Holiday rentals in Byron

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Top-rated holiday rentals in Byron

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Guest favourite
The cozy living area features two inviting sofas and a wooden coffee table, surrounded by warm wood paneling. A flat-screen TV is mounted above a stone fireplace. Natural light floods in through expansive windows leading to the sunroom, where comfortable seating offers views of the lake.
Cabin in Lake City
4.92 out of 5 average rating, 105 reviews

Perched Above Pepin-cozy cabin,panoramic lake view

Charming cabin perched on a hill w/ stunning views of Lake Pepin.Enjoy a cozy atmosphere w/ a fireplace, modern amenities, & sunroom w/ breathtaking lake vistas. Watch eagles soar and barges pass by, while listening to the sound of trains rolling by along the river.Located near hiking trails, water activities, local wineries, and breweries, this cabin is perfect for outdoor adventures.With easy access to both Lake City and Wabasha, it’s an ideal getaway, blending comfort, nature, and attractions

Top guest favourite
A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.
Flat in Rochester
4.94 out of 5 average rating, 222 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Top guest favourite
A cozy seating area features a gray sofa and two armchairs with decorative cushions. A round coffee table sits in the center, accompanied by a plush area rug. A large TV displays a calming nature scene, while soft natural light filters through sheer curtains.
Home in Rochester
4.93 out of 5 average rating, 282 reviews

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families & professionals for the home away from home feel. Luxury Sheets and Posturepedic . Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, shopping etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home. No pets due to Mayo Clinic guests’ allergies.

Guest favourite
A single-story home is shown, featuring a red front door and a well-maintained exterior. Vibrant autumn trees with golden leaves line the walkway, and a grassy area is depicted in front of the house, inviting a sense of tranquility to the setting.
Home in Rochester
4.87 out of 5 average rating, 403 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

Top guest favourite
A welcoming book titled 'Welcome to Oasis' is displayed prominently, featuring a lotus flower design and neatly placed beside a decorative white vase. Greenery is visible in the background, adding a touch of nature to the inviting setting.
Home in Rochester
4.95 out of 5 average rating, 128 reviews

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Top guest favourite
A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.
Flat in Rochester
4.97 out of 5 average rating, 265 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Top guest favourite
The exterior of the home features a welcoming entrance with a porch, adorned with an American flag. The driveway leads to an attached garage, and landscaped green areas surround the entrance, creating an inviting approach.
Home in Rochester
5 out of 5 average rating, 155 reviews

Convenient, comfortable rambler near Mayo Clinic

• 1 mile to Saint Marys hospital and Mayo Clinic (Gonda) • Main level living — one 1 step up to front door • King bed, queen bed and daybed • Attached garage — huge perk in Minnesnowta! • Smart TVs w sectionals on main floor & basement, smart TV mounted in primary bedroom and a Roku TV in the queen size bedroom. • Two work spaces • Walk-in shower with grab bar • Serene rear patio with gas grill • Quiet neighborhood near Soldiers Field park, Apache Mall and biking/walking trails

Top guest favourite
The living area is highlighted by a modern gray sofa, accentuated with textured cushions. A sleek coffee table holds a glass vase with greenery, while art pieces adorn the wall. Natural light filters through sheer curtains, creating a bright and inviting space.
Home in Kutzky
4.96 out of 5 average rating, 140 reviews

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

Top guest favourite
Home in Rochester
4.96 out of 5 average rating, 170 reviews

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

Guest favourite
A modern kitchen is displayed, featuring white cabinetry contrasted against a deep blue wall. A stainless steel oven and a retro-style microwave are present on the countertop, alongside a coffee maker and kitchen utensils. Natural light enters through the window above the sink.
Home in Rochester
4.83 out of 5 average rating, 565 reviews

Cozy home next to Mayo Clinic & historic parks!

Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !

Top guest favourite
The exterior features a two-story structure with a wooden facade and large garage doors. A set of stairs leads up to the entrance, surrounded by natural stone landscaping and colorful flowers. Trees and greenery provide a serene atmosphere.
Apartment in Rochester
4.98 out of 5 average rating, 192 reviews

Cedar Loft is a tranquil retreat

If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.

Top guest favourite
An open living area showcases a dining table with a glass vase holding flowers. A cozy seating section with a brown couch and decorative pillows is visible nearby. Natural light enters through a large window, complemented by soft, neutral-toned walls and soft lighting fixtures.
Home in Rochester
4.96 out of 5 average rating, 170 reviews

You’re home! St.Augustine MAYO CLINIC garage!

Time to relax! 2 car Garage Parking (a Minnesota must!) Fast WiFi, smart tv! Washer and Dryer and dishwasher! Clean comfortable home in a great SAFE neighborhood convenient to everything. Recliner! Costco, the best grocery’s stores, bars, restaurants, and movie theaters 1 min away. Minutes from the Mayo Clinic! Quick and easy drive! Check out my other listings to see the 5 Star reviews!

Popular amenities for Byron holiday rentals

  1. Airbnb
  2. United States
  3. Minnesota
  4. Olmsted County
  5. Byron