
Holiday rentals in Colón Province
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Top-rated holiday rentals in Colón Province
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Clubhouse
Wake up overlooking the lake in Cerro Azul, where nature and design come together in perfect harmony. This modern house offers 4 bedrooms with en-suite bathrooms and 2 guest bathrooms, making it ideal for special celebrations, intimate weddings, or unforgettable gatherings with family and friends. Its open-plan, industrial-style kitchen blends in with the spacious rooms and a terrace that merges with the landscape. The master suite, featuring a hot tub, invites you to unwind and reconnect with yourself.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

The Bird's Nest in the Clouds
Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Entire Villa with pool in front of beach!
Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

KasaKai garden floor - amazing views over the sea
Caribbean downstairs apartment with amazing sea view. Surrounded by wildlife. This property has a private access to the Caribbean Sea. The house is situated over a 2 miles long reef. Amazing snorkeling, there are many naturals pools into the reef where you can snorkel. Ideal for kids! There is a jungle behind the house which makes that you will hear the monkey from the house.

Luxury Centric 2BR Apartment in Casco Viejo
Welcome to our charming and spacious apartment in the heart of Casco Viejo. We are located directly across the street from the landmark Hotel La Compañia. From the balcony you can look at the remaining structure of the centuries-old La Compañia de Jesus, a former Jesuit temple and convent. In the apartment, you can relax in the spacious and comfortable space.
Popular amenities for Colón Province holiday rentals
Other great holiday rentals in Colón Province

Most Beautiful Loft in the Heart of Casco Viejo

BirdHouse@ Gamboa Panama Canal

Mediterranean House Punta Chame

Casa "El Terrenito" - Ocean Front

Charming apartment with a view of the Caribbean Sea

w* | Luxury 2BR in Old Town

The Crystal House: Luxury Modern Wood Cabin

Casa Condal - Your Private Nature Eco-Retreat
Destinations to explore
- Smoking-friendly rentals Colón Province
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