
Places to stay near Cleveland Museum of Natural History
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Top-rated holiday rentals near Cleveland Museum of Natural History
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New Cleveland Apt: Little Italy! Massage&Hot tub!
Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!
4.98 out of 5 average rating, 325 reviews
In the heart of Little Italy! Free Parking! 3BR-UP
Enjoy your stay at this centrally located - upper unit- in a two-family home in Little Italy. Apartment is complete with a well-equipped kitchen. The living room includes comfortable seating for 6, a smart TV, 3 poufs & coffee table - so that ALL may rest their feet from a long day, modern furnishings and a washer/dryer/linen closet. Each bedroom includes USB plugs in the lamps, alarm clocks with sound machines, blackout curtains, ceiling fans, Smart TVs, "ultra-quiet" ACs, desk, chair & mirror.
5.0 out of 5 average rating, 107 reviews
Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled experience at this boho-chic apartment in the heart of Little Italy. Exposed brick walls, hardwood floors, and wooden furnishings combine to give this apartment a boho-chic aesthetic. Enjoy dinner in the cozy kitchen and watch TV while relaxing on the comfortable sofa. One flight of stairs is leading up to the second floor (17 steps)The unit is on a quiet side street in walking distance to the heart of Little Italy (restaurants,cafes, shops).Free parking on premises(1car)
4.98 out of 5 average rating, 105 reviews
Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.
4.93 out of 5 average rating, 391 reviews
Little Italy Two Bedroom w/ Private Drive & Patio
Stay in the heart of Cleveland's historic Little Italy, one of the city's most vibrant and walkable neighborhoods. Restaurants, cafés, bakeries, galleries, and local markets are just steps away. Whether you're visiting Cleveland Clinic, University Hospitals, Case Western Reserve University, or exploring University Circle and Downtown Cleveland, you'll enjoy a stylish first-floor apartment with two private parking spaces, a fully equipped kitchen, a private patio, and room for up to six guests.
4.91 out of 5 average rating, 134 reviews
Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic
Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!
4.92 out of 5 average rating, 129 reviews
Mid-Century Modern Retreat in Little Italy
Nestled in the vibrant yet peaceful and safe Little Italy neighborhood of Cleveland, this newly remodeled Mid-Century Modern style 2bed/1bath Lower unit is within walking distance to the best Cleveland has to offer. Enjoy a stroll to Case Western Reserve University, University Circle, the Cleveland Museum of Art, Cleveland Botanical Garden, and more. Discover local shops, bakeries, and renowned restaurants that give Little Italy its charm. The RTA redline station is a five minute walk.
4.96 out of 5 average rating, 50 reviews
Cozy Condo l Minutes from Cleveland Clinic
Our apartment is ideally located near Cleveland Clinic, making it perfect for medical professionals, patients, and families. You’ll also be minutes from the Health Education Campus, Case Western Reserve University, University Hospitals, and the museums of University Circle. Enjoy a short drive to the charming Little Italy neighborhood, filled with authentic Italian restaurants, cafés, and bakeries, while downtown Cleveland is just 5 miles away for dining and entertainment.
4.68 out of 5 average rating, 44 reviews
Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.
4.98 out of 5 average rating, 555 reviews
Green Historic House by Cle Clinic, CWRU, Museums
Entire private house near Cleveland Clinic, ideal for families, travel nurses, and business travelers. 10-min walk to Cleveland Clinic with quick access to University Hospitals, Case Western, Little Italy, museums, and downtown Cleveland. 3BR house with full kitchen, washer/dryer, free parking, fast Wi-Fi, private backyard, and self check-in. Quiet, clean space for short or extended stays, including monthly stays. Blue house next door also available.
4.87 out of 5 average rating, 39 reviews
Wade Manor-GameRoom, Gym, Office & Fenced Backyard
Experience the best of both worlds with our modern-classic styled Airbnb located just a stone's throw away from University Circle and Cleveland Clinic Main campus. Our beautifully designed space boasts a perfect blend of contemporary and traditional elements that will make your stay a unique and memorable one. Come explore the vibrant neighborhood and immerse yourself in its cultural and culinary delights. We cannot wait to host you!
4.78 out of 5 average rating, 214 reviews
Steps to Cleveland Clinic | 5BR ADA-Friendly Home
🏡 5 bedrooms • 7 beds • 3 bathrooms • Sleeps 12 ♿ ADA-accessible bedroom + bathroom w/ramp to front door 🐾 Pet-friendly • Attached 2-car garage 🍳 Fully equipped kitchen • Dining & living room for gatherings 🛋 Designer-curated décor • Themed bedrooms 📍 Steps from Cleveland Clinic Main Campus Spacious, stylish, and perfectly located — this home is ideal for families, medical professionals, and groups visiting Cleveland.
4.96 out of 5 average rating, 135 reviewsPopular amenities for holiday rentals near Cleveland Museum of Natural History
Other top sights near Cleveland Museum of Natural History
Cleveland Clinic - Main Campus Emergency Room
112 locals recommend
Cleveland Museum of Art
577 locals recommend
Case Western Reserve University
57 locals recommend
Cleveland Botanical Garden
242 locals recommend
Cleveland Museum of Natural History
236 locals recommend
Severance Music Center
106 locals recommend
Apartment rentals with wifi

Cozy Condo
4.97 out of 5 average rating, 175 reviews
Lux Penthouse Downtown Cleveland - Rooftop Hot Tub
4.9 out of 5 average rating, 128 reviews
Awesome 2 Bedroom Unit w/ Hot Tub and Fenced Yard
4.91 out of 5 average rating, 436 reviews
Luxury Top Floor Condo with a View
4.92 out of 5 average rating, 136 reviews
A Cleveland Modern & Historic Apartment 106-1
4.96 out of 5 average rating, 136 reviews
Bright and Hip 2BR Condo in Heart of Ohio City
4.94 out of 5 average rating, 231 reviews
Chic home near Cleveland airport
4.89 out of 5 average rating, 197 reviews
Cozy Downtown Modern Condo in the Heart of it all
4.81 out of 5 average rating, 359 reviewsFamily-friendly house rentals

House in the Heights 4br close to Downtown
4.98 out of 5 average rating, 143 reviews
Unique Home in Cleveland Heights
4.97 out of 5 average rating, 105 reviews
Cozy on Crawford | New 3BR 1st Floor Suite near CC
4.99 out of 5 average rating, 80 reviews
Baseball Themed Hot Tub, Poker, Pool, Yard, BBQ
5.0 out of 5 average rating, 36 reviews
Cozy Comfortable Home close to Cleveland Clinic
4.93 out of 5 average rating, 60 reviews
Luxury 3BR- Game Room CLE Clinic UC & Little Italy
4.95 out of 5 average rating, 41 reviews
Group Stay Near Cleveland Clinic
4.85 out of 5 average rating, 74 reviews
Stay at Supreme!
4.86 out of 5 average rating, 22 reviewsApartment rentals with air conditioning

2BR in Little Italy, 5 min walk to Case & UH
4.83 out of 5 average rating, 128 reviews
Renovated Historic Loft Apartment
4.9 out of 5 average rating, 148 reviews
Stylish Studio | Near Downtown CLE | Trail Access
4.92 out of 5 average rating, 194 reviews
Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #7
4.94 out of 5 average rating, 66 reviews
Sleeps 3 | Downtown & Museums Nearby
4.83 out of 5 average rating, 23 reviews
Walk to Cleveland Clinic | Modern 1BR | Parking
5.0 out of 5 average rating, 11 reviews
Walkable Little Italy Gem w/ King Bed | Near CWRU
4.84 out of 5 average rating, 85 reviews
Modern Univ Circle Suite | UH/CWRU | Gated Parking
4.95 out of 5 average rating, 56 reviewsOther great holiday rentals near Cleveland Museum of Natural History

The Lake House
4.87 out of 5 average rating, 83 reviews
New Luxury Studios | Walk to Cleveland Clinic
4.84 out of 5 average rating, 137 reviews
The Cleveland Coop
4.79 out of 5 average rating, 402 reviews
3 min Drive to Cle Clinic Free Parking
4.89 out of 5 average rating, 141 reviews
Spacious Home Near Downtown, Little Italy, Clinic
4.83 out of 5 average rating, 259 reviews
Modern Loft | Walk to Cleveland Clinic, UH & CWRU
4.63 out of 5 average rating, 8 reviews
Earthy inspired neutral Parisian home
4.86 out of 5 average rating, 69 reviews
*CONVENIENT!>next to CWRU, UH, CC!
4.58 out of 5 average rating, 113 reviewsDestinations to explore
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Gervasi Vineyard
- Headlands Beach State Park
- Cleveland Browns Stadium
- Case Western Reserve University
- Cleveland Metroparks Zoo
- Mosquito Lake State Park
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- Laurentia Vineyard & Winery
- The Arcade Cleveland
- Cleveland Museum of Art
- Huntington Convention Center of Cleveland
- Crocker Park
- Edgewater Park Beach
- Debonné Vineyards
- JACK Cleveland Casino
- Rocky River Reservation
- Stan Hywet Hall and Gardens





