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House holiday rentals in Santa Cruz County

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Cruz County

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A well-maintained yard features mature trees providing shading, with a spacious lawn that stretches towards the hacienda. The structure's exterior is characterized by a traditional design, complemented by a covered porch area. Clouds drift in the sky, hinting at a serene atmosphere.
Home in Arivaca
4.86 out of 5 average rating, 119 reviews

Private Getaway: Pandora Ranch House in Arivaca

Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

Top guest favourite
The spacious ranch house is situated on a gravel driveway, surrounded by green grass and gently rolling hills. A clear blue sky with wispy clouds serves as a backdrop, highlighting the peaceful rural setting and bringing attention to the home's exterior features.
Home in Sonoita
4.94 out of 5 average rating, 103 reviews

McFitz Guest Ranch

McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

Top guest favourite
Home in Patagonia
5 out of 5 average rating, 12 reviews

Camp Cathy

Kick back at this fully furnished hilltop getaway in a quiet gated community above Patagonia. Built for comfort and entertaining, enjoy sweeping mountain views, epic sunsets, and starry nights. The split floor plan offers privacy with 3 bedrooms and 2 baths, TVs in every room, and a dedicated game room for all ages. Fire up the BBQ, lounge in spacious outdoor seating, and stroll into town. Peaceful, private, and perfect for romantic getaways or small group entertaining. Relax, play, repeat!

Guest favourite
A stylish living area features a large flat-screen TV positioned above a modern fireplace. A comfortable tan sofa and armchairs are arranged on a vibrant patterned rug. Natural light filters through the window shades, illuminating a decorative console table and colorful wall art.
Home in Tubac
4.94 out of 5 average rating, 18 reviews

Cozy 2 bedroom townhouse, Tubac

Kick back and relax in this calm and stylish space. Located in a wonderful Barrio community of Tubac. 2 bedrooms and 2 bathrooms with a nice patio overlooking the mountains. There is a nice outdoor heated pool and workout center. Close to the long and scenic Anza trail perfect for hiking and birdwatching. Walking distance to the town center and all the artsy little shops in town. Both bedrooms have comfortable queen size beds and office tables. Townhouse has a water filtration system.

Guest favourite
A southwestern-style ranch home is nestled on expansive land, surrounded by rolling plains. The structure features a white exterior with traditional architectural elements. Majestic mountains are visible in the distance under a clear sky, enhancing the serene rural landscape.
Home in Elgin
4.93 out of 5 average rating, 167 reviews

Peaceful SW-style ranch home in wine country

Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

Top guest favourite
A dining area features a long wooden table surrounded by six dark chairs. A large chandelier shaped like a star hangs above the table, casting intricate patterns on the walls. A decorative centerpiece of fresh fruits adds a touch of color.
Home in Tubac
5 out of 5 average rating, 142 reviews

A Tubac Getaway

Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Guest favourite
A spacious living area features a light-colored sofa with colorful accent pillows and a glass coffee table. Artwork adorns the walls, while natural light filters in through a window. A dining area with chairs and a modern workspace is visible in the background.
Home in Patagonia
4.94 out of 5 average rating, 110 reviews

Cottage on Santa Rita | Sundrenched 2 bd/1 bth

Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Top guest favourite
Home in Sonoita
5 out of 5 average rating, 31 reviews

The Somm's Aviary

Welcome to our peaceful home in Sonoita Meadows just off Hwy 83, perfectly situated between the exceptional Sonoita-Elgin wineries and prime birding grounds of Patagonia-Sonoita Creek. Explore by day, then unwind under the stars by a cozy firepit from your private patio. Your getaway awaits! Dual zone wine fridge? Check. Birding binoculars? Check. Outdoor grill? Of course. Plus a 75" TV and board games for the homebody in you.

Top guest favourite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 287 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Top guest favourite
A covered patio area features two comfortable seating arrangements and a swing with plush cushions. A coffee table rests in the center, surrounded by views of the expansive grassland and hills in the distance. Natural light floods the space, enhancing the rustic wooden beams overhead.
Home in Sonoita
5 out of 5 average rating, 66 reviews

2 min to wineries | Chef Kitchen | Kings | PetsOK

-HILLTOP VIEWS! -2 minute drive to vineyards -Blackout curtains + 3 king beds -6 minutes to Santa Cruz County Fairgrounds -1,392 square feet -Crockpot, blender, hand mixer, spices -380+Mbps wifi (uncommon for this rural area) -Covered front porch with twin-sized swing -2.75-acres - hilly, fenced grassland -Bluetooth speaker -Onsite, covered parking for 2 vehicles -Blackstone griddle -44 minutes to Parker Canyon Lake

Top guest favourite
A clear blue pool is visible, reflecting sunlight under a vast sky adorned with fluffy white clouds. The surrounding landscape features rolling hills and mountains in the distance, highlighting the serene nature of the location.
Home in Patagonia
4.94 out of 5 average rating, 65 reviews

Poolside Escape Near Patagonia

Unwind at this scenic hilltop retreat just a mile south of Patagonia, AZ. Enjoy a private pool with stunning Red Mountain views, 3 spacious bedrooms, and a dedicated office space. Close to hiking, biking, and town. Relax in modern comfort, soak up breathtaking sunsets, and explore the best of Southern Arizona. Pet-friendly for making memories with the whole family!

Top guest favourite
A modern kitchen area features wooden cabinetry and stainless steel appliances, including a stove and refrigerator. Natural light fills the space through the window, and a cozy dining table is set nearby. Decorative elements, such as wall art, enhance the inviting design.
Home in Sonoita
4.99 out of 5 average rating, 352 reviews

Winemaker's Casita in the heart of Wine Country

The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.

Popular amenities for house rentals in Santa Cruz County