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Holiday rentals in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A vibrant red house is surrounded by lush greenery, showcasing diverse plants in large pots. The exterior features unique architectural details and large arched windows. A stone pathway guides the way to the entrance, offering a welcoming glimpse of the inviting atmosphere.
Cottage in Santo Domingo Ocotitlán
4.92 out of 5 average rating, 142 reviews

Tepoztlán in the mountains. Magical and peaceful!

The house is situated in a beautiful valley nestled in the Tepozteco mountain range. The location is peaceful, quiet and safe. Its architecture is reminiscent of North African desert houses, offers comfortable spaces with private areas suitable for two couples or one family. The living and dining rooms open onto the garden. All the necessary amenities for cooking and enjoying meals are provided. Whether you want to sleep, relax, meditate, walk, or read, this is the perfect place! good internet

Guest favourite
A spacious living area is framed by large windows that overlook a lush garden. A curved sectional sofa adorned with decorative cushions invites relaxation, while a round coffee table displays small art objects and fresh flowers. Light filters through, highlighting the vibrant wall colors.
Apartment in Roma Norte
4.96 out of 5 average rating, 163 reviews

Breathtaking duplex in the heart of the Roma

With an unbeatable location in the heart of the Roma Norte neighborhood, is steps away from great cafes, restaurants and galleries. Thoughtfully newly decorated by a recognized European interior designer based in Mexico, the apartment is full of magical touches -art. The dining area will make you live an unforgettable experience. In the terrace you can relax and dine al fresco in complete peace and privacy. Unique apartment! King bedroom on the second floor, loft-style with a semi-open layout.

Guest favourite
A sunlit corner features large floor-to-ceiling windows offering views of greenery outside. A dark wooden table is accompanied by two cushioned seats, while a cozy seating area with a collection of books and decorative items is situated nearby, contributing to a serene environment.
Flat in Condesa
4.88 out of 5 average rating, 129 reviews

Kaya Kalpa-Organic Designer Apartment in Condesa

After a year-long remodeling project, I’m thrilled to present this personal residence Kaya Kalpa. Every inch of the property has been thoughtfully remodeled. Ideal place for artists, wanderers, all walks of life practitioners to come reset, reflect, and create.  The space is located on Amsterdam street in Condesa, one block from Parque Mexico. You’ll find all nice restaurants, cafes, and stores downstairs. Big supermarket, local Mercado, metro station…all within 5 minutes walking distance.

Top guest favourite
The image captures a spacious terrace adorned with various potted plants, leading to a bright bedroom area. Large glass doors open to the patio, allowing natural light to fill the space. A serene landscape and a clear blue sky complement the vibrant greenery.
Loft in Santa María La Ribera
4.96 out of 5 average rating, 340 reviews

Sunny loft with a big terrace in a historic area

New and spacious two stories loft on an award winning renovated building from the 1940´s. Security 24/7 , personal digital code to access the apartment, wifi, fully equipped kitchen, Smart TV with Netflix/Mubi, and a shared laundry room in the building. The loft has one patio in the first floor and a huge terrace full of plants on the second floor next to the bedroom. It is usually very quite but there could be a little noise during the day if another apartment is doing renovations.

Top guest favourite
Loft in Roma Norte
5 out of 5 average rating, 14 reviews

Iconic Designer double-height loft · Roma Norte

KAAN KIN is a double-height loft with soaring ceilings, warm interiors and natural light. Thoughtfully designed with curated furniture, hotel-quality bedding, a fully equipped kitchen, 75” TV and Sonos system. Fast Wi-Fi for remote work. Steps from Roma Norte’s best restaurants, cafés and parks. Seamless self check-in, responsive host and a space prepared to hotel standards before every stay. A private residence with boutique hotel care — designed for guests who notice the details.

Guest favourite
Flat in Del Carmen
4.88 out of 5 average rating, 17 reviews

Heart of Coyoacán - Balcony & Workspace

Stay in the historic heart of Coyoacán, less than one block from the iconic main plaza. Walk to Frida Kahlo Museum (Casa Azul), Leon Trotsky Museum, Coyoacán Market (3 blocks), Artisan Market (2 blocks), cafés, restaurants, parks, and galleries. This light-filled, architecturally designed apartment features a private balcony and dedicated workspace with fast WiFi — perfect for digital nomads and longer stays in one of Mexico City’s most charming, walkable neighborhoods.

Guest favourite
A modern cabin is nestled among tall trees, showcasing large windows that invite natural light. A hammock hangs nearby, providing a relaxing spot. The surrounding terrain is covered with natural foliage, creating a tranquil outdoor setting.
Hut in Tepoztlán
4.95 out of 5 average rating, 190 reviews

Ivan's little cabin

Enjoy the outdoors in the forest. In the morning you can listen to the birdsong with a coffee, take the time to connect with your tribe and enjoy the day as few can. The cabin is located 15 minutes from the center of Tepoztlán by vehicle or 5 minutes walk to the transport that will take you to the center. You can also avoid all the traffic as you don't need to cross downtown. Very convenient for long weekends and holidays. The property is fenced. Vegetation varies.

Superhost
A modern open-concept living space is presented, featuring large glass doors that connect to a serene outdoor area. The kitchen, adorned with wooden accents, leads to a cozy seating area. Lush greenery surrounds a small plunge pool, enhancing the tranquil atmosphere.
Tiny home in Tepoztlán
4.92 out of 5 average rating, 236 reviews

Luxury loft with private jacuzzi in Tepoztlán

Welcome to Ixaya, a luxury loft designed to offer comfort, privacy and an atmosphere of deep relaxation in the middle of Tepoztlán's nature. Here you will find an ideal retreat to disconnect: king size bed, private heated Jacuzzi (extra cost), equipped kitchen, large windows and two exclusive gardens that fill each space with light and serenity. Located in a quiet and safe residential development, just 12 minutes from downtown, you can enjoy its unique energy.

Superhost
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Coyoacán
4.88 out of 5 average rating, 221 reviews

Casa Mavi's loft in Coyoacán

Welcome to Coyoacán! Great 120 m2 loft located just a 5-minute walk from downtown Coyoacán. Experience this quiet and bright open space, ideal for resting or working and decorated with objects full of stories. The loft is located on the third floor of Casa Mavi, an old factory that was remodeled to create a place full of charm that makes it unique. It has shared terraces. With option for a third guest. 200 megabyte Wi-Fi.

Guest favourite
Villa in Tepoztlán
4.97 out of 5 average rating, 174 reviews

Casa Aluna - Oasis in the Mountain, Premium Villa

Casa Aluna is built in the heart of the mountain on a big compound with 2 independent villas. It is a place to enjoy the surrounding nature and disconnect from the city. Amazing views of the sunset and Tepoztlan mountains. You can enjoy nature walks nearby and visit local restaurants for a culinary experience, we are located 15 minutes from downtown Tepoztlan and Mexico City (80 minutes).

Superhost
Flat in Tláhuac
4.83 out of 5 average rating, 53 reviews

Remodeled apartment, kitchen and garden.

10 Blocks from Metro Line 12 Tlahuac Terminal, Independent apartment with kitchen service, full bathroom, small rest room, dining room with refrigerator, microwave and double bed and a parking space. You can use a nice wood and charcoal grill plus gas grill in the large garden, or just spend the afternoon in the courtyard surrounded by vegetation.

Superhost
A spacious living area showcases natural light streaming through expansive glass doors, revealing a stunning mountain view at sunset. Comfortable seating options are arranged to enhance relaxation, while an outdoor terrace is visible, blending the interior with the scenic landscape.
Cottage in Santo Domingo Ocotitlán
4.86 out of 5 average rating, 390 reviews

Tepoztlán Mountain House with the best mountain view

Enjoy the scenery, nature, and unplug from civilization. The house is well integrated into the landscape, built with local stone. We offer everything you need to enjoy a very relaxing stay. The view is spectacular and the sunset unforgettable. Ideally designed for two people but can accommodate a maximum of four people.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz