House holiday rentals in Tower Grove South

4.9 out of 5 average rating, 431 reviews

Home in Bevo Mill

Sunny South City Guest House

Newly-rehabbed & cozy guest house. Everything you need is located here in the historic Bevo Mill neighborhood. In the heart of south St. Louis city, you’re steps away from local businesses, including the picturesque, historical Das Bevo. Step into a vintage-styled oasis, featuring large windows with plenty of natural light, tall vaulted ceilings, comfy queen bed, unique fridge, breakfast bar, sizable bathroom with a large walk-in shower. Hang outside at the picnic table under cute string lights.

4.99 out of 5 average rating, 133 reviews

Home in Dogtown

Near Forest Park, The Hill, WashU-Private Backyard

Backyard is private, large, fully fenced. Sitting area w/ solo stove & Adirondack chairs. Cleaned & maintained by host. Inside 1 bedroom you will find comfy king bed, queen sofa in living room. Modern amenities, fully stocked kitchen, & coffee bar. First floor laundry. Centrally-located, newly updated near The Hill & Forest Park. 1 min. from highway & no more than 10 mins from most everything STL-restaurants, downtown, hospitals, zoo, science center, coffee shops, stadiums & more! Dogs allowed!

Home in Shaw Historic District

4.92 out of 5 average rating, 130 reviews

Magnolia House | Parkside Shaw | Botanical Garden

Welcome to Magnolia House, a modern, renovated 1st floor flat in the historic Shaw Garden District. Designed for short and long-term stays, the spacious living room, fully equipped kitchen, dedicated workspace, backyard w/grill and picnic table, and two king-size hotel-quality bedrooms make it the perfect home away from home. Conveniently located on Tower Grove Park and the Botanical Gardens w/easy access to highways, hospitals, and STL's best neighborhoods. Message for discounted 30+ day stays!

4.99 out of 5 average rating, 113 reviews

Kalisto House: 420 Retreat w/Concierge & Hottub

Take it easy at this tranquil retreat in historic Tower Grove Heights, St. Louis. Nestled in a preserved 120-year-old flat, Kalisto House offers an immersive experience for the canna-curious to the Cannaseur. With cannabis-inspired art, a serene meditation room, and concierge service, this sanctuary invites you to explore, unwind, and connect. From personalized pairings to guided rituals, every detail is curated for an unforgettable, elevated escape. Ask about premium & bespoke experiences.

4.97 out of 5 average rating, 124 reviews

Home in The Hill

The Chocolate Suite - Walkable and Peaceful

The last true "Little Italy" in the U.S. Whether you are looking for a peaceful and convenient place to work or a romantic and cozy place to relax and connect, our suite is designed to meet your needs. Pool table, outdoor patio, back yard, premium bed, comfortable desk, high-speed internet, complimentary chocolates to name a few. Italian restaurants, cafes, shops, and markets within walking distance. Free off-street parking, easy highway access, and close to everything. Safe and friendly.

4.96 out of 5 average rating, 144 reviews

Granny's DOG House - KING BED - One of a Kind!

ONE OF A KIND HOUSE - Welcome to Granny's Dog House! This cozy 2BR/1BA retreat, designed for dog lovers, offers a king bed in BR1, two twin beds in BR2, and charming dog-themed décor. Enjoy our fully-equipped kitchen, pristine bathroom, & fenced backyard for your furry friends. Unwind in a lovingly curated home, surrounded by dog photos, sculptures, and the warmth of canine camaraderie. Experience love, laughter, and wagging tails at our house for you and your four-legged family members!

4.99 out of 5 average rating, 202 reviews

Home in North Hampton

Sparkling Vintage Charmer, King Bed, Quiet Comfort

The Fairview is a vintage modern 2BR home in desirable North Hampton (south StL city). We've taken special care to offer a unique, memorable experience while providing the convenient, clean comfort you expect in an overnight stay. You'll have easy access to two major highways which means most StL attractions will be minutes away. (The drive to Barnes Hospital is less than 10 min.) The Fairview is nearby restaurants, coffee shops and shopping––it's the perfect place to live like a local!

4.96 out of 5 average rating, 116 reviews

The Urban Refuge | 3BR | Fireplace+Backyard+W/D

Welcome to the Urban Refuge, a stunning 3BR house in an unbeatable Saint Louis location. Nestled between the picturesque Tower Grove Park and the vibrant South Grand district, this home offers the perfect blend of tranquility and excitement. Explore the park, sample one of the many international dining options on South Grand, and unwind with a cozy nightcap by the fireplace. After a restful night's sleep, start your day right with a morning coffee in the peaceful backyard.

4.97 out of 5 average rating, 642 reviews

Home in Tilles Park

Garden Cottage-Safe Private Parking!

Mindfully renovated cozy bungalow offering a lush vibrant landscaped garden, meandering brick patio & deck overlooking waterfall pond w/ Koi fish. We lovingly restored our efficient space with a mix of old & new furnishings and updated appliances. A Romantic luxurious vibe ❤️ The perfect nest for two! Our quiet safe neighborhood is home to fabulous restaurants, bars, coffee shops and galleries. Close to everything including Hwys 40, 44, 55 . PLUS safe private parking

4.94 out of 5 average rating, 666 reviews

Home in Tower Grove East

Little Red House, Entire House in Tower Grove East

This 2 Bedroom 1 Bath home is centrally located in Tower Grove East, 5 minutes from St. Louis University, 8 minutes from Grand Center and just a few short blocks from hip South Grand and Tower Grove Park. It is the entire house all to yourself. The block is quiet and the neighbors are friendly but please note this house is located in an urban area. While generally safe it is racially and economically mixed. Please set your expectations accordingly.

4.97 out of 5 average rating, 159 reviews

The Gateway Getaway Families | Near Park & Dining

Perfect for families or groups, this spacious 4-bedroom, 3.5-bath St. Louis home offers 6 comfy beds, 2 workspaces, and a chef’s kitchen. Kids can play in the fenced backyard while adults relax or cook together. Walk to Tower Grove Park, then explore South Grand’s amazing restaurants, bars, and shops just blocks away. Enjoy comfort, convenience, and local charm — all in one stylish home base for your St. Louis stay.