
Places to stay near Buffalo Museum of Science
Book unique holiday rentals, homes and more on Airbnb
Top-rated holiday rentals near Buffalo Museum of Science
Guests agree: these stays are highly rated for location, cleanliness and more.

D&C Airbnb adds home-like comfort to your travels.
D&C Airbnb adds home-like comfort to your travel experience. Clean, cozy, quiet and secured 2nd floor apt. Centrally located on Main Street near main highway and public transportation. Your stay includes living room with flat screen tv and surround system and dining room seats four.Living and dining room areas have original woodwork. All standard kitchen amenities including microwave and coffee maker. Bathroom has full size tub and shower. Two bedrooms with queen size beds & ample closet space.

The 2D Spot!
Buffalo's 1st official 2D Airbnb; all hand painted by local Artists. With ideal proximity to DT Buffalo, Elmwood Village & Allentown, you'll find yourself at the heart of the city's culture. Also just a 25 minute drive to the iconic Niagara Falls. Whether you're a first time visitor to Buffalo or a local seeking a unique escape, The2DSpot invites you to step inside the pages of a comic book. Immerse yourself in a world of imagination & book your stay today! Experience Buffalo like never before.

Historic Apartment Steps Away from Allentown Area
This spacious 1-bedroom apartment is conveniently located in the heart of Allentown. It is fully furnished and includes everything you will need to have a comfortable, enjoyable stay. This is 1 of 3 airbnbs located in a historic multi-unit home. This space is the perfect getaway for couples, business stays, and traveling nurses. It is situated in a quiet residential neighborhood, steps away from Allen St. The front door opens to a small park that was designed by Frederick Law Olmsted in 1887.

Elegant Elmwood Village Hideaway-New Outdoor Patio
New in July 2025 - Outdoor Patio! Bright, spacious 3 bedroom apartment at the gateway to the Elmwood Village; over 300 local shops, coffeehouses, restaurants, bars, and art galleries. The house is set back from street with off street parking. Private grand entrance to a large living/dining room, gas fireplace, hardwood flooring throughout. Walk to: Albright Knox Art Gallery, Burchfield Penney Art Center, Buffalo State, Delaware Park, Hotel Henry and more. Niagara Falls only 20 minutes away.

Modern Full Home: Hot Tub, Updated Kitchen & Bath
**This is an entire home listing. There is no one else that will be at the house.** Enjoy a stylish experience at this centrally-located single family home. With an updated kitchen, a/c downstairs master BR, guest BR and attic (may-sept). Ultra modern bathroom has a walk-in shower with 2 rain shower heads, 1 extra deep bathtub, heated floor, marble counter tops & bidet Outside you will have a large back porch which includes a hot tub & string lights to enjoy during the cool Buffalo evening.

Hidden Parkside Carriage House near everything.
This beautifully redone 1915 Carriage house that is just 2 blocks from Delaware park , The zoo and the Darwin Martin house. Fully updated with plenty of room to cook and relax. 55in Smart tv and all brand new furniture. If you do not want to drive it is a 2 block walk to the train that can take you right downtown, Canalside or the Keybank Center (Sabres Arena) . Located right off the 33 so minutes to the airport , downtown and about 20 minutes to Niagara Falls and 20 to Highmark Stadium.

Luxury Rooftop Loft Gym Pickleball+ Basketball EV+
Welcome to our enchanting loft, where romance meets family-friendly charm in a historic setting. This unique space has been the backdrop for 3 movies. Tesla EV charger. Enjoy light therapy experienced through stained glass, a gym with Peloton and rowing machines. Challenge friends on the indoor basketball court. Enjoy seasonal rooftop with a grill and lounge chairs for delightful gatherings. Enjoy tree-lined stroll to vibrant Elmwood Village & Allentown, with dining and shopping options.

Bright, Beautiful Lakefront @ Historical Fort Erie
Come home to relax in our beautifully decorated lakefront escape in the sweet town of Fort Erie. Our home is a large open concept with a smart TV, free Wi-Fi, fully equipped kitchen, 3 clean & comfortable bedrooms, 2.5 bathrooms and everything else you need for your perfect vacation. You'll be located across the street from the lake and a 2 minute walk to the old fort. Enjoy a stroll (or bike) along the lakeside path into old Fort Erie where you will find shops and fine restaurants or pubs.

Niagara Riverview Entire Cottage, EV Charger
The Light House Cottage offers a peaceful retreat with a stunning view of the Niagara River. Equipped with a Level 2 EV Charger,. Just 15 minutes drive from the breathtaking Falls and only 5 minutes drive from the nearest business district. It provides both scenic beauty and convenient access to everything you need. Enjoy a charming walking trail right outside the house along the river, creating the perfect escape from city life to spend precious time with loved ones in a tranquil setting.

Clean, Spacious, Convenient, Comfortable, Historic
- Impeccably decorated - Recently updated - 1st-floor apartment of a - Historic home - Heart of Buffalo - A few minutes to all of Buffalo's favorite spots - Budget conscious Midtown is a distinctly urban and multi-cultural neighborhood that is beginning a renaissance. If you are intimidated by the urban setting, you might be out of your comfort zone. You will see a few vacant houses and might hear a distant ambulance (nearby hospital) in this safe and quiet neighborhood.

Cozy Apartment in LarkinVille (Unit 2)
If this listing is not available please check out my other listings This 1st floor apartment features an open concept kitchen & living room with stove, refrigerator & microwave. A queen sleeper sofa & 54" smart TV are in the living room. The bedroom has a queen bed & dresser. The space features a In unit washer & dryer soaker jacuzzi tub and A/C mini split to help cool down the space. This is a mix use property with periment tenants as well as other guest. Noise is typically low

Five Points Apartment- Upper Unit
Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls
Popular amenities for holiday rentals near Buffalo Museum of Science
Apartment rentals with wifi

Elmwood 1 King 1 Queen 1.5 bath Garage EV Charger

Lovely Niagara Falls Vacation Home

The Eugene

1 Bedroom Luxury Bi-Level Condo at 500 Pearl

Entire Condo Minutes from Niagara Falls (USA)

Quiet nice and clean apartment downtown Buffalo

Historic apartment overlooking FLW Martin House

Chic Contemporary 2 Bedroom Minutes from the Falls
Family-friendly house rentals

Modern Kenmore Getaway | Renovated Home in Buffalo

Downtown Home W HOT TUB Private Deck & HiddenRoom

Treasure Tree

The Italianate: Luxury Historic Home

Luxury Village Farmhouse

Timber-frame home on 12 wooded acres

Cozy Home for Relaxing Getaways

~ Fun, Vibrant, Village Home ~ Central to Buffalo
Apartment rentals with air conditioning

Cozy & Spacious Getaway! Centrally located.

Inviting King & Queen Flat •Parking •Laundry •Pets

The Parisian Master Room

Modern Studio in Allentown

Space, comfort and hospitality!

Charming Upper in Lively Entertainment District

Cozy 2 Bedroom Apt Close 2 Everything

Cozy S. Buffalo Retreat - 10 mins to Bills Stadium
Other great holiday rentals near Buffalo Museum of Science

Historic Mansion Built in 1896, Pan Am. Expo Era

Spa Stay | Hot Tub | Minutes to Niagara Falls

The Carriage House

Five Points Hideaway

Sleep Under The Stars

2bdrm single family home. Medical area

MODERN SPACIOUS 2-BR BEST LOCATION IN ALLENTOWN

Cheerful 5 bedroom home with big, bright kitchen.
Destinations to explore
- Letchworth State Park
- Holiday Valley Ski Resort
- Six Flags Darien Lake
- Niagara Falls State Park
- Buffalo RiverWorks
- Casino Niagara
- Niagara Falls
- Fallsview Indoor Waterpark
- Keybank Center
- Jackson-Triggs Niagara Estate
- Brock University
- University at Buffalo North Campus
- Vineland Estates Winery
- Seneca Niagara Resort & Casino
- 13th Street Winery
- Buffalo Convention Center
- Kissing Bridge
- Wayne Gretzky Estates
- Balls Falls Conservation Area
- MarineLand
- Highmark Stadium
- Lakeside Park Carousel
- Canisius University
- Butterfly Conservatory




