
House holiday rentals in Doña Ana
Find and book unique houses on Airbnb
Top-rated house rentals in Doña Ana
Guests agree: these houses are highly rated for location, cleanliness and more.

Bonita Casita
This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Comfortable, relaxing home.
This home has a comfortable open floorplan w/plenty of seating around the kitchen breakfast bar & dining table. This kitchen welcomes you with beautiful long island & stainless steel appliances, supplied with dishes, pots, pans, utensils, Keurig machine. Home boasts 3 queen size beds & a room for an office w/a desk or playroom for kids. HIGH-SPEED WIFI w/ XFINITY. Reclining couches in the Living room.Shopping & a variety of restaurants, Red Hawk Golf, Parks, Fitness One, White Sands close by.

Conway Cottage 2
Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Luxury Southwest Retreat
Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Modern Luxury Home
This Luxury Modern Home is made to suit all guests! Whether you are looking for a weekend getaway or a place for work and play, this home has everything to offer in beautiful Las Cruces, NM. Located in a brand new neighborhood near Red Hawk Golf Course and multiple family-friendly parks. Guests can rest peacefully in one of 4 bedrooms and enjoy amenities such as an outdoor grill, outdoor living area, lawn games, board games, and most kitchen items. High-speed Internet included and SmartTVs.

Casa Miranda, The Organ Mountains Looking House
Experience your clean, comfortable & spacious Southwestern home in Las Cruces, NM, now with a brand new refrigerated AC system. Your home has wonderful amenities: a fully stocked kitchen, washer/dryer, iron, comfortable beds (king & queen size), 65' flat screen TV in the living room with Wifi, secure two car garage, and a backyard with a breathtaking view of The Organ Mountains. Located minutes from both I-25/ US-70, easily get to downtown, Mesilla, NMSU, White Sands, and The Lincoln Forest.

Cheerful desert oasis hot tub/fam/pet friendly!
We welcome all looking for a comfortable stay in a quiet, safe neighborhood! Centrally-located 1 min from the new hospital close to baseball/soccer/football parks, urgent care, emergency room, grocery stores, food places, convenience stores, and gas stations. Conveniently 2 minutes from I-10 , I-25 and Highway 70. Old Town Mesilla and NMSU are only 12 minutes away! White Sands is 45 minutes! Organ mountains, Soledad Canyon and Dripping Springs is a must while you are visiting Las Cruces!

Historic Adobe Home- Libélula (Dragonfly)
Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A 5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

VIGIL-INN High Desert Escape in Quiet Neighborhood
**Extend your stay to get special Weekly and Monthly Pricing**Get a change of scenery and come experience the openness of the High Desert. Outdoor activities abound with nearby walking paths, tennis courts, and parks. Find plenty of space to get out and explore local mountain trails and White Sands National Park all within an hours drive. Modern conveniences such as Starbucks and food establishments are within a 5 minute drive. No pets, no parties and no smoking please!

Modern Accessorized 3-Bedroom
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With latest in appliances and style, the Powder River Villa offers the comfort of home with a luxury feel. Stream Netflix in front of the stacked stone fireplace, decompress in the pebble rain shower, or simply relax on the back porch to the beautiful New Mexico sunsets. This stylish space can be the romantic escape you're seeking or comfortably fit your group of 7.

La Casita Bonita - Garage with EV Charger!
If you're seeking a cozy retreat with abundant outdoor living space, look no further than La Casita Bonita in beautiful Las Cruces, NM! This charming property is ideally located just minutes from I-25/US-70, offering easy access to downtown, Mesilla, NMSU, and White Sands. Thoughtfully designed with your comfort in mind, this fully stocked townhouse has everything you need to feel at home. We look forward to hosting you soon!

Mountain View luxury Gem!Pet Friendly!HotTub!EV!
Located in the upscale Sonoma Ranch Country Club community, located only 300 yards from the Club house and Sunset Grill! This home has amazing Mountain View’s with a large 6 person hot tub as well as an 85 inch TV with a Bose system for movie nights! Also available is a 2 car garage with Tesla charger! Minutes away from shopping, NMSU and hospitals!
Popular amenities for house rentals in Doña Ana
House rentals with a pool

Luxury Home- Pool, Views, Early Check in

Las Cruces SW Charm w/ Pool, Hot Tub & Mtn Views!

Heated Pool HotTub GameRoom Views Near White Sands

Family-Friendly Escape with Pool & Play Area

Desert Paradise, with hot tub

Luxury Oasis Best Location • PingPong • CoffeeBar

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Oasis with Pool
Weekly house rentals

Desert Oasis with Stunning Views

Valley View Getaway Home

MidTown- Washer and dryer- full kitchen-

Turquoise Casita w/ King Bed

*3BR Farmhouse Home | Bright, Peaceful & Cozy Stay

Entire Home- Vista Montaña (your White Sands Base)

Spacious Mountain-View Home, 45 min to White Sands

Apache’s Retreat w/ HOT TUB & Pool table
Private house rentals

Desert Silhouette

Elite Casita w/ indoor Jet Tub & EV

Hurley's house

Cozy Las Cruces Home

Las Cruces, New 4 BR home, Pickle ball, Vacation!

Organ Mountain Loft| 3BR| Movie Room

Pachamama Haven §

3 Bedroom, full house, back yard
Destinations to explore
- Salt River Holiday rentals
- Tucson Holiday rentals
- El Paso Holiday rentals
- Northern New Mexico Holiday rentals
- Albuquerque Holiday rentals
- Ruidoso Holiday rentals
- Mesa Holiday rentals
- Santa Fe Holiday rentals
- Ciudad Juárez Holiday rentals
- Chihuahua Holiday rentals
- Lubbock Holiday rentals
- Chandler Holiday rentals
- White Sands National Park
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- Western Playland
- El Paso Chihuahuas
- Dripping Springs Natural Area
- New Mexico Farm & Ranch Heritage Museum
- El Paso Museum of Art
- Parque Público Federal El Chamizal
- San Jacinto Plaza
- El Paso Zoo
- Southwest University Park
- Sunland Park Racetrack & Casino
- Farmers And Crafts Market of Las Cruces




