
Guest house holiday rentals in South Carolina
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Top-rated guest house rentals in South Carolina
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★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*
4.98 out of 5 average rating, 776 reviews
Farm Stay w Gardens, Cute Animals, Firepit + Porch
Welcome to the farm! This cute little farm studio is ready for your enjoyment! With a horse-front view and rows of flowers in sight, you will be sure to soak in all the feels of farm life, all while being close to West Ashley, 30 minutes from Downtown Charleston, and 35 min from beach access. Tucked in behind the hustle and bustle of city life, you can put your feet up and relax, walk the gardens, or check out the cute farm animals. Truly, this is a unique stay that you don't want to miss!
4.97 out of 5 average rating, 164 reviews
The James: “Tiny” Home b/w Downtown & Folly
The James is a unique 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02
4.98 out of 5 average rating, 268 reviews
Mountain Cabin on Creek at Jocassee Gorge.
Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.
4.91 out of 5 average rating, 453 reviews
Private 1/1 Old Mt Pleasant/Shem Creek Bungalow
Nestled in desirable Old Mt. Pleasant off Coleman Blvd, this quaint 1 bed/1 bath bungalow offers location and convenience. Minutes to Shem Creek and waterfront dining, just 3 miles from Sullivan's Island Beach. Enjoy sunsets from the nearby Pitt Street Bridge, or stroll just one block to bustling Coleman Blvd with restaurants, shops, and fitness. Three major grocery stores are <1 mile. Quiet, clean, and situated minutes to Downtown Charleston. STR Permit #ST260001 MP Bus Lic #BL-24-000053
4.97 out of 5 average rating, 624 reviews
Buddy's Cottage near everything in Beaufort, SC
Who is Buddy? He was our black Labrador of 12 years. This well kept tiny home is adjacent to our main home and is private. It has 1 bedroom, 1 full bathroom, a sleeper sofa , 2 TV's, a full kitchen and all the amenities of home. Downtown Beaufort is 2 miles away, Parris Island is less than 5 miles away. In a quiet neighborhood. Are coming for a fishing trip and bringing your boat? Come stay with us , we have room for your boat. You can flush your engine and rinse your boat down.
4.98 out of 5 average rating, 404 reviews
Lake front Lake Murray in the Heart of Lexington
Walk out onto Lake Murray in the heart of Lexington! From sunrise to sunset this home is perfect for that relaxing get away; a private beach is steps from your door, a dock to fish from, boat ramp to launch your lake toys, quite cove with beautiful wild life! As the owners we live in the upstairs of the home (completely securely separated) and are available if you need anything! We enjoy sharing this beautiful home with others! Please note the beach, dock and lake are shared spaces.
4.97 out of 5 average rating, 176 reviews
Horse Farm in Aiken, SC
Spacious, private guest house with views on a 17-acre entirely fenced horse farm located just 14 miles from Aiken, SC and 30 miles from Augusta, GA (Masters). Our equestrian community exudes southern charm; the perfect, peaceful retreat and horse country getaway. Near to historic Downtown Aiken & Hitchcock Woods. This family-friendly farm is ideal for short, extended or corporate stays. Have horses? There's a barn with 4 stalls and 7 fenced pastures for horse turnout. Separate fee.
4.98 out of 5 average rating, 164 reviews
River Retreat- Waterfront- Less than1 MI from PI
Escape to your own peaceful waterfront retreat less than a mile from Parris Island! This 3-bedroom, 2-bath river guest home sleeps up to 8 and features breathtaking water views, a private deep-water dock, screened porch, full kitchen, and washer/dryer. Watch the sunrise over the river, fish from the property, keep an eye out for feeding dolphins, or simply relax by the water. Perfect for Marine Corps graduation families, boating and fishing trips, or a relaxing Lowcountry getaway.
4.95 out of 5 average rating, 357 reviews
*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
LOCATION, LOCATION, LOCATION! Welcome to Persimmon Place, a new guesthouse in the heart of Old Village in Mt. Pleasant. Historic Old Village is one of Charleston's most beautiful neighborhoods, central to all Charleston has to offer. This 2BR 1 BA is the perfect spot for your Lowcountry visit. -Walk to Shem Creek with bars, restaurants, & water activities -Less than 4 miles(8 min drive)to Sullivan's Island Beach -5 miles(9 min drive)to downtown Charleston ST260213 BL20137971
4.96 out of 5 average rating, 196 reviews
Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.
4.9 out of 5 average rating, 1067 reviews
Stunning Couples Cottage with Creek Dock!
You will fall in love with this stunning, newly-built guest cottage nestled under the canopy of a majestic 400-year-old live oak tree! Providing ultimate comfort, convenience and serenity, this is the perfect place to launch your Charleston adventure – 10 minutes to Shem Creek, & 15 minutes to Sullivan's Island or Downtown Charleston. PLUS, come enjoy our brand new dock on the creek! A picture-perfect spot to relax and enjoy the stunning Lowcountry scenery!
4.98 out of 5 average rating, 287 reviewsPopular amenities for guest house rentals in South Carolina
Family-friendly guest house rentals

Scenic Loft in the Woods
4.97 out of 5 average rating, 381 reviews
Carriage House: Studio Bed & Bath - Pool & Hot Tub
4.95 out of 5 average rating, 786 reviews
Home on the farm
4.99 out of 5 average rating, 411 reviews
Studio Apt - (Pets/beach/pool/golf)
4.95 out of 5 average rating, 307 reviews
My Happy Place
4.93 out of 5 average rating, 207 reviews
Campus Cottage
4.98 out of 5 average rating, 123 reviews
Walk to restaurants! New, beautiful & clean home
4.98 out of 5 average rating, 124 reviews
Greenville With A View!
4.98 out of 5 average rating, 291 reviewsGuest house rentals with a patio

The Lodge at Pythian Park
5.0 out of 5 average rating, 151 reviews
Restful Refuge
4.99 out of 5 average rating, 181 reviews
Shem Creek Cottage!
4.96 out of 5 average rating, 153 reviews
Aiken Barndominium/Studio Apt
5.0 out of 5 average rating, 149 reviews
Spacious Guest House in Mt Pleasant *10 min to dtn
4.92 out of 5 average rating, 112 reviews
Hearts & Dreams Peaceful Family Retreat w/ pool
4.99 out of 5 average rating, 101 reviews
Studio 77 in dt Charleston with bikes
4.9 out of 5 average rating, 188 reviews
The Dwelling Place: Just a mile from downtown TR
4.99 out of 5 average rating, 121 reviewsGuest house rentals with a washing machine and dryer

Large Guesthouse with Private Dock & Marsh Views
4.98 out of 5 average rating, 253 reviews
Private-Lake getaway-7 mile view from dock
4.94 out of 5 average rating, 218 reviews
The Cottage @JustA'MereLodge
5.0 out of 5 average rating, 146 reviews
Camden Coach House Long term stay southern balance
4.91 out of 5 average rating, 387 reviews
Modern Cottage in Peaceful and Central Location
4.99 out of 5 average rating, 288 reviews
Amazing Studio Guesthouse in COLA suburb.
5.0 out of 5 average rating, 203 reviews
Cozy Park Circle, Charleston Guest House
4.93 out of 5 average rating, 462 reviews
The Guest House By The River
5.0 out of 5 average rating, 113 reviewsDestinations to explore
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