
Holiday rentals in Cape Girardeau
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Cape Girardeau
Guests agree: these stays are highly rated for location, cleanliness and more.
0 of 0 items showing
1 of 3 pages
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Cape Girardeau holiday rentals
Other great holiday rentals in Cape Girardeau
Top guest favourite

Cabin in Jackson
4.94 out of 5 average rating, 33 reviewsThe Cabin at Timber Creek
JakeRating, 5 stars4 days ago
booked our second stay here again. Such a cool place. If we end up coming back, we will be staying here again.
Guest favourite

Home in Cape Girardeau
4.85 out of 5 average rating, 120 reviews5 Bed Home in Great Neighborhood - Sleeps 10
JeffRating, 5 stars1 week ago
Worked out perfect for our needs. Carla was very attentive. The home was as described.
Guest favourite

Place to stay in Murphysboro
4.93 out of 5 average rating, 46 reviews4Bdrm~EACHw/PRIVATEBathrms!
Shetara LatriceRating, 5 stars4 months ago
I hosted a slumber party for my 10 year old and 9 of her friends, THEY HAD AN ABSOLUTE BALL!! The second night, my husband, mother and 3 children enjoyed a night ourselves, and no one wanted to leave the next morning! Thank you for providing such a comforting atmosphere for my family and I to enjoy!
Top guest favourite

Home in Cobden
5 out of 5 average rating, 43 reviewsSouth Pass Hideaway
KellyRating, 5 starstoday
10/10!! This home is perfection! We enjoyed our girls’ weekend so much, and this home was the cherry on top! Beautiful inside and out! Exactly as described! House manual we received, in advance, gave us multiple options for local restaurants and things to do! The owners are extremely helpful and great at communication!! The kitchen was wonderful to cook in! We utilized the back deck, which looks out to the timber behind the home! Gorgeous!! We can’t wait to come back!!
Top guest favourite

Cabin in Makanda
4.98 out of 5 average rating, 118 reviewsHygge Log Cabin: HotTub & Hiking
AimeeRating, 5 stars1 week ago
We love hiking so we visited the Garden of the Gods, the Little Grand Canyon and the Giant City Nature Trail. This cabin is in a great location for visiting the Shawnee National Forest and perfect place to unwind after a day of hiking. The grill for making dinner was so clean, as well as the hot tub for relaxing. Also a fire pit out back. The kitchen had everything you could need. Shampoo and conditioner were also provided. This is by far the best Airbnb I have visited, HIGHLY RECOMMEND!!! We had a great time :)
Guest favourite

Cabin in Dongola
4.95 out of 5 average rating, 38 reviewsHotTub! FirePit, Private Pond, GameRoom! Slps12+
MaryRating, 5 stars6 days ago
Our group of long time friends had a great time there. The house is great and had lots of amenities. Very roomy and had one of the best stocked kitchens I’ve seen for a rental. We enjoyed the game room, fire pit and large deck. We would definitely rent there again! The host is quick to respond to any questions we had.
Top guest favourite

Cabin in Carbondale
5 out of 5 average rating, 23 reviewsCabin on hobby farm.
JenniferRating, 5 stars2 weeks ago
My son and I very much enjoyed our stay. Both Jill and Danny were very responsive to any of our questions, and we really loved the trail that we were able to access for our private use. The animals were so much fun to be around.
Top guest favourite

Cottage in Burfordville
5 out of 5 average rating, 58 reviewsEntire Cottage Nestled in the Woods
KarenRating, 5 stars4 months ago
My family and I have stayed at Lara's place the last few years, and we absolutely love it! There is no clutter but plenty of seating and lots of space to stretch and move about. The location is private and perfectly close to our family in Jackson. Everything is always clean and inviting. Perfect home away from home!
Quick stats about holiday rentals in Cape Girardeau
Total rentals
150 properties
Nightly prices starting at
£15 before taxes and fees
Total number of reviews
9.1K reviews
Family-friendly rentals
70 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with dedicated workspaces
80 properties have a dedicated workspace
Destinations to explore
- St. Louis Holiday rentals
- Paducah Holiday rentals
- Shawnee National Forest Holiday rentals
- Carbondale Holiday rentals
- Murray Holiday rentals
- Ste. Genevieve Holiday rentals
- Meramec River Holiday rentals
- Belleville Holiday rentals
- Paris Holiday rentals
- Lake of Egypt Holiday rentals
- Marion Holiday rentals
- Nashville Holiday rentals
- Rentals with a patio Cape Girardeau
- Pet-friendly rentals Cape Girardeau
- Flat rentals Cape Girardeau
- Family-friendly rentals Cape Girardeau
- House rentals Cape Girardeau
- Rentals with a firepit Cape Girardeau
- Rentals with a fireplace Cape Girardeau
- Rentals with a washing machine and dryer Cape Girardeau
- Cabin rentals Cape Girardeau
- Rentals with outdoor seating Cape Girardeau
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom