Guest house holiday rentals in Pima County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Pima County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Guest favourite
The exterior of a charming studio showcases a light-colored stucco facade. A dark wooden door with a decorative window is flanked by two large windows. Outdoor seating is provided by two rattan chairs and a small wooden table, complemented by desert landscaping.
Guest house in Tucson
4.92 out of 5 average rating, 180 reviews

🌵 Central Desert Oasis 2 🌵

Enjoy a stylish experience at this centrally located studio. 🚗 Free, private, secure parking 🧹 We do the cleaning - just lock up ☕️ All the caffeine you'll ever need 🚶🏼‍♀️Walking distance to 4th Ave (8mins) 🚶🏼Walking distance to University (6 mins) The Pie Allen neighborhood (our neighborhood) is ranked as the 3rd safest neighborhood in Tucson with a walk score of 85/100 and bike score of 99/100 on walkscore (a website that rates the walkability of neighborhoods). Can’t wait to see you!

Top guest favourite
Guest house in Tucson
4.97 out of 5 average rating, 442 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favourite
A vibrant purple door welcomes guests, featuring a small window at the top. A doormat with the phrase 'BE OUR GUEST' is positioned at the entrance, enhancing the inviting atmosphere of the porch.
Guest house in Tucson
4.98 out of 5 average rating, 209 reviews

Cute eco-built guesthouse

This guesthouse is constructed with well-insulated EF Block, has tinted clay plaster walls for a relaxed and earthy interior, and is powered by solar panels. Recently built, the space is small but functional, with a comfortable queen-sized bed, kitchenette, dining space, and modern bathroom. A covered patio includes a grill, outdoor seating area, and twinkle lights to enjoy cool evenings. Centrally located, you have easy access to dining, stores, the University, bikeways, and more.

Top guest favourite
A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.
Guest house in Tucson
4.98 out of 5 average rating, 487 reviews

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Top guest favourite
A spacious living area is characterized by wooden floors and natural light from large windows. A comfortable gray sofa is positioned next to a low coffee table, while a TV stand holds a flat-screen television. A dining table with chairs completes the space.
Guest house in Tucson
4.98 out of 5 average rating, 366 reviews

Cozy casita in historic midtown neighborhood

Cozy casita located in historic San Clemente neighborhood in the heart of midtown. Steps away from Randolph Park and Golf Course, Tucson Zoo, Hi Corbett Field and El Con Mall. Less than 3 miles separates you from the UofA campus and downtown Tucson. Nearly 600sqft, private entrance, dedicated off-street parking. Full kitchen, new fridge, 50" HDTV with every DIRECTV channel, queen size bed and full bathroom. Ample light via french doors and large oversized sliding windows.

Top guest favourite
The bright bedroom features a spacious bed with soft linens and two yellow accent pillows. Natural light fills the space through large windows, which overlook a serene outdoor area with cacti. Comfortable seating options, including armchairs and a round pouf, accompany the bed.
Guest house in Tucson
4.95 out of 5 average rating, 537 reviews

Central and Stylish Midcentury Pool House

Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

Top guest favourite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guest house in Tucson
4.96 out of 5 average rating, 885 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favourite
Two comfortable chairs in a light-filled studio create a cozy sitting area. A small table is placed between the chairs, and a view of the outdoor patio is seen through the glass doors. A vibrant area rug adds color to the wooden floor.
Guest house in Tucson
5 out of 5 average rating, 126 reviews

Cactus Bud Casita Inviting Bright Studio Near UofA

The Cactus Bud is a newly remodeled, light filled studio casita. The space is inviting and comfortable. It is well appointed with an incredibly comfy bed, extra pillows, room to practice yoga, read a book, make art, play cards, enjoy a meal, lounge and work. The outdoor patio has a shade sail, two chairs, a hammock and an expandable table. Take a stroll to enjoy the beautiful gardens and native plantings in our quiet and centrally located neighborhood.

Top guest favourite
A serene entryway is framed by a large, leafy tree, with a light green door visible in the center. A brick path leads to the entrance, surrounded by vibrant greenery, cacti, and decorative stones. A seating area is positioned to one side, enhancing the natural atmosphere.
Guest house in Tucson
4.99 out of 5 average rating, 255 reviews

Saguaro Oasis Retreat near National Park

If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Guest favourite
An inviting entryway features a blue dresser with floral accents and a small yellow dinosaur figurine. Two doors lead to a bathroom and kitchen, while open shelving displays decorative items. Light-colored walls and tile flooring enhance the bright atmosphere.
Guest house in Tucson
4.9 out of 5 average rating, 285 reviews

Renovated Casita with Private Courtyard

Escape to your private, sparkling clean casita in the heart of Tucson! This stylish, fully renovated retreat for two features a full kitchen, a cozy queen bed, and a private courtyard with a grill and string lights. Perfectly located just 1.3 miles from the University of Arizona and a 5-minute drive to downtown, it's an ideal base for exploring the city. Enjoy the peace of a quiet neighborhood with easy access to everything.

Guest favourite
A small bedroom features a single bed dressed in a blue and white patterned quilt. A simple wooden dresser is positioned beside the bed, and a woven placemat rests on the dresser's surface. A lamp provides soft lighting, with a wall shelf visible in the background.
Guest house in Tucson
4.77 out of 5 average rating, 105 reviews

Tiny House in Central Tucson

A great location in central Tucson in an artists sculpture garden. Private and quiet, in a friendly Enclave. Bathroom is shared, and 2 outdoor kitchens are shared. Patio dining areas available, completely furnished, Wifi, microwave, fridge, appliances, and close to coffee shop, restaurants, three major hospitals, and the University. Sorry, but it's not available for couples. Please introduce yourself - thanks much!

Top guest favourite
The vibrant blue exterior of the guesthouse is softly illuminated by warm lights, highlighting the welcoming entrance. A textured stone path leads to the door, flanked by a cozy seating area with two chairs and a small table, set amid the serene outdoor landscape.
Guest house in Tucson
4.98 out of 5 average rating, 638 reviews

TREAT GUEST HOUSE Private, Quiet, Comfortable

Welcome to a one-of-a-kind guesthouse created by a Swiss-born professional photographer and freelance artist. This attractive open studio space is part of my "Gesamtkunstwerk" (entire body of work), still in flux. Featuring murals and curated pieces from across a lifelong creative journey. Thoughtfully designed with passion and purpose, the space offers both inspiration and comfort in the heart of Tucson.

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