Holiday rentals in Isthmus of Panama

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Top-rated holiday rentals in Isthmus of Panama

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite

Cabin in Torio, Panama

4.97 out of 5 average rating, 99 reviews

Cozy open space, unique jungle views, river access

Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

27 Feb – 6 Mar

£99 per night

Guest favourite

Flat in Panamá

5.0 out of 5 average rating, 61 reviews

Cozy n Comfy con balcón in the heart of Casco

Remodelado, cómodo y céntrico alojamiento en el corazón de Casco Viejo, pintoresco lugar declarado Patrimonio de la Humanidad por la UNESCO. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. Podrás explorar la zona a pie, el apartamento esta completamente remodelado, un balcón espectacular, cocina full equipada, camas cómodas, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar-Smart tv -Cocina full equipada -1.5 baños -Balcón con vistas

22–29 Mar

£107 per night

Guest favourite

Guest house in Torio

4.91 out of 5 average rating, 109 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

15–22 Jul

£66 per night

Guest favourite

Villa in Río Hato, Panama

5.0 out of 5 average rating, 38 reviews

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Welcome to one of the nicest villas in Buenaventura, Panama's most luxurious beach resort community. This meticulously kept, spacious, 4 bedroom vacation paradise with additional private guest house and pool will make for unforgettable getaways with family and loved ones. Private baths, multiple dining areas, Sonos indoor/outdoor sound system, gorgeous outdoor areas and high end finishes, furnishings, and appliances throughout make every moment spent in Las Portales one to treasure.

30 Jun – 7 Jul

£413 per night

Superhost

Earthen home in El Cope, Penonome

4.91 out of 5 average rating, 145 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

9–16 Apr

£178 per night

Guest favourite

Townhouse in Panamá

4.97 out of 5 average rating, 161 reviews

Casa Casco Amigos - The Only House in Casco.

Located by the French Embassy in Casco Viejo in the absolute safest and most prestigious area of Panama City, Casa Casco Amigos is a 3 level, 3 bedroom 351 square meter house with a roof terrace and a garden terrace which can sleep 9. Despite the liveliness of the area, there is no noise whatsoever in the bedrooms. Perfect for 1 or 2 families, or a group of 6 to 9 friends who want to be in the heart of the old city, with a sea view and many areas to lounge and avoid the midday heat.

22 Feb – 1 Mar

£302 per night

Guest favourite

Earthen home in Punta Cocles, Costa Rica

4.98 out of 5 average rating, 116 reviews

Étnico Villas - Casa Cabécar / 3min from the beach

Located in a safe neighborhood, in one of the best beaches of the caribbean of Costa Rica. Étnico Villas offers exclusive cabins completely furnished, thought for couples or independant persons. Decorated with exotic ethnic touches, built with mostly natural materials like wood and clay localy sourced. Sourrended by beautiful and exuberant tropical gardens, with lush vegetation and wild animals. Only 3 minutes walking from the beach, close to supermarkets, restaurants and services.

10–17 Sept

£98 per night

Guest favourite

Loft in Panamá, Panama

4.92 out of 5 average rating, 177 reviews

Amazing Loft with the Best view of Casco viejo!

Hermoso loft ubicado en el centro de Casco Antiguo, la zona más turística de Panamá. Ven, disfruta y relájate en este impresionante loft, con una vista increíble de la Catedral de Panamá. Puedes visitar museos, bares, restaurantes e iglesias ubicados a tan solo unos cuantos metros de distancia. Beatiful Loft located in the center of Casco Antiguo, Panama´s most turistic location. Come, enjoy and relax at this amazing loft, with amazing view to Panama´s Cathedral.

11–18 Apr

£94 per night

Superhost

Treehouse in Provincia de Bocas del Toro

4.92 out of 5 average rating, 200 reviews

Cocovivo Mangrove Treehouse +transportation!

This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

23–30 Oct

£114 per night

Guest favourite

Home in Playa Mata Oscura

4.92 out of 5 average rating, 24 reviews

Casa De Ola, Jungle Beach Cabin

Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.

21–28 Mar

£155 per night

Superhost

Treehouse in Isla Colon

4.95 out of 5 average rating, 130 reviews

Secret Jungle Treehouse by the Sea

A 2 bedroom treehouse built around a huge tree overlooking the lush jungle in a hidden setting. Artistically designed & comfortable; welcoming romantic souls, nature lovers & the adventurous. Enjoy nature in the harmony of an eco environment; ocean breezes, sound of waves, birds & monkeys. Spectacular sandy beaches only steps away. Surf, swim, bike, explore & live the adventure!. YouTube « Jungle Treehouse by the sea »

27 Sept – 4 Oct

£221 per night

Superhost

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 224 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets.

22–29 Jun

£525 per night