
Guest house holiday rentals in Santa Ana
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Top-rated guest house rentals in Santa Ana
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Cozy 2-bedroom private guesthouse near South Coast
Step into this getaway house, away from all the hustle and bustle of daily life. You will find calmness and peace on your vacation. Indulge in a hot cup of coffee under the patio in a quiet environment or make your family a hot breakfast in the new kitchen before you head out to nearby attractions. Just bring your sun glasses and luggages. 5 minutes from South Coast Plaza. 25 Minutes from Disneyland Park. 20 minutes from all beautiful beaches, shopping centers and top restaurants of the region.

Quiet Peaceful Studio
Private studio apartment. Second-story unit, set back from the street, in a separate building behind the hosts' home. Located in a beautiful historic neighborhood, on a quiet street shaded by oak trees. Disneyland and the Anaheim Convention Center are only 10 minutes away. The Honda Center and Anaheim Stadium 5 minutes. The beaches are an easy 20 minute drive. Excellent restaurants and shopping are abundant. Close to Old Town Orange, Chapman University, and the Santa Artists Village.

Private Modern 1BR Suite, near Disney & Knott’s!
Private Suite with Spa Shower, Near Disneyland Relax in your own remodeled private suite with a separate entrance.The master bedroom features a comfy queen bed,lounge chairs,and essentials (note: no kitchen) Indulge in the spa-style bathroom with a large rain shower,6 body sprays, and a smart toilet have joy in the shower! 📍Just 4.8 miles from Disneyland 🎢 2 miles from Knott’s Berry Farm 🚗Minutes to the 5 & 91 freeways Perfect for a peaceful escape with easy access to top attractions!

Near Disney, Private, Fast Wifi, Self Check-in
Private Guesthouse in the Heart of Orange County! Enjoy your own peaceful retreat in this newly built, detached guesthouse nestled in a quiet residential neighborhood. This bright and modern space offers complete privacy with its own entrance and a fully fenced patio—perfect for morning coffee or evening relaxation. Centrally located in Orange County, you’ll be just a short drive from top attractions, beaches, shopping, and dining, while still enjoying a calm, cozy place to unwind.

Relax and revive at THE OASIS Poolside Bungalow
Relax, reset and revive in this chic and contemporary poolside bungalow with your own private pool and spa. The attention to detail in this mini-retreat will make you feel right at home. Lay out in sun or take a dip in the pool during the day and sit in the revitalizing spa at night. The bungalow is located within miles of many major attractions in OC such as Newport, Huntington and Laguna beaches, Disneyland, hiking trails and OC Fairgrounds. 2 guests maximum and NO PARTIES PLEASE

Aviary with Amazing Views!
Perched on a hilltop with Amazing Views, Our place is walking distance from CSU of Fullerton and Fullerton Arboretum. We are located off the 57 fwy and a 20 min drive to Disneyland! It is a tiny cottage with modern amenities and although the cottage is detached from the main home, there is a cottage directly below, where you may hear noise if occupied. You may never see us, but available if needed. Enjoy a tranquil space with sounds of morning birds, outdoor fountains and a dog!

Cozy King-Bed+SofaBed 6Mi Disney 1.6 Mi Hospitals
Luxury Unit with King-Size Bed, Relax and unwind in our fully equipped unit. With everything you need for a comfortable and enjoyable stay, you're sure to have a memorable time. The unit features: Spacious bedroom with a king-size bed, 54" TV, and a Desk. The Living-room has a sofa bed, making it the perfect place to relax. The kitchen is fully equipped with everything you need. Whether you're on a business trip, vacation, or simply need a place to stay for a few nights.

D'Loft By JC
D'Loft is newly built in July 2023. Your family will be close to everything when you stay at this centrally-located place. We are located 10-15 Min from Disneyland, the beach, shopping and much more! D'Loft features an open concept design, dressed in high end appliances and it's own private patio. Relax in a comfy Cal King Bed in addition to a queen size sofa bed + a twin sleeper, available at your disposal. Open the double sliders and make indoor outdoor space!

Private Cottage near Disney, Chapman U and Orange Plaza
Enjoy the waves, explore Disney, or visit Old Towne Orange and Chapman University, then unwind in this cozy garden retreat. Meeting or exceeding CDC and Airbnb cleaning standards, this clean and cozy guest house will delight with kitchen, bathroom, queen bed, wifi and attached patio space. Tucked behind the main house in a garden setting, you’ll feel safe and secure. Driveway/side gate entrance to garden and guesthouse. Perfect for 1-2 guests.

Safe+Comfy! * 11 Min to Disneyland * Fruit Trees
Clean. Quiet. Comfortable. Safe! 11 minutes to Disneyland, this 1BR/1BA newly-renovated guesthouse in Santa Ana offers a relaxing atmosphere. Explore a beautiful yard w/Flowers+Organic Fruit Trees! Private & separate (doesn’t share walls w/main home). Safe and walkable neighborhood adorned w/gorgeous Gardens+Architecture. Centrally located within a 5-mile radius of theme parks, event venues, restaurants and shops. Relax, you've arrived.

The Casita Blanca, Private Guesthouse near Disney
Welcome to the Casita Blanca, located in the heart of sunny Orange County. The detached guesthouse, a private and quiet space, has a Spanish charm and is walking distance from the restaurants and shops in Downtown Santa Ana Arts District. It is located just 5 miles from Disney, 12 miles from beaches, 6 miles from John Wayne Airport and 40 miles from LAX. The casita is comfortable for 4 people with one queen bed + a full size pull out.

Midcentury studio w chef's kitchen
Located on a beautiful, tree-lined street in an historic neighborhood which is centrally located. Disneyland, Honda Ctr, Angels Stadium, St. Joseph’s Hospital, Chapman University, Anaheim Convention Ctr, John Wayne Airport and Newport Beach are just a few miles by car. LAX is 33 miles away. High powered AC and Heater. Hi-speed WiFi and Smart TVs. Very quiet, clean and comfortable.
Popular amenities for guest house rentals in Santa Ana
Family-friendly guest house rentals

Orange Slice - Near Disneyland, Chapman Univ.

Cozy city hideaway for families.

Urban Retreat

Cozy Long Beach guest house with hot tub

Adorable Hillside Cabin

Welcom 3bedroom,2bath guesthouse Westminster OC

Charming Studio Guesthouse, Ideal for OC Getaways

Gorgeous family friendly 2 bdrm - 12 min to Disney
Guest house rentals with a patio

Luxury Cottage Near Old Town, Rosebowl, and More

An LA Escapade.

Adorable Back House w/Secluded Garden & Yard

Private Spanish Guesthouse w/ Pool & Views

Huntington Beach Hideaway

Adorable 1 bedroom house with pool and patio

Adorable little guest house with beautiful garden

Modern Hillside Escape surrounded by Nature
Guest house rentals with a washing machine and dryer

Cozy Guesthouse Surrounded by Nature

Charming 2 br condo nr. beach

1919 Spanish Casita | 12 min. to Anaheim

Cozy guest home in O.C with 2 rooms

Southbay Hideaway: Garden Oasis featuring hot tub!

Modern Cottage Central to Disney, Universal & DTLA

Private guest retreat, 15 to Disney and beach

Stroll to Plaza or Chapman U from the ORANGE GEM
Quick stats about guest house rentals in Santa Ana
Total rentals
80 properties
Nightly prices starting at
£37 before taxes and fees
Total number of reviews
7.6K reviews
Family-friendly rentals
20 properties are a good fit for families
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Wifi availability
80 properties include access to wifi
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- Venice Beach
- Santa Catalina Island
- Disneyland Park
- Santa Monica Beach
- Universal Studios Hollywood
- Los Angeles Convention Center
- Oceanside City Beach
- Crypto.com Arena
- SoFi Stadium
- Hollywood Walk of Fame
- Santa Monica State Beach
- University of California, Los Angeles
- University of Southern California
- Rose Bowl Stadium
- San Clemente State Beach
- Knott’S Berry Farm
- Huntington Beach, California
- The Forum
- San Onofre Beach
- Bolsa Chica State Beach
- Disney California Adventure Park
- Pechanga Resort Casino
- Oceanside Harbor
- Topanga Beach