
Places to stay near Six Mile Cypress Slough Preserve
Book unique holiday rentals, homes and more on Airbnb
Top-rated holiday rentals near Six Mile Cypress Slough Preserve
Guests agree: these stays are highly rated for location, cleanliness and more.

Private farmhouse stay at Dim Jandy Ranch.
Take it easy at this unique and tranquil getaway. A beautifully appointed bed and bath in a separate building from the house. We have goats, donkeys and chickens and a Highland cow, all super friendly. Sit and relax on your private, beautiful lanai or any of our farm tables placed around the property. Join us as we feed the animals. Or even join in one of our Goat Yoga classes! We're easily located close to I-75, airports, shopping, beaches, downtown. Perfect for couples or solo travelers.
4.99 out of 5 average rating, 255 reviews
LUX Villa w/ Private Salt Water Pool, Lanai, Canal
Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!
4.99 out of 5 average rating, 264 reviews
Central 3BD/2BA •Massive Heated Pool •Golf courses
🌞 Gorgeous Heated Pool Home Near Everything – Perfect for a Relaxing & Convenient Getaway! Welcome to your tropical escape in the heart of SW Florida! This beautifully maintained 3BD/2BA home is located just minutes from world-class beaches, and top local attractions, offering the perfect blend of tranquility, comfort, and accessibility. Whether you're here for a family vacation, a romantic getaway, or a business trip, this home provides everything you need for a restful and memorable stay.
4.96 out of 5 average rating, 237 reviews
Paradise on Estero Bay
Welcome to Mullock Creek a Boater's dream! Southwest views boasting breathtaking sunsets overlooking gulf access canal from your spacious backyard, just minutes away from shopping and dining at Coconut Point, and Gulf Coast Town Center. This stunning Key West Style home has been beautifully maintained and updated offering a lovely front entrance, fully equipped kitchen, spacious Living Room, dining room, Wi-Fi, private driveway with access to the open garage, fully furnished and private pool.
4.94 out of 5 average rating, 163 reviews
Inn Season Cottage-Cozy Florida Living
Welcome to the Inn Season Cottage...where relaxation, family time, and sunshine are always "INN" season. Experience cozy Florida living in this newly renovated 1250 sq. ft. home located in the desirable McGregor Corridor. This home is nestled within a quiet neighborhood and provides a relaxing setting for your family to unwind and make memories together. It is the ideal location for seasonal visitors looking to stay during the winter months, a small family vacation, or a couples getaway.
5.0 out of 5 average rating, 102 reviews
Escape to the "Oasis"!
DISCOUNTS: Weeks...1=10%, 2=15%, 3=20%, 4=25%. Welcome to the "Oasis"! Escape to the water and stay on a canal in beautiful Cape Coral! Enjoy this 3 bedroom, 2 bath home. Swim in the pool, sit on the patio, fish from the dock, sit at the tiki bar for a drink, or take a nap on the lanai to get away from it all! There is a 50 foot long dock with 30 and 50 amps, so bring your boat! The Gulf is accessible by boat and Ft Myers Beach & Sanibel/Captive Island activities and beaches nearby!!
4.99 out of 5 average rating, 191 reviews
Luxury Riverfront Retreat • Pool & Spa • 60ft Dock
Luxurious 4BR 3.5Bath villa located in a prime location, directly on the Calosahachee River in a sought-after waterfront area near downtown. Magnificent expansive backyard with high-end amenities and direct river access ✔ 4 bedrooms ✔ Open Design Living ✔ Full Kitchen ✔ Patio (Pool and Hot tub, Bar, Dining, BBQ) ✔ Expansive Tropical Yard ✔ Indoor/Outdoor Surround Sound ✔ 7 Smart TVs ✔ High-Speed Wi-Fi ✔ Large Private pier/dock w/ boat & jet ski lift and a Tiki Hut! See more below!
5.0 out of 5 average rating, 104 reviews
Blue Beach Bungalow....
3 large bedrooms (3 king sized beds) with TV in everyroom, plus a full den, laundry room, HEATED pool and the house has its own beach with an in-ground fire pit that seats 12, lounge chairs, and sunset views! Walking distance to shopping centers, great restaurants, 20 minutes to RSW Airport and Fort Myers' white-sand beaches, perfect for a romantic get-away and 10 minutes from downtown Fort Myers Completely remodeled in July of 2021 with brand new appliances electronics,
4.83 out of 5 average rating, 205 reviews
Modern City Loft in Downtown River District
Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.
4.99 out of 5 average rating, 104 reviews
Whole cozy house
Entire cozy house just for you friends and family. Perfect to spend a pleasant and relaxed moment. If you plan to have a party or event, this place is NOT for you. The neighbors are very strict in terms of noise and large groups of people. Well maintained house. CLEAN POOL BUT NOT HEATED. Walk in to a living area and separated dining. 20 minutes to airport, 25 minutes to the beach, fine dining and entertainment. For a virtual tour, click on the cover photo twice.
4.95 out of 5 average rating, 405 reviews
Dolphin beach house 2
ONE OF THE BEST WATERFRONTS IN CAPE CORAL! A short walk to the beach . This 2,500+sq ft home has stunning sunsets and South Western water views from all main living areas,as well as the Master Suite. Heated pool w/ LED colored lighting, built in Spa,Pool bath, full laundry facility, Lanai,Fireplace ,Wi-fi and TVs in every bedroom, private dock . Boat on lift for rent w/RPM rentals . Large 2-car garage w/5 bicycles,beach wagon & cooler on site.
4.97 out of 5 average rating, 326 reviews
“Dream Vacation”Pool.Near airport&baseball
A few short miles from RSW International Airport, beaches, Twins/ Miracle's baseball, and downtown Ft. Meyers (McGregor). Walking distance to FSW Sunpark stadium. Safe and quiet neighborhood. Private pool *NOT HEATED*. Lanai TV has streaming service so you can log into your account. Click on our picture to view our five homes in Cape Coral/Ft. Myers/Delray Beach. All beautiful & with exceptional Super-host service and care.
4.98 out of 5 average rating, 245 reviewsPopular amenities for holiday rentals near Six Mile Cypress Slough Preserve
Other top sights near Six Mile Cypress Slough Preserve
Apartment rentals with wifi

Sunny Florida condo!
4.76 out of 5 average rating, 111 reviews
100+ 5 Star Reviews and Right on The Beach!
4.95 out of 5 average rating, 121 reviews
Beachfront fully equipped apartment
4.91 out of 5 average rating, 128 reviews
Lovers Key Resort/Ft Myers Beach/Condo/Pool/View
4.94 out of 5 average rating, 191 reviews
Rare walkout condo on Sanibel beach
4.9 out of 5 average rating, 263 reviews
Lovely Gulf Access/Kayak, Beach, Tiki Bar & Grill.
4.86 out of 5 average rating, 210 reviews
View of Gulf, Steps to Beach@The Turquoise Turtle
5.0 out of 5 average rating, 103 reviews
Ft Myers Beach & Lovers Key State Park- FANTASTIC!
4.93 out of 5 average rating, 214 reviewsFamily-friendly house rentals

Unforgettable Pyramid home in sunny Florida 7046
4.89 out of 5 average rating, 273 reviews
Perfect Getaway with Heated Pool - Pets Welcome
5.0 out of 5 average rating, 56 reviews
Mini Golf • Heated Pool • Near Beach Prime
4.96 out of 5 average rating, 25 reviews
Live the Comfort at exclusive Pratt Preserve home
5.0 out of 5 average rating, 4 reviews
Trendy 3b/2b prestige location home with a pool!
4.99 out of 5 average rating, 89 reviews
Luxury Riverfront Estate & Pool
4.67 out of 5 average rating, 3 reviews
Family-Friendly 3BR | Near Baseball, Beaches & RSW
4.95 out of 5 average rating, 20 reviews
Family Oasis with Heated Pool, Hot tub and Games
4.8 out of 5 average rating, 56 reviewsApartment rentals with air conditioning

Prime Location w/ Private Patio + Outdoor Kitchen
4.9 out of 5 average rating, 154 reviews
Villa San Carlos Park
4.94 out of 5 average rating, 157 reviews
Twin Palm - Sunny Days & Breezy Nights
4.96 out of 5 average rating, 110 reviews
Vacation in Paradise
4.99 out of 5 average rating, 157 reviews
Downtown Studio: Full Kitchen, King Bed, & Pool 6
4.85 out of 5 average rating, 183 reviews
Resort Style Pool Adj Beds-Wilder Sunset Views!
4.93 out of 5 average rating, 134 reviews
Blackstone Villa
4.95 out of 5 average rating, 160 reviews
The Pearl | River Views | King | Pool+HotTub+Gym
5.0 out of 5 average rating, 11 reviewsOther great holiday rentals near Six Mile Cypress Slough Preserve

Cozy haven
5.0 out of 5 average rating, 6 reviews
Waterfront Oasis w/ Heated Pool, Spa & Boat Dock
5.0 out of 5 average rating, 42 reviews
Luxury Riverfront:Pool, Tiki Bar & Outdoor Kitchen
5.0 out of 5 average rating, 96 reviews
3 bed/2 bath Saltwater Pool House Near Everything
5.0 out of 5 average rating, 24 reviews
Elite Living | Kayak | Joy Pool | Outdoor Kitchen!
4.94 out of 5 average rating, 16 reviews
TikiTime Tropical Riverfront Retreat
4.84 out of 5 average rating, 25 reviews
Pool, Putting Green, Sunroom | Beachy Bungalow
5.0 out of 5 average rating, 13 reviews
Waterfront Pool Home/Sailboat Access & Dock
4.87 out of 5 average rating, 89 reviewsDestinations to explore
- Naples Beach
- Captiva Island
- Manasota Key Beach
- Englewood Beach
- Lovers Key Beach
- Florida Gulf Coast University
- Tigertail Beach
- Bowman's Beach
- Stump Pass Beach State Park
- Blind Pass Beach
- Montura Ranch Estates
- Jetblue Park
- Barefoot beach Bonita Springs,FL
- Bonita National Golf & Country Club
- The Naples Pier
- Boca Grande Pass
- Edison & Ford Winter Estates
- Yacht Club Public Beach
- Ave Maria University
- Coconut Point
- Clam Pass Park
- Bunche Beach
- Delnor-Wiggins Pass State Park
- Barefoot Beach State Preserve





