
Holiday rentals in Panama
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Private Catamaran live on board
Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Cozy open space, unique jungle views, river access
An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Bocas del toro - Villa over the water- Bahia Coral
Come and live a unique experience, in our Ecolodge on stilts, you will experience dream moments in the bay of Punta Caracol, a heavenly place between sky and sea. Our EcoBungalow 4-6 people, offers two bedrooms with King size bed, two bathrooms, an equipped kitchen, the lounge area turns into a third sleeping area. 15 minutes by boat from the center of Bocas, 10 minutes by boat from Playa Estrella, you can easily enjoy the treasures of the archipelago.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Cocovivo Mangrove Tree house
This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Boquete Bees and Butterflies Casitas
Butterfly exhibit and breakfast included, 2 hectares of fabulous gardens full of colorful birds and a collection if stingless honey bees. Close to town. Forms part of a honey farm offering more than 24 types of honey, a great store and bee and honey tasting tours also part of a traditional Boquete Coffee Estate. We can accommodate 4 px but booking price including breakfast is for 2px. We charge an additional $15 per person.

New World Casita @ Finca Panda
Mundo Novo is one of our new, one-room casitas and has one of the most incredible views on the property. Perfect for couples, singles or family with a small child, Geisha sleeps 2 people comfortably in one king bed (maximum 3 guests when using sofa). Geisha was designed with every amenity needed to have a perfect and relaxing stay. Custom-built jacuzzi, fire-pit, kitchen, incredible shower, high-speed WiFi and more

Coffee Cabins - Cabin 2
Welcome to the Coffee Cabins. This is one of four stunning A-frame cabins perched on the side of a mountain in the middle of a coffee field. You’re literally surrounded by coffee, both on the trees and in your kitchen with the complimentary coffee grown right here on the farm. Enjoy larger than life views to both the north towards the continental divide and to the west framing Volcan Baru, Panama’s highest peak.

Casita BarrBra BnB
La Casita Barrbra BnB Nestled above the Caribbean waters in Bocas del Toro, discover our tiny house, an extension of the iconic Barrbra BnB. Located in a lively neighborhood, it's just minutes from the center and a 5-minute walk from a supermarket. Wake up to the ocean at your feet and the authentic charm of Bocas all around. Combining comfort with immersion in local life, this experience will enchant you.
Popular amenities for Panama holiday rentals
Other great holiday rentals in Panama

Casa De Ola, Jungle Beach Cabin

Most Beautiful Loft in the Heart of Casco Viejo

Fobos – Luxury 1-Bed Cabin with Heated Pool

Bocas Overwater Luxury Villa & Lodge

Carenero Hills 3 - Beach & Surf Bungalows.

Casco Antiguo Apartment with Balcony & Stone Wall

Casa Indigo Eco-Paradise over the sea! (Off-Grid)

Bahari Bocas - Bungalow 1
Destinations to explore
- Beach apartment rentals Panama
- Pet-friendly rentals Panama
- Lakehouse rentals Panama
- Rentals with breakfast Panama
- Rentals with an accessible-height bed Panama
- Rentals with a cinema Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Rentals with a sauna Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Nature eco lodge rentals Panama
- Rentals with a patio Panama
- Rentals with beach access Panama
- Smoking-friendly rentals Panama
- Boutique hotels Panama
- Loft rentals Panama
- Chalet rentals Panama
- Bungalow rentals Panama
- Bed and breakfasts Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Cottage rentals Panama
- Townhouse rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Tent rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a firepit Panama
- Fitness-friendly rentals Panama
- Holiday home rentals Panama
- Dome rentals Panama
- Family-friendly rentals Panama
- Treehouse rentals Panama
- Apartment rentals Panama
- Flat rentals Panama
- Rentals with lake access Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- House rentals Panama
- Rentals with a hot tub Panama
- Farm stay rentals Panama
- Beach house rentals Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Island rentals Panama
- Villa rentals Panama
- Waterfront rentals Panama
- Boat rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Tiny house rentals Panama
- Rentals with pools Panama





