
Guest house holiday rentals in South Carolina
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in South Carolina
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

The James: “Tiny” Home b/w Downtown & Folly
The James is a unique 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02

Mountain Cabin on Creek at Jocassee Gorge.
Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

My Happy Place
This is a charming cottage with a pool and large outdoor area. It is located 3 minutes to both I26 and 526, a 10 minute drive to downtown Charleston and walking distance to North Charleston’s trendy, fun area. The Credit One Stadium on Daniel Island is a 10 minute drive, the Isle of Palms and Sullivans Island 15 minutes and North Charleston Colliseum 5 minutes. It is easy to get to all these places and there are many fun things to do in the Charleston/North Charleston/Daniel Island areas.

The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Buddy's Cottage near everything in Beaufort, SC
Who is Buddy? He was our black Labrador of 12 years. This well kept tiny home is adjacent to our main home and is private. It has 1 bedroom, 1 full bathroom, a sleeper sofa , 2 TV's, a full kitchen and all the amenities of home. Downtown Beaufort is 2 miles away, Parris Island is less than 5 miles away. In a quiet neighborhood. Are coming for a fishing trip and bringing your boat? Come stay with us , we have room for your boat. You can flush your engine and rinse your boat down.

Charming Waterfront Cottage with Beautiful Views.
This is a very comfortable guest cottage with one bedroom, bathroom with large shower, kitchenette, and living room. Guests may occasionally share the dock, screened-in porch, and swimming pool. A beach pass is provided for Hunting Island State Park as well as beach chairs and towels. "MarshSong" is an inspirational place for anyone who just wants to relax, or explore; a good central point for visiting Charleston and Savannah. Rest, relax, recharge - nap on a hanging bed; sleep well.

Lake front Lake Murray in the Heart of Lexington
Walk out onto Lake Murray in the heart of Lexington! From sunrise to sunset this home is perfect for that relaxing get away; a private beach is steps from your door, a dock to fish from, boat ramp to launch your lake toys, quite cove with beautiful wild life! As the owners we live in the upstairs of the home (completely securely separated) and are available if you need anything! We enjoy sharing this beautiful home with others! Please note the beach, dock and lake are shared spaces.

Horse Farm in Aiken, SC
Spacious, private guest house with views on a 17-acre entirely fenced horse farm located just 14 miles from Aiken, SC and 30 miles from Augusta, GA (Masters). Our equestrian community exudes southern charm; the perfect, peaceful retreat and horse country getaway. Near to historic Downtown Aiken & Hitchcock Woods. This family-friendly farm is ideal for short, extended or corporate stays. Have horses? There's a barn with 4 stalls and 7 fenced pastures for horse turnout. Separate fee.

Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.

Charming Hunt Country Cottage with Pool
Welcome to Camden Cottage! A peaceful guesthouse on 7.5 acres in Hunt Country. Walk to Camden Hunt Kennels, minutes to the SC Equine Park, and close to historic downtown. Cozy 1-bedroom with full kitchen, streaming TV (Netflix, Peacock, YouTube TV & more), and access to the pool and grill. Guests love the spotless, quiet setting and easy access to steeplechase races, Revolutionary War sites, festivals, golf, and Lake Wateree. Pets welcome ($35).
Popular amenities for guest house rentals in South Carolina
Family-friendly guest house rentals

Carriage House: Studio Bed & Bath - Pool & Hot Tub

Home on the farm

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

Greenville With A View!

Farm Stay w Gardens, Cute Animals, Firepit + Porch

1 BR Cottage/ Pool / Golf Cart/Near Beach

Camden Coach House Long term stay southern balance

Private-Lake getaway-7 mile view from dock
Guest house rentals with a patio

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

Shem Creek Cottage!

The Lodge at Pythian Park

Walk to restaurants! New, beautiful & clean home

Cary Lake Guesthouse - Slice of Heaven

Studio 77 in dt Charleston with bikes

Spacious Guest House in Mt Pleasant *10 min to dtn

The Little Cottage, Stateburg
Guest house rentals with a washing machine and dryer

Large Guesthouse with Private Dock & Marsh Views

Historic 19th Century Cabin/Guest House

Private 1/1 Old Mt Pleasant/Shem Creek Bungalow

The Wren Guest House

Beach, downtown, Alhambra Hall weddings so close!

Upscale Couple's Escape | Beach & Downtown CHS

1BR cottage~Charleston Peninsula~20min to beach

The Guest House By The River
Destinations to explore
- Cabin rentals South Carolina
- Motorhome rentals South Carolina
- Townhouse rentals South Carolina
- Farm stay rentals South Carolina
- Dome rentals South Carolina
- Family-friendly rentals South Carolina
- Tiny house rentals South Carolina
- Treehouse rentals South Carolina
- Serviced apartment rentals South Carolina
- Rentals with an accessible-height bed South Carolina
- Resort rentals South Carolina
- Beach apartment rentals South Carolina
- Nature eco lodge rentals South Carolina
- Loft rentals South Carolina
- Beach house rentals South Carolina
- Rentals with breakfast South Carolina
- Rentals with pools South Carolina
- Rentals with a sauna South Carolina
- Tent rentals South Carolina
- Rentals with an accessible-height toilet South Carolina
- House rentals South Carolina
- Luxury rentals South Carolina
- Boat rentals South Carolina
- Bed and breakfasts South Carolina
- Lakehouse rentals South Carolina
- Beachfront rentals South Carolina
- Rentals with lake access South Carolina
- Ski-in/ski-out rentals South Carolina
- Villa rentals South Carolina
- Cottage rentals South Carolina
- Boutique hotels South Carolina
- Aparthotel rentals South Carolina
- Rentals with a kayak South Carolina
- Hotel rooms South Carolina
- Holiday home rentals South Carolina
- Rentals with a hot tub South Carolina
- Rentals with beach access South Carolina
- Waterfront rentals South Carolina
- Campsite rentals South Carolina
- Hostel rentals South Carolina
- Pet-friendly rentals South Carolina
- Barn rentals South Carolina
- Flat rentals South Carolina
- Private suite rentals South Carolina
- Apartment rentals South Carolina
- Guest house rentals United States
- Things to do South Carolina
- Cooking South Carolina
- Wildlife South Carolina
- Food tours South Carolina
- Cultural tours South Carolina
- Outdoors South Carolina
- Landmarks South Carolina
- Tastings South Carolina
- Art workshops South Carolina
- Water sports South Carolina
- Things to do United States
- Dining United States
- Museums United States
- Shopping and fashion United States
- Cultural tours United States
- Architecture United States
- Workouts United States
- Art workshops United States
- Flying United States
- Wellness United States
- Food tours United States
- Wildlife United States
- Water sports United States
- Landmarks United States
- Performances United States
- Tastings United States
- Galleries United States
- Cooking United States
- Beauty United States
- Outdoors United States





