
Guest house holiday rentals in Distrito Nacional
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Top-rated guest house rentals in Distrito Nacional
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Private Cozy Apartment Studio
One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.
4.92 out of 5 average rating, 51 reviews
Centric & Elegant Studio/Colonial Style/Ample Yard
Unique studio within a renovated property. Large patio with fence and electric gate. Ideally located, 2 miles away from the Colonial Zone, 3 from Downtown. Hospital, Laundry, Sea View within 2 blocks. Supermarket, restaurants, museums within 1 mile. Less than 0.5 miles away from 2 subway stations. Fast Wifi (100+ Mbps). Smart speaker can control lights, AC, adjust temperature or play your favorite music. 4K TV w/swivel base, includes YouTube, Netflix, PrimeVideo, Disney and Star+. Queen bed.
4.9 out of 5 average rating, 71 reviews
Giuliela Boutique Stay – Entire Residence
A private sanctuary where history meets intention. This exclusive stay includes both Luna and Sole Suites within GIULIELA, a beautifully restored 1930s residence in Gazcue. While guests enjoy their own private accommodations, my family and I reside in the main house, allowing us to offer personalized local recommendations, and attentive hospitality. Curated design, timeless charm, and a touch of quiet luxury create an intimate experience that blends authentic local living with refined comfort.

VillaMella Oasis 2bedroom2bathroom Patio Hot Water
Welcome to your Oasis in Villa Mella. Relax in comfort and luxury with a second-floor-level, 2 queen beds, 2 private baths, and a fold-out sofa. Enjoy A/C, hot water, fast WIFI, and 3 Roku TVs with Netflix. Secure smart lock entry and 24/7 on-site staff that will ensure peace of mind. Just a 5-minute walk from the Gregorio Gilbert Metro station. Bring the whole family to this great place with lots of room for fun. Need a driver? We've got you covered. Let us melt your stress away! Book now!
4.92 out of 5 average rating, 13 reviews
Vintage-Modern 2floor GuestHouse
NEWLY REDESIGNED!! Opening the doors of our beautiful historical building to be part of your memorable experiences. One of a kind space with optimum city location. Each special suite is equipped with their unique private bathroom. Free Dominican coffee & free WI-FI in the whole building. Private entrances, several terraces, & many more spaces available for you to access. Centrally located in Santo Domingo with all types of attractions; variety of restaurants & markets really close by.

Casa en Villa Marina, Los Ríos de Santo Domingo
The House is new and is located in the Residential Villa Marina, a quiet, noiseless and safe place, although just two blocks from 3 major avenues, Duarte Highway and John F. Fennedy, in addition to Av. de los Próceres. It is also close to the train or metro station and bus terminal. It is also very close to a tourist place much visited for its natural beauty, is the Botanical Garden, a beautiful national natural park. The price is per room, per person, with options.

Cozy apartment for work / holidays.
Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.
4.97 out of 5 average rating, 89 reviews
Guest House in the city/pool/USA Embassy
You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.
4.95 out of 5 average rating, 20 reviews
Your little corner of peace in SDO
Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.
4.92 out of 5 average rating, 25 reviews
Cozy Separate Room in Santo Domingo Colonial
Book – Private Studio with Shared Patio. Comfortable - spacious, close to colonial zone, presidential palace, independence park, Malecon. First city in the American continent. Most touristic area of Santo Domingo. Most tourist area of Santo Domingo! Great for sightseeing
4.65 out of 5 average rating, 152 reviews
Villas Na’ Keys
Discover a unique retreat where comfort, privacy and beauty come together to create an unforgettable experience. Our villa has been carefully designed to offer a cosy and elegant atmosphere, ideal for both relaxing getaways and special moments with family and friends.
4.0 out of 5 average rating, 5 reviews
Your cozy little guest house
Enjoy your stay! Comfortable and pleasant guest house on the ground floor (no stairs, no elevators) cool patio, in the city center, near the Quisquella Stadium, Plaza de la Salud, shopping malls, etc.
4.87 out of 5 average rating, 62 reviewsPopular amenities for guest house rentals in Distrito Nacional
Family-friendly guest house rentals

Cozy, quiet, safe
4.78 out of 5 average rating, 37 reviews
room with personal bed
4.52 out of 5 average rating, 23 reviews
3 Private Room El Vergel
4.89 out of 5 average rating, 9 reviews
Stay at Pepa's
4.85 out of 5 average rating, 13 reviews
Wi-Fi, TV, toilet, air conditioning, refrigerator, no. 3 and 4
4.6 out of 5 average rating, 10 reviews
El Conde Colonial Area + Private Bathroom + Kitchenette
New place to stay
view of the Caribbean Sea
New place to stay
Mega center
Guest house rentals with a patio

Charming Shelter - Suite #5
5.0 out of 5 average rating, 4 reviews
Beautiful room in the Colonial area
4.64 out of 5 average rating, 83 reviews
Nochebuena Room at Akaiah Guest House.
4.67 out of 5 average rating, 6 reviews
Room with private bathroom near the colonial area
New place to stay
EatWise GuestHouse • Queen Room •

U.S. Embassy Stay Inn
3.67 out of 5 average rating, 3 reviews
Rooms in the Colonial Zone

Budget room for tourists and backpackers
3.33 out of 5 average rating, 3 reviewsGuest house rentals with a washing machine and dryer

Secure★DCGen★Full Kitchen★100+Mbs★Comfy Bed★W/D
4.82 out of 5 average rating, 224 reviews
Guestroom Deluxe in Santo Domingo
New place to stay
ZONA Colonial Walking distance B
4.63 out of 5 average rating, 16 reviews
Bedroom inside apartment
4.53 out of 5 average rating, 19 reviews
Family-friendly and comfortable

Luxury apartment in Santuario

ZONA COLONIAL*walking distance A
4.68 out of 5 average rating, 250 reviewsDestinations to explore
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