two queen beds and a twin trundle. It is a roomy home and has a full kitchen and dining. Master bedroom is on the ground floor, and both bathrooms. Minor step ups on ground floors.

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

The Grand Marshall
Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Colonial Farmhouse - 6 bedroom with a pool
This private estate 4,355 s.f. (2,800 1st floor, 1,555 2nd floor) home was originally built around the year 1900 and features 6 bedrooms (3 upstairs, 3 downstairs) and 2.5 bathrooms (1.5 downstairs, 1 upstairs). It has 12 ft ceilings throughout, a large dining room, living room, and kitchen area, a beautiful foyer and large staircase, an office, laundry room, large porches, a fireplace, a carport, and a basketball court. You can conveniently walk on a paved walkway to the fenced pool area.

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Ellzey Place
Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Spanish Moss (Carolina Cottage)
Enjoy the sounds of nature when you stay in this unique place. Wildlife, Magnolia’s, trees, Spanish Moss draped 200 year old Oak trees, Pecan Orchard Views. Private gated drive to cottage. The Bungalow at Magnolia is located on the same property which does not allow pets 120 feet distance wooded unable to see cottages from each other. 420 friendly property.

Oak View
Enjoy having a cup of coffee relaxing in the swing on the front deck or sitting on the back deck facing the woods and watching the chickens pecking for food. Or take a stroll down the lane and inspect the muscadine/scuppernong vines and enjoy luscious grapes and figs in season. Enjoy a slice of country life on 2 1/2 acres.

Modern apartment overlooking a Historic Downtown
Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

The Sunset Chaser
Escape all the hustle and bustle on the peaceful shores of Lake Marion with breathtaking views and sunsets. This newly built home will provide serenity to your vacation whether it be relaxing by the pool, golfing in Santee, fishing off the dock, or taking a cruise on the water.

Beautiful lakefront condo overlooking Lake Marion.
Beautiful condo located lakefront on Lake Marion in Santee, SC. This second floor unit has elevator or stair access. Balcony views the lake and pool just outside. This lake is popular for watersports and incredible fishing.
Popular amenities for Orangeburg County holiday rentals
Other great holiday rentals in Orangeburg County

Lake House at Lake Marion

Trendy, cozy and casual

The Pond House at Salkehatchie Farms

Lowcountry river life

Lakeview Leisure-Face to the Sun

Renovated Camper Farm Stay

The Merry Inn @ Lake Marion

Heated Indoor Pool on Lake Marion with Dock
Destinations to explore
- Flat rentals Orangeburg County
- Hotel rooms Orangeburg County
- Rentals with a hot tub Orangeburg County
- Rentals with a washing machine and dryer Orangeburg County
- House rentals Orangeburg County
- Fitness-friendly rentals Orangeburg County
- Family-friendly rentals Orangeburg County
- Rentals with a kayak Orangeburg County
- Rentals with a patio Orangeburg County
- Apartment rentals Orangeburg County
- Pet-friendly rentals Orangeburg County
- Rentals with outdoor seating Orangeburg County
- Rentals with a fireplace Orangeburg County
- Rentals with lake access Orangeburg County
- Rentals with a firepit Orangeburg County
- Rentals with pools Orangeburg County
- Riverbanks Zoo and Garden
- Congaree National Park
- South Carolina State House
- Columbia Museum of Art
- University of South Carolina
- Frankie's Fun Park
- South Carolina State Museum
- Dreher Island State Park
- Saluda Shoals Park
- West Columbia Riverwalk Park and Amphitheater
- Colonial Life Arena
- Columbia Metropolitan Convention Center
- Williams Brice Stadium
- Sesquicentennial State Park
- Edventure
- Soda City Market
- Riverfront Park




