Some info is shown in its original language. Translate

Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1
Guest favourite
Home in Puerto Ayora
5 out of 5 average rating, 51 reviews

Villa Náutica | Jacuzzi Privado | Diseño

Perfecta para parejas, familias o amigos que buscan relajarse con estilo en Galápagos Villa Náutica es una elegante villa loft con jacuzzi privado, amplios espacios y un diseño náutico único inspirado en mis raíces suizas y galapagueñas Ubicada en un tranquilo barrio residencial, te permite disfrutar de la tranquilidad a solo 12 minutos caminando del centro de Puerto Ayora. Combina comodidad, autenticidad y el ambiente ideal para descubrir las islas y regresar a descansar en un acogedor refugio

Top guest favourite
The sitting area features a modern gray sofa adorned with decorative pillows and is complemented by a wooden coffee table. Artwork hangs on the walls, and large glass doors provide ample natural light and views of a private balcony and the surrounding greenery.
Flat in Puerto Ayora
4.92 out of 5 average rating, 212 reviews

Planet House Apt2 Sunny 1 BR flat. Great location

This is a beautiful legally registered property, with great views and wonderful fresh ocean breeze. Our apartment is located two blocks away from Charles Darwin Avenue. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, great restaurants, cafés, shops, dive shops, tour operators and more. Great option for guests seeking flexibility, comfort and good value. The bedroom has AC, however the living area only benefits from a nice sea breeze.

Top guest favourite
Tiny home in Puerto Ayora
4.96 out of 5 average rating, 67 reviews

Tree house in the Mangrove

Enjoy the tranquility in Franklin's bay twenty minutes from the busy town of Puerto Ayora. You can see sealions, marine iguanas , sally light foot crabs, lava herons , great blue herons, pelicans, turtles, blue footed boobies while you are relaxing on the terrace of the Tree house. A life enhancing place to relax, write, read , paint, recharge, swim, do yoga on the large terrace, enjoy each moment. Listen to the soothing music of the sea while you doze. Franklin , built the tree house.

Top guest favourite
Cabin in Santa Cruz
4.96 out of 5 average rating, 210 reviews

Casa Vikingo • Secluded Galápagos Highland Cabin

Perched in the Galapagos Highlands on the drier east side of Santa Cruz, Casa Vikingo is a tropical modern cabin designed for those seeking nature, architecture, and complete privacy. Surrounded by endemic forest and built from materials found on site, the cabin is immersed in one of the most unique landscapes in the archipelago. Wake up to views of the Pacific and drifting cloud formations, soak in the private plunge tub, and experience a side of the Galápagos that few visitors ever see.

Guest favourite
Home in Puerto Ayora
5 out of 5 average rating, 8 reviews

Samana Stay

Samana Stay is a spacious two-level family home in a quiet walkable neighbourhood, with beaches and the Charles Darwin Research Station nearby. Designed for comfort and long stays, it offers generous living areas, air-conditioned downstairs bedrooms, reliable Wi-Fi, and a fully equipped kitchen. The open living and dining space opens to a private garden with cut lava-rock pathways, creating a calm outdoor retreat and complete “entire home” privacy, ideal for families and eco-travellers.

Top guest favourite
A bright common area features two comfortable sofas with decorative cushions and a wooden coffee table at the center. A TV is placed on an easel, and vibrant wall art adds character to the space. The open layout is enhanced by wooden beams and pendant lighting.
Flat in Puerto Ayora
4.96 out of 5 average rating, 193 reviews

Updated apartment close to centre of town

Our private, bright, spacious apartment is centrally located in Puerto Ayora close to Darwin Avenue. Restaurants, shops, Darwin Station and the main passenger pier are just a few minutes walk away. The apartment is equipped with wifi, large kitchen with fridge, induction stovetop and microwave, and a large common area. It is good for couples, families or small groups. There are two bedrooms with A/C and sofa beds so a family group can easily be accommodated. Patio available upstairs.

Guest favourite
Holiday home in Puerto Ayora
4.95 out of 5 average rating, 80 reviews

Brand new apartment in the heart of Puerto Ayora

Our home blends the soul of Galápagos with modern comfort, using solar panels for water systems and high-speed Starlink. Enjoy safe drinking water from a dedicated tap in the kitchen, savor local organic coffee in your fully equipped kitchen, snorkeling gear, and beach towels for your adventures. After your excursions, find peace on our terrace or the BBQ patio, then refresh with our washer, dryer, and detergent. Where sustainable living meets the gentle rhythm of island life.

Top guest favourite
The bright bedroom features two spacious beds with patterned bedding. Wooden beams add character to the ceiling while light fixtures create a warm ambiance. A large window allows natural light to fill the room, and a piece of art depicting a tree adorns one wall.
Bungalow in Puerto Ayora
4.9 out of 5 average rating, 310 reviews

Bright Garden Bungalow in a quiet neighborhood.

Sunshine filled, bright garden suite, next to the entrance to the Galapagos National Park and the Charles Darwin Station, and a few blocks away from some of the best restaurants, art galleries and bars in town. Located on the far end of one of Puerto Ayora's main streets, accessible to the road but removed enough to be isolated from the urban noise. An AC cools the suite when needed in the warmer months, and it’s screened windows are the alternative as well .

Top guest favourite
A charming exterior of a private accommodation is presented, featuring a rustic wooden door framed by lush greenery and colorful flowering plants. The natural stone pathway leads to the entrance, enhancing the inviting atmosphere of the serene outdoor space.
Home in Puerto Ayora
4.89 out of 5 average rating, 159 reviews

House El Galapagueño

Ven! Disfruta de la sencillez de este mágico alojamiento tranquilo, céntrico y Privado con tu Pareja, Familia o Amigos! Un lugar ideal para descansar después de las visitas a los sitios turísticos más extraordinarios de las Islas Galápagos!!! 🏡🐢🏞️🏝️☀️🐚 Te Esperamos!!! A 15 minutos a pie del Malecón A 100 metros de la entrada de la Playa Tortuga Bay A 20 metros de la Cancha de Tennis

Guest favourite
The exterior of a modern villa is displayed, featuring a curved stone entryway and lush greenery lining the pathway. The two-story structure is adorned with large windows and a sloped roof, providing a welcoming ambiance to visitors.
Home in Puerto Ayora
4.89 out of 5 average rating, 75 reviews

Hermosa Casa con la Mejor ubicación en Santa Cruz

Relájate con toda la familia en este alojamiento donde la tranquilidad se respira. ubicado en uno de los vecindarios más exclusivos y elegantes de puerto Ayora, a escasos 200 metros de distancia del acceso al sendero de la playa tortuga Bay, muy tranquilo y alejado de la bulla de la zona comercial. la casa se encuentra cerca del malecón y a pocos pasos de restaurantes y supermercados.

Top guest favourite
A well-lit living area features large windows offering panoramic views of the bay. A comfortable sofa and armchairs are arranged around a minimalist wooden coffee table. A wall-mounted television is positioned above a sleek sideboard, enhancing the space's modern feel.
Flat in Puerto Ayora
5 out of 5 average rating, 58 reviews

Modern Suite with the Best Sea View

Descubre la suite más lujosa con vistas panorámicas a la bahía que superan a cualquier otra propiedad en la zona Baysight es una nueva propuesta a través de una Suite en un edificio de 4 pisos, más terraza, ubicado en la avenida Charles Darwin, A solo un paso de restaurantes, tiendas, bancos, mercado, cafeterías, operadores turísticos y más sitios de tu interés.

Superhost
A modern living area features a light-colored sofa, natural fiber pendant lighting, and woven wall art. A television mounted on a wooden stand displays various media, while a small table is adorned with potted plants and decorative items. Natural light filters through sheer curtains covering a large window.
Flat in Santa Cruz
4.91 out of 5 average rating, 74 reviews

Galápagos BoHo

Galápagos BoHo: Un refugio para viajeros de espíritu libre Descubre el paraíso en las islas Galápagos, donde la naturaleza se encuentra con el confort en un ambiente bohemio y relajante. Galápagos BoHo es el destino ideal para aquellos que desean escapar de la rutina y sumergirse en un entorno donde cada rincón cuenta una historia.

Popular amenities for Santa Cruz holiday rentals

Destinations to explore

  1. Airbnb
  2. Ecuador
  3. Galápagos
  4. Santa Cruz