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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern studio layout is featured, with a spacious bed adorned with crisp white linens. A wooden kitchenette is visible in the background, while a dining area with a round table and orange chairs is also present. Natural light streams in from a nearby window.
Flat in Condesa
4.85 out of 5 average rating, 642 reviews

Modern Loft with Balcony & View of Parque Mexico

-Modern, brand new building -Rooftop terrace and brand new gym with views of Parque México and Reforma, -Fully-furnished unit designed for long stays and corporate travel -Free laundry facilities -Housekeeping service: Once a week for reservation of +7 nights Nido Parque Mexico is an incredible architectural accomplishment with the absolute best location in the entirety of Mexico City, on the corner overlooking Parque Mexico, in the heart of la Condesa. With a brutalist facade, ultra-modern in

Superhost
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Coyoacán
4.87 out of 5 average rating, 228 reviews

Loft de Casa Mavi en Coyoacán

¡Bienvenidos a Coyoacán! Estupendo loft de 120 m2 ubicado a tan solo 5 minutos caminando del Centro de Coyoacán. Vive la experiencia de este tranquilo e iluminado espacio abierto, ideal para descansar o trabajar y decorado con objetos llenos de historias. El loft se encuentra en el tercer piso de Casa Mavi, una antigua fábrica que fue remodelada para crear un lugar lleno de encanto que lo hace único. Cuenta con terrazas de uso común. Con opción para un tercer huésped. Wifi 200 megas.

Guest favourite
The image captures a spacious terrace adorned with various potted plants, leading to a bright bedroom area. Large glass doors open to the patio, allowing natural light to fill the space. A serene landscape and a clear blue sky complement the vibrant greenery.
Loft in Santa María La Ribera
4.96 out of 5 average rating, 348 reviews

Sunny loft with a big terrace in a historic area

New and spacious two stories loft on an award winning renovated building from the 1940´s. Security 24/7 , personal digital code to access the apartment, wifi, fully equipped kitchen, Smart TV with Netflix/Mubi, and a shared laundry room in the building. The loft has one patio in the first floor and a huge terrace full of plants on the second floor next to the bedroom. It is usually very quite but there could be a little noise during the day if another apartment is doing renovations.

Top guest favourite
A welcoming living area is highlighted by wooden flooring and large windows allowing natural light to fill the space. Two armchairs are positioned in front of a coffee table, where a book about mural painting is visible. A fireplace provides a cozy focal point in the background.
Home in Del Carmen
4.95 out of 5 average rating, 391 reviews

Casa José Clemente Orozco Coyoacán

Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.

Guest favourite
Loft in Tabacalera
4.85 out of 5 average rating, 108 reviews

Loft w/ Pool & Terrace | Reforma Downtown CDMX

Modern and functional loft in the heart of Mexico City, ideal for travelers who prioritize location, design, and urban connectivity. Features a terrace and pool, gym, and sauna. Prime location on Reforma, near the Palace of Fine Arts, Zócalo, Condesa, Roma, and a wide array of cultural, gastronomic, and nightlife options. Whether you're visiting for cultural tourism or an urban getaway, this space combines style, comfort, and convenience. Relax, explore, and create unforgettable moments

Guest favourite
Flat in Roma Norte
5.0 out of 5 average rating, 11 reviews

Designer's Haven in Roma with Private Rooftop

Experience Mexico City like a local from this beautifully designed three-story home in the heart of Roma Norte. Walk to the city's best restaurants, cafés, boutiques, galleries, and parks. Accommodates up to 6 guests with 3 bedrooms, 3 full bathrooms, a spectacular private rooftop terrace, 4 Smart TVs, private elevator access, parking, and 24/7 security. A rare combination of space, privacy, design, and location in one of the city's most desirable neighborhoods.

Guest favourite
Casa particular in Álvaro Obregón
4.94 out of 5 average rating, 32 reviews

Mi Refugio San Angel

Mi Refugio San Angel, is a spacious and modern space, to feel out of the city, being centrally in it. It has a Temazcal (under reservation), hydromassage tub, terraces, garden with hammocks, lounge chair, outdoor dining area, bonfire area, indoor fireplace. 2 rooms with full bathroom, queen size sofa bed; open, spacious and fully equipped kitchen. Private parking. The main room can be opened to a view towards the double height of its large room.

Guest favourite
Cabin in Tlalmanalco
5.0 out of 5 average rating, 12 reviews

Casita cerca a los volcanes.

Casita de pueblo cerca de los volcanes Disfruta una escapada única en nuestra acogedora casita, ideal para 2 a 4 personas. Perfecta para familias que desean pasar un fin de semana tranquilo y acogedor. Incluye: Cama (King Size) + sofá cama (King Size) Cocinita Frigobar Horno de microondas Tv Wifi Accesorios de cocina Vive la experiencia local con comodidad y encanto, muy cerca de los volcan.

Luxe
Flat in Polanco
4.98 out of 5 average rating, 160 reviews

Private and Quiet Balcony Residence in Polanco

Two-bedroom, two-bathroom with private balconies features a kitchen + dining perfectly laid out for a sociable setting or work from home. Tasteful furnishings, attention to detail, designer lighting and artful accessories make for an inspired experience. Stroll to Polanco's reknown retail shops and indulge in the city's best culinary experiences. 113 m2/370 sq ft

Top guest favourite
A charming outdoor patio is surrounded by vibrant greenery and a blue-walled house. A round glass table is complemented by six white metal chairs, creating an inviting space for dining or gathering. Potted plants and flowers add color to the serene environment.
Home in Coyoacán
4.97 out of 5 average rating, 109 reviews

Casa Omac | Colonial house with two patios

Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.

Top guest favourite
Guest house in Xochimilco
5.0 out of 5 average rating, 50 reviews

Jardín y hermosa casa para eventos y estancia

Jardín de eventos Camino Real Desconecta de tus preocupaciones en este espacio tan amplio y sereno. Ideal para todo tipo de eventos, fiestas infantiles, reuniones, bodas, eventos corporativos, talleres, cursos de yoga o cualquier otro ejercicio o actividad al aire libre 🍃🌿🌤️

Guest favourite
A welcoming entrance is displayed with a wooden door featuring decorative glass. Large windows with striped curtains allow natural light to brighten the space. Potted plants line the area, contributing to a serene ambiance. A small decorative item is hung next to the door.
Home in Tláhuac
5.0 out of 5 average rating, 47 reviews

Bonita casa en zona oriente

Alojamiento ideal para grupos pequeños, ambiente tranquilo y familiar. Pensado para estancias cómodas y con todos los servicios. Cerca del metro Nopalera, del Hospital General del ISSSTE, del Hospital General de Tláhuac, de la Universidad Marista y de plaza Las Antenas.

Popular amenities for Santa Cruz holiday rentals