Guest house holiday rentals in Charleston County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Charleston County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Charleston County
Family-friendly guest house rentals
Guest house in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
31 Jan – 7 Feb
Guest house in Summerville
4.98 out of 5 average rating, 643 reviews★Delightful guest house near historic plantations★
16–23 Dec
Guest house in North Charleston
5.0 out of 5 average rating, 110 reviewsThe Park Circle Clerestory Studio Guest House
2–9 Jul
Guest house in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
19–26 Dec
Guest house in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
16–23 Aug
Guest house in Mount Pleasant
4.95 out of 5 average rating, 220 reviewsGreen Garden Studio @greengardenstudio2017
3–10 Oct
Guest house in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
21–28 Oct
Guest house in Summerville
4.87 out of 5 average rating, 748 reviewsNew Loft in Historic Summerville
3–10 Nov
Guest house rentals with a patio
Guest house in Charleston
4.98 out of 5 average rating, 122 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
26 Feb – 5 Mar
Guest house in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
25 Dec – 1 Jan
Guest house in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
2–9 Aug
Guest house in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
18–25 Jun
Guest house in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
6–13 Aug
Guest house in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
10–17 Mar
Guest house in Charleston
4.94 out of 5 average rating, 78 reviewsSpacious 1 bedroom cottage in Avondale
17–24 Aug
Guest house in Charleston
5.0 out of 5 average rating, 12 reviewsLowcountry Guesthouse
15–22 Jul
Guest house rentals with a washing machine and dryer
Guest house in Charleston
4.99 out of 5 average rating, 141 reviewsLarge Guesthouse with Private Dock & Marsh Views
26 Jul – 2 Aug
Guest house in Mount Pleasant
4.98 out of 5 average rating, 436 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
2–9 Nov
Guest house in Charleston
4.99 out of 5 average rating, 206 reviewsRedesigned suite! 12min to city, pet-friendly
15–22 Dec
Guest house in Charleston
5.0 out of 5 average rating, 143 reviewsThe Guesthouse at Old Orchard
10–17 Sept
Guest house in Mount Pleasant
4.99 out of 5 average rating, 248 reviewsUpscale Couple's Escape | Beach & Downtown CHS
5–12 Jul
Guest house in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
25 Aug – 1 Sept
Guest house in Charleston
4.9 out of 5 average rating, 548 reviewsCute, Cozy, Charleston Cottage
28 Aug – 4 Sept
Guest house in Charleston
4.96 out of 5 average rating, 236 reviewsUnique Hidden Gem w/ Luxury Shower Near Folly & DT
9–16 Jan
Destinations to explore
- Guest house rentals United States
- House rentals United States
- House rentals Myrtle Beach
- House rentals Charleston
- Guest house rentals Charleston
- House rentals Savannah
- Guest house rentals Savannah
- House rentals South Carolina
- Guest house rentals South Carolina
- Rentals with beach access Charleston County
- Rentals with a washing machine and dryer Charleston County
- Townhouse rentals Charleston County
- Luxury rentals Charleston County
- Rentals with breakfast Charleston County
- Pet-friendly rentals Charleston County
- Tiny house rentals Charleston County
- Rentals with a patio Charleston County
- Villa rentals Charleston County
- Rentals with a kayak Charleston County
- Bungalow rentals Charleston County
- Flat rentals Charleston County
- House rentals Charleston County
- Rentals with pools Charleston County
- Rentals with a hot tub Charleston County
- Apartment rentals Charleston County
- Bed and breakfasts Charleston County
- Family-friendly rentals Charleston County
- Rentals with a fireplace Charleston County
- Rentals with lake access Charleston County
- Private suite rentals Charleston County
- Beachfront rentals Charleston County
- Rentals with an accessible-height toilet Charleston County
- Fitness-friendly rentals Charleston County
- Rentals with outdoor seating Charleston County
- Rentals with an EV charger Charleston County
- Waterfront rentals Charleston County
- Monthly Rentals Charleston County
- Rentals with a firepit Charleston County
- Family-friendly rentals Charleston County
- Hotel rentals Charleston County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom