Apartment holiday rentals in Santo Domingo de Guzman

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santo Domingo de Guzman

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite

Apartment

4.96 out of 5 average rating, 156 reviews

ღ Premium Location: KING Bed & Rooftop Bella Vista

Whether you're seeking relaxation, aiming for a productive retreat, eager for urban adventures or just scaping the cold, our Airbnb is your ideal destination. Come in and make yourself at home! 🌟Don't miss out on our unbeatable rates, reserve your spot now Located 3 blocks from Downtown Center Mall, you'll be immersed in a vibrant neighborhood with top-notch restaurants, bars, entertainment, and shopping all within reach. Experience the charm of Santo Domingo right from the center of it all.

Guest favourite

Apartment

4.9 out of 5 average rating, 107 reviews

Beautiful Modern Penthouse close to Zona Colonial.

Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 4 smart TVs and much more. Smart lock for easy check-in.

Guest favourite

Apartment

4.91 out of 5 average rating, 122 reviews

Luxe 2br-Naco- w/Fireplace-2 Pools

Updated:kitchen Color!! Updated: NOW TWO KING BEDS!! Luxury apartment with high-end appliances that includes everything you could ever want or need. Large and spacious and situated in premium location. Top-of-the-line appliances and housewares, on-site parking and countless amenities which include. TwoLarge Pool with BBQ Area. Full Gym and children play area. Recreational room. Bar.Lounge area. Fast Wifi Netflix,Amazon . Air Conditioned Bedrooms and Ceiling Fans. Samsung Washer and dryer.

Guest favourite

Apartment

4.98 out of 5 average rating, 117 reviews

2 Bedroom | 2.5 Bth 🏊 Pool 🏋️Gym 🏠 CONDO📍SD

LOOKING 👀 FOR A GREAT 😊 AIRBNB EXPERIENCE, well Come make the most out of your trip at my beautiful, peaceful & unique condominium. Located in one of the most pristine & safe area in the capital of Dominican Republic. You will be close distance to some of the most exquisite 5 star restaurants in the capital, as well as the Plaza Central, Agora Mall & many more well known places of entertainment. What are you waiting for, book your amazing trip at my condominium. Your home away from home! 😊

Guest favourite

Apartment

4.89 out of 5 average rating, 102 reviews

Lovely & ComfyCondo - Perfect Location | Fast WiFi

Experience the best of Santo Domingo from our fully air-conditioned apartment in the prestigious Piantini neighborhood. Perfect for couples or solo travelers, our cozy space features a comfortable living room with a flat-screen TV and a bedroom with a TV. With its unbeatable location just steps away from high-end malls and top-rated restaurants, this is the perfect home base for exploring the city's top attractions. Book now for a memorable stay in Santo Domingo! Read more below!

Guest favourite

Apartment

4.97 out of 5 average rating, 129 reviews

Central 2 room apartment with rooftop and picuzzi.

We offer you a beautiful, cozy apartment, centrally located, with free and secure parking. Rooftop with picuzzi with beautiful views of the sea and the city. Prime location in Gazcue, a few steps from the Plaza de la Cultura, museums, theaters, bars, restaurants, supermarkets, medical centers, pharmacies, a few minutes from the colonial zone, shopping centers, universities and banks. The apartment is totally well equipped with everything you need for a comfortable and pleasant stay.

Guest favourite

Apartment

4.9 out of 5 average rating, 146 reviews

Luxury, Upscale City Center, Jacuzzi, Great Views.

Beautiful, Upscale city center one-bedroom condo, very well appointed with all the essentials you need for short or long stays; fully stacked kitchen, fast Wi-Fi, full AC… Amazing roof-top social area with pool, Jacuzzi, lounge area and more… Located in the heart of Piantini, near restaurants, supermarkets and shopping malls. This apartment is excellent for business travelers, couples or just for tourism to get to know the beautiful and exiting city of Santo Domingo.

Guest favourite

Apartment

4.85 out of 5 average rating, 130 reviews

Beyond chic 3 Bedroom with Pool

Alejandro’s place is located in one of the most popular areas of Santo Domingo central (Zona Colonial) making things easy to plan your visit, Fully renovated for 2025 .Near to all historical areas and walking distances to the best restaurants and Bars of Santo Domingo City . five minutes walking distances to Christopher Columbus House, Near to Columbus Park, Fortaleza Ozama, Columbus Lighthouse, Basilica Cathedral , museum of the royal Houses, Restaurants and more .

Guest favourite

Apartment

4.96 out of 5 average rating, 102 reviews

City Center | Spacious | 2BR | Gym | Grill & Patio

Brand new 2BR, 2.5BA condo conveniently located in the heart of Santo Domingo. Walkscore ranks our condo location 97 out of a 100, a "Walker's Paradise" !!!!! Walking distance to Acropolis Center, Blue Mall, Supermarkets, Restaurants, and Avenida Winston Churchill WiFi | Top-rated, high-end, hand tofted, organic mattresses | High-end KitchenAid appliances | High-end furniture | 4K Smart HDTVs (58" & 55") | 3 Air conditioning (Bedrooms | Dining/Kitchen)

Guest favourite

Apartment

4.79 out of 5 average rating, 226 reviews

Stylish Apt. , VIP Location, Rooftop Pool-Seaview

Apartamento ubicado en la zona mas exclusiva y centrica de Sto Domingo (Piantini) -Ideal para viajeros refinados, profesionales y viajeros de negocios -Eres bien recibido con su pareja - Facil y rapido check in , out - Excelente y amigable servicios de conserjería de alto nivel (24h) - A escasos metros caminando se encuentra los restaurantes mas exclusivos de Sto Domingo , Pepperoni , Dolceri, Don Pepe, Loreta

Guest favourite

Apartment

4.96 out of 5 average rating, 115 reviews

LUXURY CONDO 📍2BR, , CITY CENTER 🌇 POOL & GYM

this elegant accommodation is ideal for family trips, located in one of the most important areas of santo domingo. with the highest quality standards, modern and elegant decoration to make you feel at home.this unique place has a style all its own. nearby the most exclusive restaurants,bars and night clubs. conveniently located and surrounded by shopping mall, supermarkets and many other businesses.

Superhost

Apartment

4.81 out of 5 average rating, 134 reviews

Prime Spot | Near It All | 2+ Guests on Request

20 minutes from airport,30 minutes from Boca Chica Beach, our cozy apartment is ideally located 5 minutes from the historic Zona Colonial. Explore markets, dine at local restaurants, visit museums, and enjoy events nearby. With supermarkets and public transport at your fingertips. Relax in comfort with air conditioning in every bedroom and the living room, perfect for unwinding after a busy day.