
Holiday rentals in Panama
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

Cozy open space, unique jungle views, river access
Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

On the Beach Villa in Boca Chica!
Contemporary on the beach Villa with 180° Panoramic Ocean & island views of the Gulf of Chiriqui National Park. Open concept, indoor/outdoor living with private pool & spacious terraces for lounging, sunsets & stargazing. Perched on a cliff with direct beach access. Ocean breezes, tropical birds, exotic monkeys, iguanas & dolphins in the Bay. Private gated community. Large sand beach, perfect for swimming, boogie boarding, long walks, bocce ball or just relaxing & enjoying the sounds of nature.

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Torio guesthouse with panoramic view
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO
The name of the Complex comes from the world-renowned architect and interior designer, Marcel Wanders. He had the idea to accentuate the flora and fauna of Panama and bring a relaxed sensation even though the complex is located in the middle of the city. This unit in particular has the most detailed pick on designer furniture from brands such as Herman Miller and Restoration Hardware. The kitchen is also fully equipped with Thermador appliances so you can live the Wanders & Yoo experience.

Beach House-Amazing Pool, Surf & Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with solar and battery backup systems.

Cocovivo Snoozy Sloth
Private waterfront cabin with one luxurious king-sized bed and dock with spectacular views of our coral-filled bay. When night falls, sparkling bioluminescent waters makes this cabin seem like it's out of a fairy tale. A flourishing coral reef aligns the whole property for snorkeling, kayak or SUP expeditions! Did I mention we have a shipwreck too? "Jetsons-meet-Flintstones" is the vibe here. Please read the “Other things to note” section so you know what to expect!

Escape to the Heart of Casco with a Private Balcony
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Beautiful Apartment 3 guests
Moderno, elegante y cómodo departamento, cerca de todo! Restaurantes, farmacias, supermercados, canchas de padle, a pocos minutos del centro comercial Multiplaza. Totalmente amoblado, 1 recamara, 1 baño completo, walking closet, cocina, sala, área de desayunador, lavadora-secadora y balcón. Para su disfrute, piscina de agua salada en el último piso, gimnasio, espacio de co-working, incluye un espacio de estacionamiento con valet parking.

Casa De Ola, Jungle Beach Cabin
Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.

King Bed, Creative Design Steps from Casco Viejo
Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
Popular amenities for Panama holiday rentals
Other great holiday rentals in Panama

A Modern & Cozy Apartment In Prime Location

Ocean View Studio Queen bed & pool

New apartment on 50th Street

Unique Luxury 3-story Loft at the Yoo

Luxury apartment in the Panamá city

Ocean View Apartment on the Coastal Belt

Luxury Mid-Century Apartment In Casco Viejo

Pedasí, Los Destiladeros Beach / Casa Serena
Destinations to explore
- Rentals with beach access Panama
- Rentals with an accessible-height bed Panama
- Rentals with a cinema Panama
- Bungalow rentals Panama
- Rentals with a firepit Panama
- Pet-friendly rentals Panama
- Nature eco lodge rentals Panama
- Rentals with breakfast Panama
- Dome rentals Panama
- Tent rentals Panama
- Villa rentals Panama
- Townhouse rentals Panama
- Beach house rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Chalet rentals Panama
- Bed and breakfasts Panama
- House rentals Panama
- Island rentals Panama
- Rentals with a hot tub Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Cottage rentals Panama
- Fitness-friendly rentals Panama
- Rentals with lake access Panama
- Apartment rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Boutique hotel rentals Panama
- Boat rentals Panama
- Treehouse rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with a sauna Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Aparthotel rentals Panama
- Hotel rentals Panama
- Loft rentals Panama
- Flat rentals Panama
- Lakehouse rentals Panama
- Rentals with pools Panama
- Waterfront rentals Panama
- Rentals with a patio Panama
- Smoking-friendly rentals Panama
- Tiny house rentals Panama
- Farm stay rentals Panama
- Family-friendly rentals Panama