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Family-friendly rentals near Case Western Reserve University

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals near Case Western Reserve University

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A two-family home is depicted with a front porch, featuring seating arrangements. The property is framed by a well-maintained garden, which includes blooming flowers and greenery. The exterior is characterized by a white siding and a rooftop with a unique gable design, set against a partly cloudy sky.
Home in University Circle

Gem in the heart of Little Italy! 3BR-DN

12/5 - 1/1/27 GUESTS MAY PARK IN DRIVEWAY! Enjoy your stay at this centrally located - lower unit- in a two-family home in Little Italy. Complete with a well-equipped kitchen. The living room includes comfortable seating for 6, smart TV, 3 poufs & coffee table - so ALL may rest their feet from a long day, modern furnishings & laundry room. Each bedroom includes USB plugs in the lamp, alarm clocks w/sound machines, blackout curtains, ceiling fans, Smart TVs, ultra-quiet ACs, desk, chair & mirror.

4.98 out of 5 average rating, 101 reviews
Guest favourite
A spacious outdoor area features a jacuzzi next to a dining table with chairs and an umbrella. Stone flooring surrounds the space, while a brick wall provides a rustic backdrop. Decorative lighting adds a calming touch to the environment.
Holiday home in University Circle

New Cleveland Apt: Little Italy! Massage&Hot tub!

Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!

4.98 out of 5 average rating, 333 reviews
Top guest favourite
A bright living room features a cozy orange sofa paired with two armchairs adorned with patterned cushions. A wooden coffee table sits in the center, complemented by a decorative rug. Natural light filters through the windows, enhancing a welcoming atmosphere.
Flat in Cleveland Heights

The Farmhouse - 1 Bdrm Apt in a Great Location

Welcome to this 2nd flr 1 bd/1 ba private apartment in a charming 1880s farmhouse located in a friendly walkable neighborhood. Full kitchen with all you need to make your own meals, washer/dryer and separate office inside the unit. Free off-street parking. You are only: 5 min walk to Starbucks, a variety of restaurants, bars, shops, trails 5-10 min drive to Cleveland Clinic, University Hospitals, Case Western, museums, parks, Little Italy and more 15 min drive to major attractions and Lake Erie

5.0 out of 5 average rating, 221 reviews
Guest favourite
Flat in University Circle

Little Italy Two Bedroom w/ Private Drive & Patio

Stay in the heart of Cleveland's historic Little Italy, one of the city's most vibrant and walkable neighborhoods. Restaurants, cafés, bakeries, galleries, and local markets are just steps away. Whether you're visiting Cleveland Clinic, University Hospitals, Case Western Reserve University, or exploring University Circle and Downtown Cleveland, you'll enjoy a stylish first-floor apartment with two private parking spaces, a fully equipped kitchen, a private patio, and room for up to six guests.

4.91 out of 5 average rating, 141 reviews
Top guest favourite
A modern kitchen area features gray cabinetry and a stainless steel sink, complemented by a sleek, dark countertop. A black stove and microwave are seen, alongside a refrigerator with a textured finish. White tiles line the backsplash, reflecting light from the overhead fixture.
Home in University Circle

Historic Little Italy Garden Apartment

Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

4.93 out of 5 average rating, 399 reviews
Top guest favourite
The living area features a spacious layout with an orange sectional sofa, a circular coffee table, and a light-colored area rug. Natural light filters through large windows, illuminating the space. A 59" smart TV is positioned across from the seating area, providing a comfortable environment for relaxation.
Flat in Cleveland

Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic

Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!

4.93 out of 5 average rating, 135 reviews
Guest favourite
A front porch area is presented with wooden furniture, including a small table and chairs, a decorative bench, and a woven chair. A cozy rug is laid on the floor, surrounded by greenery from nearby plants, creating a relaxed outdoor space.
Home in Cleveland Heights

Charming Coventry Village Hampshire Rd (Lower)

Walk to Little Italy, CWRU/ Case. Cleveland Clinic 10 min Drive. Univ. Hosp. 15- 20 mins. to downtown-Quicken Loans Arena. One block to Coventry Rd. restaurants, shops, music venues, groceries,& family-friendly activities. You’ll love our place because of the privacy, Front Porch outdoor space and Tree Lined Street. Great for Families, business travelers, couples, and students. This is a family-owned home for over 30yrs. We have enjoyed opening our doors to people from all over the globe!

4.82 out of 5 average rating, 358 reviews
Top guest favourite
A welcoming entrance leads to a sunny sitting room featuring a blue sofa beside a wooden rocking chair. A small side table with a lamp is visible near a large window framed by soft curtains, allowing natural light to enter the space.
Guest suite in Cleveland Heights

Private Victorian suite with two rooms and a bath

You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.

4.96 out of 5 average rating, 553 reviews
Guest favourite
Flat in University Circle

1BR in Little Italy, 5 min walk to Case & UH

Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.

4.93 out of 5 average rating, 100 reviews
Top guest favourite
The exterior of a charming brick carriage house is showcased, featuring a steeply pitched roof and large, shuttered windows. Lush greenery surrounds the entrance, with flowering plants visible near the driveway, providing a welcoming ambiance on the sunlit day.
Guest house in Cleveland Heights

Clean and Cozy Carriage House Getaway

Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

4.98 out of 5 average rating, 559 reviews
Top guest favourite
Flat in University Circle

Little Italy 3, close to Cleveland Clinic, CWRU

Enjoy a uniquely styled stay in this boho-chic apartment in the heart of Little Italy. Exposed brick, hardwood floors, and warm wooden furnishings create a comfortable and inviting space. Relax on the sofa, enjoy a meal in the cozy kitchen, and explore nearby restaurants, cafés, and shops—all within walking distance.The apartment is located on the second floor and requires one flight of stairs (17 steps). Free on-site parking is available for one car.

4.98 out of 5 average rating, 107 reviews
Top guest favourite
The living and dining area features a plush sofa with decorative pillows, a coffee table, and a dining table set for four. Light filters through sheer curtains, complemented by warm lighting from a stylish lamp. The kitchen is visible with pastel cabinetry and appliances.
Flat in University Circle

The Rapsodia in Blu of Little Italy *family run*

Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!

4.98 out of 5 average rating, 108 reviews

Popular amenities for family-friendly rentals near Case Western Reserve University

Quick stats about family-friendly rentals near Case Western Reserve University

  • Total holiday rentals

    Explore 40 holiday rentals in Case Western Reserve University

  • Nightly prices starting at

    Case Western Reserve University holiday rentals start at £15 per night before taxes and fees

  • Verified guest reviews

    Over 1,170 verified reviews to help you choose

  • Pet-friendly holiday rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    40 of Case Western Reserve University holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Case Western Reserve University rentals

  • 4.8 Average rating

    Case Western Reserve University stays are highly rated by guests – averaging 4.8 out of 5!