
Family-friendly rentals near Case Western Reserve University
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals near Case Western Reserve University
Guests agree: these stays are highly rated for location, cleanliness and more.

Gem in the heart of Little Italy! 3BR-DN
12/5 - 1/1/27 GUESTS MAY PARK IN DRIVEWAY! Enjoy your stay at this centrally located - lower unit- in a two-family home in Little Italy. Complete with a well-equipped kitchen. The living room includes comfortable seating for 6, smart TV, 3 poufs & coffee table - so ALL may rest their feet from a long day, modern furnishings & laundry room. Each bedroom includes USB plugs in the lamp, alarm clocks w/sound machines, blackout curtains, ceiling fans, Smart TVs, ultra-quiet ACs, desk, chair & mirror.
4.98 out of 5 average rating, 101 reviews
New Cleveland Apt: Little Italy! Massage&Hot tub!
Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!
4.98 out of 5 average rating, 333 reviews
The Farmhouse - 1 Bdrm Apt in a Great Location
Welcome to this 2nd flr 1 bd/1 ba private apartment in a charming 1880s farmhouse located in a friendly walkable neighborhood. Full kitchen with all you need to make your own meals, washer/dryer and separate office inside the unit. Free off-street parking. You are only: 5 min walk to Starbucks, a variety of restaurants, bars, shops, trails 5-10 min drive to Cleveland Clinic, University Hospitals, Case Western, museums, parks, Little Italy and more 15 min drive to major attractions and Lake Erie
5.0 out of 5 average rating, 221 reviews
Little Italy Two Bedroom w/ Private Drive & Patio
Stay in the heart of Cleveland's historic Little Italy, one of the city's most vibrant and walkable neighborhoods. Restaurants, cafés, bakeries, galleries, and local markets are just steps away. Whether you're visiting Cleveland Clinic, University Hospitals, Case Western Reserve University, or exploring University Circle and Downtown Cleveland, you'll enjoy a stylish first-floor apartment with two private parking spaces, a fully equipped kitchen, a private patio, and room for up to six guests.
4.91 out of 5 average rating, 141 reviews
Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.
4.93 out of 5 average rating, 399 reviews
Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic
Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!
4.93 out of 5 average rating, 135 reviews
Charming Coventry Village Hampshire Rd (Lower)
Walk to Little Italy, CWRU/ Case. Cleveland Clinic 10 min Drive. Univ. Hosp. 15- 20 mins. to downtown-Quicken Loans Arena. One block to Coventry Rd. restaurants, shops, music venues, groceries,& family-friendly activities. You’ll love our place because of the privacy, Front Porch outdoor space and Tree Lined Street. Great for Families, business travelers, couples, and students. This is a family-owned home for over 30yrs. We have enjoyed opening our doors to people from all over the globe!
4.82 out of 5 average rating, 358 reviews
Private Victorian suite with two rooms and a bath
You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.
4.96 out of 5 average rating, 553 reviews
1BR in Little Italy, 5 min walk to Case & UH
Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.
4.93 out of 5 average rating, 100 reviews
Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.
4.98 out of 5 average rating, 559 reviews
Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled stay in this boho-chic apartment in the heart of Little Italy. Exposed brick, hardwood floors, and warm wooden furnishings create a comfortable and inviting space. Relax on the sofa, enjoy a meal in the cozy kitchen, and explore nearby restaurants, cafés, and shops—all within walking distance.The apartment is located on the second floor and requires one flight of stairs (17 steps). Free on-site parking is available for one car.
4.98 out of 5 average rating, 107 reviews
The Rapsodia in Blu of Little Italy *family run*
Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!
4.98 out of 5 average rating, 108 reviewsPopular amenities for family-friendly rentals near Case Western Reserve University
Family-friendly home rentals with a hot tub

Summit On Sixth – Skyline Views & Hot Tub
4.91 out of 5 average rating, 142 reviews
HotTub GameRoom Fenced EV PetsOK KingBeds KidLoft
5.0 out of 5 average rating, 135 reviews
Upscale-Lakefront-Private Beach-Hot Tub-King-Pets
5.0 out of 5 average rating, 124 reviews
Private 2 Level Apartment with Hot Tub in Tremont
4.88 out of 5 average rating, 525 reviews
Hot Tub! Ohio City Modern Luxury · 2 King Beds
4.94 out of 5 average rating, 125 reviews
Hot Tub - Game Room - Modern Design - Sleeps 9
4.94 out of 5 average rating, 126 reviews
Tremont Social Ranch | Hot Tub + Game Room
4.89 out of 5 average rating, 179 reviews
Planes, Trains and Automobiles
4.92 out of 5 average rating, 159 reviewsFamily- and pet-friendly home rentals

Gallery House | Near Clinic + Museums
4.82 out of 5 average rating, 246 reviews
The Studio at Gordon Square
4.85 out of 5 average rating, 715 reviews
Sunny Studio II / Private home next to Ray's MTB
4.97 out of 5 average rating, 220 reviews
Cozy house near Lake Erie, 10 minutes to Downtown.
4.97 out of 5 average rating, 345 reviews
Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #7
4.93 out of 5 average rating, 68 reviews
Historic Carriage House | Cleveland Heights
4.91 out of 5 average rating, 82 reviews
Cozy Comfortable Home close to Cleveland Clinic
4.92 out of 5 average rating, 63 reviews
Wizards - Hot Tub Pickleball Poker King Theater
5.0 out of 5 average rating, 5 reviewsFamily-friendly home rentals with a pool

Riverbend Retreat - Your Private Ohio Escape
4.91 out of 5 average rating, 115 reviews
Your home away from home!
4.93 out of 5 average rating, 159 reviews
Stylish Chic Downtown Apartment
4.93 out of 5 average rating, 107 reviews
2BR Lil’ Italy Retreat | Fast WiFi+Pets, W/D
4.78 out of 5 average rating, 37 reviews
Luxury Spa+Theater+Gameroom | CasaMora
5.0 out of 5 average rating, 70 reviews
Luxury Apt w/ Rooftop Pool, Hot Tub & Skyline View
4.95 out of 5 average rating, 56 reviews
Central Flat w/ Pool & Sauna • Gym • Heart of DT
5.0 out of 5 average rating, 20 reviews
Alizée | Stylish Studio Retreat Near Downtown CLE
4.91 out of 5 average rating, 33 reviewsFamily-friendly home rentals with wifi

Mid-Century Modern Retreat in Little Italy
4.96 out of 5 average rating, 53 reviews
Cozy Condo l Minutes from Cleveland Clinic
4.66 out of 5 average rating, 47 reviews
Green Historic House by Cle Clinic, CWRU, Museums
4.88 out of 5 average rating, 42 reviews
Easy Check-In 4 mins Cleveland Clinic CWRU Parking
5.0 out of 5 average rating, 20 reviews
Cleveland Clinic, 5 minutes from: South Suite
4.86 out of 5 average rating, 77 reviews
Contemporary Cedar-Lee Walkup
4.92 out of 5 average rating, 85 reviews
Relax at New Home & Walk to Cle Clinic
4.98 out of 5 average rating, 52 reviews
New Luxury Studios | Walk to Cleveland Clinic
4.85 out of 5 average rating, 147 reviewsQuick stats about family-friendly rentals near Case Western Reserve University

Total holiday rentals
Explore 40 holiday rentals in Case Western Reserve University

Nightly prices starting at
Case Western Reserve University holiday rentals start at £15 per night before taxes and fees

Verified guest reviews
Over 1,170 verified reviews to help you choose

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
40 of Case Western Reserve University holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Case Western Reserve University rentals

4.8 Average rating
Case Western Reserve University stays are highly rated by guests – averaging 4.8 out of 5!
Destinations to explore
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Gervasi Vineyard
- Headlands Beach State Park
- Cleveland Browns Stadium
- Cleveland Metroparks Zoo
- Mosquito Lake State Park
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- Laurentia Vineyard & Winery
- Cleveland Museum of Art
- The Arcade Cleveland
- Huntington Convention Center of Cleveland
- Crocker Park
- Debonné Vineyards
- Edgewater Park Beach
- JACK Cleveland Casino
- Rocky River Reservation
- Cleveland Museum of Natural History
- Greater Cleveland Aquarium





