
Guest house holiday rentals in South Carolina
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Top-rated guest house rentals in South Carolina
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Private-Lake getaway-7 mile view from dock
Spacious two story guest house on a private road situated on Lake Hartwell. Use the double deck dock with 7 mile view for all day fishing, swimming or just relaxing. The guest house with central heating and air is fully furnished and has a fully equipped kitchen, wifi, 3 streaming flat screen tvs, two full baths, washer/dryer combo and a large attached deck. Owners live on property but in different residence. Outdoor cameras overlook parking area. Only reserved guests have property access.

Walk to restaurants! New, beautiful & clean home
Welcome to Curlew Corner! A new, private upstairs guesthouse in one of Charleston’s most desirable neighborhoods. With a king bed+sofa bed, this is an ideal spot for couples, friends, or small families looking for a getaway in a beautiful city! Location! The guesthouse is within walking distance to many eateries, bars, a music venue, cinema, farmer’s market, yoga studio, playground, boat landing, and beautiful water views. Close to downtown Charleston and Folly Beach, you can’t beat this spot!

The James: “Tiny” Home b/w Downtown & Folly
The James is a unique 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02

Mountain Cabin on Creek at Jocassee Gorge.
Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

Charming Waterfront Cottage with Beautiful Views.
This is a very comfortable guest cottage with one bedroom, bathroom with large shower, kitchenette, and living room. Guests may occasionally share the dock, screened-in porch, and swimming pool. A beach pass is provided for Hunting Island State Park as well as beach chairs and towels. "MarshSong" is an inspirational place for anyone who just wants to relax, or explore; a good central point for visiting Charleston and Savannah. Rest, relax, recharge - nap on a hanging bed; sleep well.

Lake front Lake Murray in the Heart of Lexington
Walk out onto Lake Murray in the heart of Lexington! From sunrise to sunset this home is perfect for that relaxing get away; a private beach is steps from your door, a dock to fish from, boat ramp to launch your lake toys, quite cove with beautiful wild life! As the owners we live in the upstairs of the home (completely securely separated) and are available if you need anything! We enjoy sharing this beautiful home with others! Please note the beach, dock and lake are shared spaces.

Horse Farm in Aiken, SC
Spacious, private guest house with views on a 17-acre entirely fenced horse farm located just 14 miles from Aiken, SC and 30 miles from Augusta, GA (Masters). Our equestrian community exudes southern charm; the perfect, peaceful retreat and horse country getaway. Near to historic Downtown Aiken & Hitchcock Woods. This family-friendly farm is ideal for short, extended or corporate stays. Have horses? There's a barn with 4 stalls and 7 fenced pastures for horse turnout. Separate fee.

Stunning Couples Cottage with Creek Dock!
You will fall in love with this stunning, newly-built guest cottage nestled under the canopy of a majestic 400-year-old live oak tree! Providing ultimate comfort, convenience and serenity, this is the perfect place to launch your Charleston adventure – 10 minutes to Shem Creek, & 15 minutes to Sullivan's Island or Downtown Charleston. PLUS, come enjoy our brand new dock on the creek! A picture-perfect spot to relax and enjoy the stunning Lowcountry scenery!

Greenville With A View!
ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Guesthouse Convenient to Charleston, Shem Creek, and Beaches
Relax in this separate guest home nestled in a well-established Lowcountry neighborhood. The ‘treehouse’ has an open-plan design with vaulted notched board ceilings, creating a feeling of light and space, with elegant furnishings throughout. The well-equipped kitchen and grill on the porch encourages intimate home cooking. We lived in this space before we moved into the main house, so we can attest to it being comfortable, and well maintained.
Popular amenities for guest house rentals in South Carolina
Family-friendly guest house rentals

Home on the farm

Carriage House: Studio Bed & Bath - Pool & Hot Tub

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Lizzi & Scott’sTiny Guest House secluded USC-Vista

Carriage House Suite on Lake Wylie

New Loft in Historic Summerville

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

My Happy Place
Guest house rentals with a patio

Restful Refuge

The Lodge at Pythian Park

The Little Cottage, Stateburg

Coastal Charm: Village Hideaway

The Dwelling Place: Just a mile from downtown TR

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

Cary Lake Guesthouse - Slice of Heaven

Aiken Barndominium/Studio Apt
Guest house rentals with a washing machine and dryer

Buddy's Cottage near everything in Beaufort, SC

Cozy Cottage w Games, Firepit, Grill, and More!

The Guest House By The River

The Cottage @JustA'MereLodge

Amazing Studio Guesthouse in COLA suburb.

Historic 19th Century Cabin/Guest House

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!

Large Guesthouse with Private Dock & Marsh Views
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