
Family-friendly rentals near Case Western Reserve University
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals near Case Western Reserve University
Guests agree: these stays are highly rated for location, cleanliness and more.

Cle Rocks-Little Italy! W Massage chair/Hot tub #2
Fall in love with this charming, newly updated 2-bedroom, 1-bath upper unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!
4.98 out of 5 average rating, 129 reviews
The Farmhouse - 1 Bdrm Apt in a Great Location
Welcome to this 2nd flr 1 bd/1 ba private apartment in a charming 1880s farmhouse located in a friendly walkable neighborhood. Full kitchen with all you need to make your own meals, washer/dryer and separate office inside the unit. Free off-street parking. You are only: 5 min walk to Starbucks, a variety of restaurants, bars, shops, trails 5-10 min drive to Cleveland Clinic, University Hospitals, Case Western, museums, parks, Little Italy and more 15 min drive to major attractions and Lake Erie
5.0 out of 5 average rating, 221 reviews
Little Italy Two Bedroom w/ Private Drive & Patio
Stay in the heart of Cleveland's historic Little Italy, one of the city's most vibrant and walkable neighborhoods. Restaurants, cafés, bakeries, galleries, and local markets are just steps away. Whether you're visiting Cleveland Clinic, University Hospitals, Case Western Reserve University, or exploring University Circle and Downtown Cleveland, you'll enjoy a stylish first-floor apartment with two private parking spaces, a fully equipped kitchen, a private patio, and room for up to six guests.
4.91 out of 5 average rating, 141 reviews
Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.
4.93 out of 5 average rating, 398 reviews
Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic
Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!
4.92 out of 5 average rating, 133 reviews
Mid-Century Modern Retreat in Little Italy
Nestled in the vibrant yet peaceful and safe Little Italy neighborhood of Cleveland, this newly remodeled Mid-Century Modern style 2bed/1bath Lower unit is within walking distance to the best Cleveland has to offer. Enjoy a stroll to Case Western Reserve University, University Circle, the Cleveland Museum of Art, Cleveland Botanical Garden, and more. Discover local shops, bakeries, and renowned restaurants that give Little Italy its charm. The RTA redline station is a five minute walk.
4.96 out of 5 average rating, 53 reviews
Gem in the heart of Little Italy! 3BR-DN
Enjoy your stay at this centrally located - lower unit- in a two-family home in Little Italy. Apartment is complete with a well-equipped kitchen. The living room includes comfortable seating for 6, a smart TV, 3 poufs & coffee table - so that ALL may rest their feet from a long day, modern furnishings and a laundry room. Each bedroom includes USB plugs in the lamps, alarm clocks with sound machines, blackout curtains, ceiling fans, Smart TVs, "ultra-quiet" ACs, desk, chair & mirror.
4.98 out of 5 average rating, 100 reviews
Private Victorian suite with two rooms and a bath
You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.
4.96 out of 5 average rating, 551 reviews
2BR in Little Italy, 5 min walk to Case & UH
Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.
4.83 out of 5 average rating, 130 reviews
Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.
4.98 out of 5 average rating, 559 reviews
Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled stay in this boho-chic apartment in the heart of Little Italy. Exposed brick, hardwood floors, and warm wooden furnishings create a comfortable and inviting space. Relax on the sofa, enjoy a meal in the cozy kitchen, and explore nearby restaurants, cafés, and shops—all within walking distance.The apartment is located on the second floor and requires one flight of stairs (17 steps). Free on-site parking is available for one car.
4.98 out of 5 average rating, 107 reviews
La Rapsodia in Blu Della Little Italy *family run*
Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!
4.98 out of 5 average rating, 108 reviewsPopular amenities for family-friendly rentals near Case Western Reserve University
Family-friendly home rentals with a hot tub

HotTub GameRoom Fenced EV PetsOK KingBeds KidLoft
5.0 out of 5 average rating, 135 reviews
Hot Tub! Ohio City Modern Luxury · 2 King Beds
4.94 out of 5 average rating, 125 reviews
Private 2 Level Apartment with Hot Tub in Tremont
4.88 out of 5 average rating, 525 reviews
Planes, Trains and Automobiles
4.92 out of 5 average rating, 158 reviews
Unique Ohio City Getaway | Hot Tub + Pool Table
4.88 out of 5 average rating, 154 reviews
Westside Warehouse-Hot Tub/GameRM/PoolTable & More
4.88 out of 5 average rating, 289 reviews
Groovy Cedar Chalet Forest View
4.95 out of 5 average rating, 130 reviews
Lux Penthouse Downtown Cleveland - Rooftop Hot Tub
4.9 out of 5 average rating, 131 reviewsFamily- and pet-friendly home rentals

Charming Coventry Village Hampshire Rd (Lower)
4.82 out of 5 average rating, 358 reviews
Gallery House | Near Clinic + Museums
4.82 out of 5 average rating, 245 reviews
Cozy house near Lake Erie, 10 minutes to Downtown.
4.97 out of 5 average rating, 345 reviews
Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #7
4.94 out of 5 average rating, 66 reviews
Cozy Comfortable Home close to Cleveland Clinic
4.93 out of 5 average rating, 61 reviews
Historic Carriage House | Cleveland Heights
4.91 out of 5 average rating, 82 reviews
Wizards- Theater Hot Tub Pickleball Poker BBQ King
5.0 out of 5 average rating, 4 reviews
Cozy Home Near Major Hospitals & Universities
4.9 out of 5 average rating, 50 reviewsFamily-friendly home rentals with a pool

Stylish Chic Downtown Apartment
4.92 out of 5 average rating, 106 reviews
Luxe Lil' Italy 2BR | Sleeps 6 | Free Parking+Gym
4.79 out of 5 average rating, 39 reviews
Pool • Steps to Concert Venues • Stadiums • Views
5.0 out of 5 average rating, 15 reviews
Central Flat: Indoor Pool, Rooftop, Gym
4.88 out of 5 average rating, 32 reviews
Luxury Spa+Theater+Gameroom | CasaMora
5.0 out of 5 average rating, 70 reviews
Luxury Apt w/ Rooftop Pool, Hot Tub & Skyline View
4.95 out of 5 average rating, 56 reviews
Alizée | Stylish Studio Retreat Near Downtown CLE
4.91 out of 5 average rating, 33 reviews
Chic Downtown Living—Sleek Apt Near Attractions
4.84 out of 5 average rating, 31 reviewsFamily-friendly home rentals with wifi

Cozy Condo l Minutes from Cleveland Clinic
4.69 out of 5 average rating, 45 reviews
Green Historic House by Cle Clinic, CWRU, Museums
4.88 out of 5 average rating, 41 reviews
The Onyx Suite Mins From Cleveland Clinic, VA & UH
5.0 out of 5 average rating, 15 reviews
Easy Check-In 4 mins Cleveland Clinic CWRU Parking
5.0 out of 5 average rating, 20 reviews
Sleeps 3 | Downtown & Museums Nearby
4.8 out of 5 average rating, 25 reviews
Cleveland Clinic, 5 minutes from: South Suite
4.86 out of 5 average rating, 77 reviews
Relax at New Home & Walk to Cle Clinic
4.98 out of 5 average rating, 52 reviews
Contemporary Cedar-Lee Walkup
4.92 out of 5 average rating, 84 reviewsQuick stats about family-friendly rentals near Case Western Reserve University

Total holiday rentals
Explore 40 holiday rentals in Case Western Reserve University

Nightly prices starting at
Case Western Reserve University holiday rentals start at £15 per night before taxes and fees

Verified guest reviews
Over 1,170 verified reviews to help you choose

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
40 of Case Western Reserve University holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Case Western Reserve University rentals

4.8 Average rating
Case Western Reserve University stays are highly rated by guests – averaging 4.8 out of 5!
Destinations to explore
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Gervasi Vineyard
- Headlands Beach State Park
- Cleveland Browns Stadium
- Cleveland Metroparks Zoo
- Mosquito Lake State Park
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- Laurentia Vineyard & Winery
- The Arcade Cleveland
- Cleveland Museum of Art
- Huntington Convention Center of Cleveland
- Crocker Park
- Debonné Vineyards
- Edgewater Park Beach
- JACK Cleveland Casino
- Rocky River Reservation
- Cleveland Museum of Natural History
- Greater Cleveland Aquarium





