
Guest house holiday rentals in South Carolina
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Top-rated guest house rentals in South Carolina
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!
4.97 out of 5 average rating, 381 reviews
★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*
4.98 out of 5 average rating, 777 reviews
The James: “Tiny” Home b/w Downtown & Folly
The James is a unique 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02
4.98 out of 5 average rating, 268 reviews
Farm Stay w Gardens, Cute Animals, Firepit + Porch
Welcome to the farm! This cute little farm studio is ready for your enjoyment! With a horse-front view and rows of flowers in sight, you will be sure to soak in all the feels of farm life, all while being close to West Ashley, 30 minutes from Downtown Charleston, and 35 min from beach access. Tucked in behind the hustle and bustle of city life, you can put your feet up and relax, walk the gardens, or check out the cute farm animals. Truly, this is a unique stay that you don't want to miss!
4.97 out of 5 average rating, 164 reviews
My Happy Place
This is a charming cottage with a pool and large outdoor area. It is located 3 minutes to both I26 and 526, a 10 minute drive to downtown Charleston and walking distance to North Charleston’s trendy, fun area. The Credit One Stadium on Daniel Island is a 10 minute drive, the Isle of Palms and Sullivans Island 15 minutes and North Charleston Colliseum 5 minutes. It is easy to get to all these places and there are many fun things to do in the Charleston/North Charleston/Daniel Island areas.
4.93 out of 5 average rating, 207 reviews
Mountain Cabin on Creek at Jocassee Gorge.
Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.
4.91 out of 5 average rating, 453 reviews
The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.
4.99 out of 5 average rating, 468 reviews
Buddy's Cottage near everything in Beaufort, SC
Who is Buddy? He was our black Labrador of 12 years. This well kept tiny home is adjacent to our main home and is private. It has 1 bedroom, 1 full bathroom, a sleeper sofa , 2 TV's, a full kitchen and all the amenities of home. Downtown Beaufort is 2 miles away, Parris Island is less than 5 miles away. In a quiet neighborhood. Are coming for a fishing trip and bringing your boat? Come stay with us , we have room for your boat. You can flush your engine and rinse your boat down.
4.98 out of 5 average rating, 406 reviews
Lake front Lake Murray in the Heart of Lexington
Walk out onto Lake Murray in the heart of Lexington! From sunrise to sunset this home is perfect for that relaxing get away; a private beach is steps from your door, a dock to fish from, boat ramp to launch your lake toys, quite cove with beautiful wild life! As the owners we live in the upstairs of the home (completely securely separated) and are available if you need anything! We enjoy sharing this beautiful home with others! Please note the beach, dock and lake are shared spaces.
4.97 out of 5 average rating, 176 reviews
Horse Farm in Aiken, SC
Spacious, private guest house with views on a 17-acre entirely fenced horse farm located just 14 miles from Aiken, SC and 30 miles from Augusta, GA (Masters). Our equestrian community exudes southern charm; the perfect, peaceful retreat and horse country getaway. Near to historic Downtown Aiken & Hitchcock Woods. This family-friendly farm is ideal for short, extended or corporate stays. Have horses? There's a barn with 4 stalls and 7 fenced pastures for horse turnout. Separate fee.
4.98 out of 5 average rating, 165 reviews
*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
LOCATION, LOCATION, LOCATION! Welcome to Persimmon Place, a new guesthouse in the heart of Old Village in Mt. Pleasant. Historic Old Village is one of Charleston's most beautiful neighborhoods, central to all Charleston has to offer. This 2BR 1 BA is the perfect spot for your Lowcountry visit. -Walk to Shem Creek with bars, restaurants, & water activities -Less than 4 miles(8 min drive)to Sullivan's Island Beach -5 miles(9 min drive)to downtown Charleston ST260213 BL20137971
4.96 out of 5 average rating, 196 reviews
Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.
4.9 out of 5 average rating, 1068 reviewsPopular amenities for guest house rentals in South Carolina
Family-friendly guest house rentals

Carriage House: Studio Bed & Bath - Pool & Hot Tub
4.95 out of 5 average rating, 786 reviews
Home on the farm
4.99 out of 5 average rating, 411 reviews
Studio Apt - (Pets/beach/pool/golf)
4.95 out of 5 average rating, 309 reviews
Charming Hunt Country Cottage with Pool
4.99 out of 5 average rating, 182 reviews
Camden Coach House Long term stay southern balance
4.91 out of 5 average rating, 387 reviews
River Retreat- Waterfront- Less than1 MI from PI
4.95 out of 5 average rating, 357 reviews
Greenville With A View!
4.98 out of 5 average rating, 291 reviews
1 BR Cottage/ Pool / Golf Cart/Near Beach
4.96 out of 5 average rating, 118 reviewsGuest house rentals with a patio

Walk to restaurants! New, beautiful & clean home
4.98 out of 5 average rating, 125 reviews
Shem Creek Cottage!
4.96 out of 5 average rating, 154 reviews
The Little Cottage, Stateburg
4.98 out of 5 average rating, 159 reviews
Cary Lake Guesthouse - Slice of Heaven
4.83 out of 5 average rating, 164 reviews
Spacious Guest House in Mt Pleasant *10 min to dtn
4.92 out of 5 average rating, 113 reviews
Carriage House Suite on Lake Wylie
4.94 out of 5 average rating, 265 reviews
Studio 77 in dt Charleston with bikes
4.9 out of 5 average rating, 188 reviews
Aiken Barndominium/Studio Apt
5.0 out of 5 average rating, 149 reviewsGuest house rentals with a washing machine and dryer

Cozy Cottage w Games, Firepit, Grill, and More!
4.91 out of 5 average rating, 723 reviews
Private 1/1 Old Mt Pleasant/Shem Creek Bungalow
4.97 out of 5 average rating, 625 reviews
Large Guesthouse with Private Dock & Marsh Views
4.98 out of 5 average rating, 254 reviews
Charming Waterfront Cottage with Beautiful Views.
4.99 out of 5 average rating, 248 reviews
5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
4.98 out of 5 average rating, 180 reviews
Historic 19th Century Cabin/Guest House
4.93 out of 5 average rating, 754 reviews
Amazing Studio Guesthouse in COLA suburb.
5.0 out of 5 average rating, 203 reviews
Private-Lake getaway-7 mile view from dock
4.94 out of 5 average rating, 219 reviewsDestinations to explore
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