
Apartment holiday rentals in Colón Province
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Colón Province
Guests agree: these apartments are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Best location - Unique and charming loft
Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Spacious 4Br Beachside Getaway at Playa Escondida
Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Beachfront Paradise at a 5-star resort
Vacaciones perfectas en el Caribe Panameño . A solo 1 h de Ciudad de Panamá . Este resort privado de Arena Blanca y Aguas Turquesa es tu paraíso más cercano con Acceso a Islas privadas a través de Muelle , Pádel , Piscina infinita , Juegos de Niños , Restaurantes y Bar . Precioso y cómodo Apartamento con Vista al Mar , Acceso autónomo , Amplia Sala y Comedor , Terraza , Cocina completa , 3 Habitaciones , 5 camas , 2 Baños completos , A/C y Wifi , 8 huéspedes máx .

Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Casco Antiguo Apartment with Balcony & Stone Wall
Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

KasaKai Penthouse · Caribbean Sea View· Beachfront
This exclusive beachfront penthouse offers one of the closest true beach experiences from Panama City. Wake up to panoramic Caribbean Sea views, enjoy direct private access to the water, and relax in your own green outdoor area, ideal for quiet moments or private barbecues. Perfect for travelers seeking privacy, comfort, and nature, this penthouse combines a unique feet-in-the-water experience with high-end amenities, creating an unforgettable seaside stay.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
Popular amenities for Colón Province apartment rentals
Weekly apartment rentals

Luxury Centric 2BR Apartment in Casco Viejo

Luxury apt in Panama City 2 Rooms 3 Baths

Amazing loft with Casco charm in the best location

Villas La Fontana Spacious ApartaSuite - Pool 104

Casco Antiguo Apartment, Panama

Sunrise Caribbean at Playa Escondida Resort & Marina

Cozy Apartment in the Heart of Casco Viejo

A warm and cozy flat in Casco Viejo
Private apartment rentals

GreatCanal-Front Luxury 3BR | City & Golf View 401

A cozy Casco Viejo apartment

Centric - 2BDR Apt - Old Town

Luxury Beach Escape · Playa Escondida Resort

Tropicool Casco Loft w/King Bed & Rooftop

Charming Casco Viejo Flat with Parking and Pool

Playa Escondida Apartment with Ocean View

Panama City Sea View
Apartment rentals with a hot tub

Ocean View - Playa Escondida Resort

New Flat with Ocean + City Views

Ocean View Apt in Panama, Yoo&Arts

Apartment in a hidden beach

Tropical Paradise at Playa Bonita

Marina, Oceanfront, Private Pool, Ground Floor

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Amazing apartment in Playa Escondida Resort
Destinations to explore
- Smoking-friendly rentals Colón Province
- Rentals with a sauna Colón Province
- Rentals with a fireplace Colón Province
- Guest house rentals Colón Province
- Rentals with lake access Colón Province
- Bed and breakfasts Colón Province
- Rentals with a kayak Colón Province
- Family-friendly rentals Colón Province
- Rentals with a firepit Colón Province
- House rentals Colón Province
- Rentals with outdoor seating Colón Province
- Pet-friendly rentals Colón Province
- Chalet rentals Colón Province
- Rentals with a washing machine and dryer Colón Province
- Private suite rentals Colón Province
- Boutique hotels Colón Province
- Nature eco lodge rentals Colón Province
- Apartment rentals Colón Province
- Villa rentals Colón Province
- Rentals with a patio Colón Province
- Beachfront rentals Colón Province
- Rentals with breakfast Colón Province
- Tiny house rentals Colón Province
- Hostel rentals Colón Province
- Cottage rentals Colón Province
- Townhouse rentals Colón Province
- Waterfront rentals Colón Province
- Serviced apartment rentals Colón Province
- Holiday home rentals Colón Province
- Container rentals Colón Province
- Loft rentals Colón Province
- Rentals with a hot tub Colón Province
- Rentals with an EV charger Colón Province
- Rentals with beach access Colón Province
- Cabin rentals Colón Province
- Hotel rooms Colón Province
- Rentals with a cinema Colón Province
- Rentals with an accessible-height bed Colón Province
- Fitness-friendly rentals Colón Province
- Ski-in/ski-out rentals Colón Province
- Rentals with pools Colón Province
- Flat rentals Panama
- Things to do Colón Province
- Sports activities Colón Province
- Nature and outdoors Colón Province
- Food and drink Colón Province
- Tours Colón Province
- Art and culture Colón Province
- Sightseeing Colón Province
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Entertainment Panama
- Food and drink Panama
- Art and culture Panama





