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Holiday rentals in Santo Domingo de Guzman

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santo Domingo de Guzman

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
A modern living room is displayed, featuring a sleek wall-mounted TV with a decorative fireplace visual. Soft lighting highlights the textured wall behind. A spacious sofa and stylish chairs provide comfortable seating, while large windows allow natural light to enter the space.
Flat in Julieta Morales
4.82 out of 5 average rating, 512 reviews

✔️ CITY CENTER | LUXURY 2-BEDR. APT. | GREAT VIEWS

✅ BEST downtown LOCATION ✅ PRIVATE balcony with lounge area + Stunning City Views ✅ Shared ROOFTOP Gym, BBQ & Lounge Area ✅ 3 SMART TVs with Amazon Fire 1000+ MOVIES & International TV CHANNELS ✅ High-speed WIFI ✅ FREE private indoor parking ✅ Washer and dryer IN UNIT ✅ 24/7 Reception ✅ Fully Equipped LUXURY kitchen ✅ QUEEN size beds ✅ XL Dining table with space for 8 guests ✅ Great SOUND system ✅ AC in the living room & bedrooms ✅ PRIVATE and QUIET ✅ Steps away from BLUE MALL, LA SIRENA & BRAVO

Guest favourite
An outdoor area features a vibrant blue pool surrounded by lush greenery. Several white patio chairs and a table are positioned nearby, offering a relaxed seating option. A barbecue grill is visible in the background, complementing the inviting, tropical atmosphere.
Home in Santo Domingo
4.82 out of 5 average rating, 60 reviews

Experience Ultimate Comfort | 4BR Home

Welcome to our magnificent two-story, 4-bedroom house, nestled just moments away from the vibrant city center! Boasting an ideal combination of comfort, style, and convenience, this spacious retreat is the perfect home base for exploring the area's top attractions, trendy restaurants, and local hotspots. Indulge in the luxurious amenities and well-appointed spaces, ensuring a memorable stay for families, friends, and business travelers alike. Don't miss the chance to experience this.

Guest favourite
A modern living area is featured with a spacious sectional sofa, designed for comfort. A large TV is mounted on a sleek black wall, while floor-to-ceiling windows showcase a city skyline at sunset. Elegant lighting fixtures add a contemporary touch to the space.
Flat in Ensanche Quiqueya
4.93 out of 5 average rating, 74 reviews

NEW! Luxury Stay in the Heart of Santo Domingo

Welcome to our luxurious modern apartment! Featuring sleek design, marble finishes, and floor-to-ceiling windows with stunning city views, this space offers comfort and style. Relax in the spacious living area with a large TV, enjoy meals in the elegant dining space, and unwind in a cozy, upscale atmosphere. Thoughtful details, contemporary lighting, and plush furnishings make this the perfect retreat for travelers seeking sophistication and relaxation. Your ideal getaway awaits!

Guest favourite
Flat in Santo Domingo
4.96 out of 5 average rating, 92 reviews

Walk to Agora Mall—Exclusive Condo w/Rooftop Pool

Stay in one of Piantini’s most sought-after apartments — a modern luxury space with rooftop pool and stunning panoramic city views. Enjoy a full gym, play area, and private parking with 24/7 security. Walk to Blue Mall, Ágora, and Galería 360, surrounded by top restaurants, cafés, and cinemas. Ideal for business or leisure guests seeking comfort, convenience, and style. Includes fast Wi-Fi and Smart TV with Netflix, Disney+, and Prime Video.

Guest favourite
Flat in Viejo Arroyo Hondo
4.9 out of 5 average rating, 81 reviews

Comfortable Central Apartment

Modern and spacious accommodation in the heart of Santo Domingo. Enjoy a spectacular rooftop pool with a panoramic view of the city and feel at home thanks to its warm design. Located right in front of the Galería 360 shopping center, with shops, entertainment and a variety of restaurants within walking distance. Ideal for families, couples, or travelers looking for comfort, style, and a prime location. Everything is nearby!

Guest favourite
A modern living space is captured, featuring a light-colored sofa paired with two decorative wall art pieces. A tall indoor plant adds a touch of greenery, while natural light filters through sheer curtains. A dining table and chairs are arranged nearby, creating a welcoming atmosphere.
Apartment in Santo Domingo
4.91 out of 5 average rating, 163 reviews

Luxury Designer Apartment 2BR Prime Santo Domingo

Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.

Top guest favourite
A stylish living room is presented featuring a comfortable white sofa adorned with orange and brown throw blankets. A round black coffee table is centered on a geometric area rug, with two textured dark green chairs nearby. Large windows allow natural light to brighten the space.
Flat in Viejo Arroyo Hondo
4.94 out of 5 average rating, 220 reviews

Luxury Apartment Centrally

This luxurious apartment has the main amenities to have an unforgettable vacation. We have a minibar, a swimming pool with an infinite view, a spectacular balcony, located in the very center of the city, next to Galería 360, 3-5 minutes by vehicle depending on traffic from Agora Mall. NOTES. The day before the guest's arrival, you should send your IDs for adults of legal age. Via AIRBNB messaging.

Top guest favourite
Flat in Santo Domingo
5.0 out of 5 average rating, 24 reviews

Ensanche La Fé, National District

Stay in the heart of Santo Domingo in this spacious and modern apartment, ideal for families, groups of friends or business trips. Designed to offer you maximum comfort, it has air conditioning, Wi-Fi, private parking inside the building and an unbeatable location just a stone's throw from the main shopping centres, restaurants, main roads and the metro line.

Guest favourite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in Santo Domingo de Guzman
4.95 out of 5 average rating, 148 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Guest favourite
Flat in Santo Domingo
4.83 out of 5 average rating, 102 reviews

Studio apartment on the 17th floor, No Parking

Beautiful studio apartment, with one bedroom, ideal for sharing as a couple, located on the 17th floor, with social areas and all the necessary services for an excellent stay. The apartment has central air and does not have parking in the tower. It is located in the exclusive sector of Serralles, in the central part of Santo Domingo DN.

Superhost
A modern living area is highlighted by stylish light fixtures and large windows adorned with sheer drapes. The space features a circular mirror reflecting a decorative table with plants. Seating includes two contemporary chairs and a sofa, with a sleek console table against the wall.
Apartment in Santo Domingo
4.8 out of 5 average rating, 113 reviews

Luxury Apt - 1Bd + Pool + Downtown Santo Domingo

Don't miss the experience! Enjoy a stylish apartment in a central location, with all the comforts of a luxurious home, located in the exclusive area of Serralles; Pool (picuzzi), streaming services, among other amenities. Please read the rules!

Superhost
A bright living area features floor-to-ceiling windows that allow natural light to fill the room. A modern gray sofa with teal accent pillows is positioned around a sleek glass coffee table, enhancing the contemporary feel. Light-colored marble flooring adds a touch of elegance.
Flat in Santo Domingo
4.8 out of 5 average rating, 455 reviews

Modern Apartment in the City Center

Your family will be close to everything if you stay here! Very central and easily accessible accommodation in Naco. Your family will be close to everything when you stay here! Very central and easily accessible accommodation in Naco.

Popular amenities for Santo Domingo de Guzman holiday rentals