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House holiday rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total holiday rentals

    Explore 100 holiday rentals in Mytilini

  • Nightly prices starting at

    Mytilini holiday rentals start at £15 per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    100 of Mytilini holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests – averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home
4.89 out of 5 average rating, 101 reviews

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

Top guest favourite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home
4.98 out of 5 average rating, 88 reviews

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

Guest favourite
A modern villa is set against a night sky, with soft illumination highlighting its sleek design. The stone exterior is contrasted by bright lighting, creating a welcoming entrance. Lush greenery frames the scene, providing a touch of nature to the contemporary architecture.
Home
5 out of 5 average rating, 14 reviews

Pieres Blanches Recidences

Ανακαλύψτε την απόλυτη εμπειρία διαμονής 1,5 χιλιόμετρο απο το κέντρο της πόλης της Μυτιλήνη. Με κομψό σχεδιασμό και μοντέρνες ανέσεις, οι τρεις αυτόνομες μονοκατοικίες μας, των 120 τ.μ. η καθεμία, σας προσκαλούν να απολαύσετε την ηρεμία και την ομορφιά του νησιού. Κάθε βίλλα διαθέτε τρία άνετα υπνοδωμάτια, δύο μπάνια, ευρύχωρο σαλόνι, σοφίτα, πλήρως εξοπλισμένη κουζίνα και ιδιωτική πισίνα για να δροσιστείτε και να απολαύστε τον ήλιο στην άνεση της δικής σας πισίνας.

Top guest favourite
A logo for '4 Seasons Guest Room Mytilene' is displayed, featuring a stylized house silhouette against four colorful panels representing the seasons: green leaf, yellow sun, red maple leaf, and blue snowflake. The name is prominently presented in a bold font below.
Home
4.98 out of 5 average rating, 60 reviews

4 seasons

Fully furnished 38 sq.m. apartment, ideal for up to 2 guests — an ideal choice for couples or travelers seeking comfort and tranquility. The apartment is located in the traditional neighborhood of Synoikismos, very close to all local businesses (pharmacy, mini market, bakery, greengrocer, pastry shop, etc.) and just a few minutes away from the city center. It is an ideal choice for either a short getaway or a longer stay.

Top guest favourite
A niche with a wooden ledge showcases two woven baskets, providing storage for items. The soft lighting enhances the neutral tones of the walls, leading to a spacious area beyond. Visible are elements of a minimalist design, contributing to a functional living space.
Home
4.92 out of 5 average rating, 38 reviews

G&D studio

Ο χώρος μας D&G studio είναι ιδανικός για 2 άτομα με δυνατότητα φιλοξενίας και για 1 ακομη βρίσκεται στο δεύτερο επίπεδο ενός συγκροτήματος στην πανέμορφη περιοχή Άγιου Ισιδώρου στη πόλη Πλωμάρι Λέσβου .Στο μπαλκόνι διαθέτει τραπεζαρία όπου μπορείτε να απολαύσετε τον καφέ σας είτε ένα ποτήρι κρασί με θέα το Αιγαίο πέλαγος και το υπέροχο ηλιοβασίλεμα ζώντας την απόλυτη χαλάρωση καθώς η περιοχή προσφέρετε γιαυτο

Guest favourite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home
4.81 out of 5 average rating, 109 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

Guest favourite
A spacious sleeping area features a wooden platform bed with light blue bedding, complemented by two decorative pillows. The stone walls add a rustic touch, while large windows provide natural light. A red area rug enhances the room’s warmth and comfort.
Home in Ayvacık
4.95 out of 5 average rating, 127 reviews

Babakale Cumbalı Ev-Entire Stone House w/ sea view

T.C. Kültür ve Turizm Bakanlığı, Turizm Amaçlı Kiralanan Konut İzin Belgesi No: 17-626 Cumbalı taş evimiz 55 m2 kapalı alan 100 m2'den fazla kendine ait bahçesi ile iki kişinin konaklayabilmesi için tasarlanmıştır. Gün boyu evimizin hemen her yerinden Ege denizi manzarasının keyfini sürebilir; ve mangal eşliğinde ağaçlar altında enfes manzara ile akşam yemeğinin keyfini çıkarabilirsiniz

Top guest favourite
Home
5 out of 5 average rating, 18 reviews

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

Guest favourite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home
4.92 out of 5 average rating, 26 reviews

Pelagia's House

Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

Guest favourite
Home
5 out of 5 average rating, 15 reviews

D. Bernardaki Garden House

Welcome to Bernardaki Garden House! Nestled in a traditional neighbourhood, our professionally designed apartment offers the perfect blend of modern comfort and timeless charm in the heart of Mytilene. Why does our proposal stand out among the options in the whole Mytilene? There's a reason, and we're eager to share it with you!

Guest favourite
An open-plan living area features a light stone wall alongside a modern kitchen. A spacious beige sofa is complemented by two cozy poufs and a round area rug. Natural light filters through large windows, illuminating the space, while a dining table with wooden chairs is positioned nearby.
Home
4.86 out of 5 average rating, 14 reviews

Aeolian Apartment

Discover the perfect blend of comfort, design, and convenience in our beautifully designed 2-bedroom home, just a 5-minute walk from the vibrant city center of Mytilene. Nestled in a peaceful neighborhood, our space is ideal for those who want to explore the city while enjoying a tranquil retreat.

Guest favourite
A cozy living area features a brown leather couch and a woven chair. A wooden coffee table is positioned at the center. Exposed wooden beams accentuate the stone wall backdrop, while a lamp provides soft lighting for the space.
Home
4.92 out of 5 average rating, 53 reviews

Lesvos Exclusive Lounge, Mytilene City Center

Lesvos Exclusive Lounge is a classically restored home located in the center of Mytilene. Located on the ground floor, the 60-square meter home includes one bedroom, one bath, a fully equipped kitchen and a 20-square meter private yard perfect for enjoying your morning coffee or a good book.

Popular amenities for house rentals in Mytilini

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