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House holiday rentals in Santa Cruz County

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Cruz County

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A well-maintained yard features mature trees providing shading, with a spacious lawn that stretches towards the hacienda. The structure's exterior is characterized by a traditional design, complemented by a covered porch area. Clouds drift in the sky, hinting at a serene atmosphere.
Home in Arivaca
4.86 out of 5 average rating, 119 reviews

Private Getaway: Pandora Ranch House in Arivaca

Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

Top guest favourite
The spacious ranch house is situated on a gravel driveway, surrounded by green grass and gently rolling hills. A clear blue sky with wispy clouds serves as a backdrop, highlighting the peaceful rural setting and bringing attention to the home's exterior features.
Home in Sonoita
4.94 out of 5 average rating, 102 reviews

McFitz Guest Ranch

McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

Top guest favourite
A serene landscape features rolling mountains bathed in warm light from a setting sun. The view encompasses lush greenery and a dirt path leading to a guest house nestled among the hills, highlighting a peaceful rural retreat.
Home in Patagonia
5 out of 5 average rating, 36 reviews

Serenity, Starlink and waking up with bird songs

Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

Superhost
A single-story home is presented, featuring a neutral-colored exterior with a pitched roof. A spacious driveway leads to a double garage, while a wrought iron gate enhances the entrance. Desert landscaping with native plants surrounds the property, complemented by a clear blue sky above.
Home in Rio Rico
4.88 out of 5 average rating, 8 reviews

Desert Oasis Retreat

Relax with the whole family at this beautiful home. Our home has 3 bedrooms. Master suite with large walk-in closet, TV in room. Double sink vanity and a large soaking tub/shower. Second bedroom has a double size bed and walk-in closet, TV in room. Third bedroom has trundle bed (basically two twin beds and large closet. Beautiful living room, comfy family room and all appliances kitchen. Dining area seats 6. Located in the quiet hills of Rio Rico. Valley scenery to enjoy in the evening.

Guest favourite
A southwestern-style ranch home is nestled on expansive land, surrounded by rolling plains. The structure features a white exterior with traditional architectural elements. Majestic mountains are visible in the distance under a clear sky, enhancing the serene rural landscape.
Home in Elgin
4.93 out of 5 average rating, 165 reviews

Peaceful SW-style ranch home in wine country

Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

Top guest favourite
A dining area features a long wooden table surrounded by six dark chairs. A large chandelier shaped like a star hangs above the table, casting intricate patterns on the walls. A decorative centerpiece of fresh fruits adds a touch of color.
Home in Tubac
5 out of 5 average rating, 142 reviews

A Tubac Getaway

Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Guest favourite
A spacious living area features a light-colored sofa with colorful accent pillows and a glass coffee table. Artwork adorns the walls, while natural light filters in through a window. A dining area with chairs and a modern workspace is visible in the background.
Home in Patagonia
4.94 out of 5 average rating, 109 reviews

Cottage on Santa Rita | Sundrenched 2 bd/1 bth

Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Top guest favourite
An open living area features a high, vaulted ceiling with exposed wooden beams. Large windows offer natural light and views of the surrounding trees. A brown sectional sofa surrounds a coffee table, while a blue storage cabinet and a television complete the space. Dining chairs and a table are visible to one side.
Home in Patagonia
5 out of 5 average rating, 84 reviews

Patagonia's Private Paradise

$100 PER NIGHT SUMMER IN PATAGONIA IS A WONDERFUL TIME SUMMER DISCOUNT READ OUR REVIEWS BEFORE YOU CHOOSE Patagonia is located high in the SKY ISLANDS of Southeast Arizona. The higher elevation and mountain forests make Patagonia much cooler than the Arizona cities at a lower elevation. Come to Patagonia and enjoy great discounts for longer-term stays at a time of year that many find nice and green. 20% OFF FOR 7 NIGHTS OR MORE 35% OFF FOR 28 DAYS OR MORE

Top guest favourite
Home in Patagonia
5 out of 5 average rating, 7 reviews

Peaceful Family Friendly + Fire Pit + Volleyball

Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Top guest favourite
The entrance of the house is framed by a metal gate and features a pathway leading to the front door. The structure showcases a modern design with a metal roof, flanked by two windows. Native plants and grasses are visible in the surrounding landscape.
Home in Elgin
4.95 out of 5 average rating, 62 reviews

Sonoita Harvest Home - minutes from wineries

Relax and unwind in the heart of Arizona wine country. 4 sprawling acres, stunning views, just minutes from top-local wineries and restaurants. The house boasts 2100 square feet with 3 bedrooms, office, 2.5 bathrooms and sleeps 9-10. Large modern kitchen and open living spaces. Perfect for friends, families and couple getaways. Sip wine on the back patio, explore local wineries, and enjoy your own slice of countryside paradise!

Top guest favourite
Home in Sonoita
5 out of 5 average rating, 26 reviews

The Somm's Aviary

Welcome to our peaceful home in Sonoita Meadows just off Hwy 83, perfectly situated between the exceptional Sonoita-Elgin wineries and prime birding grounds of Patagonia-Sonoita Creek. Explore by day, then unwind under the stars by a cozy firepit from your private patio. Your getaway awaits! Dual zone wine fridge? Check. Birding binoculars? Check. Outdoor grill? Of course. Plus a 75" TV and board games for the homebody in you.

Top guest favourite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 285 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Popular amenities for house rentals in Santa Cruz County