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Holiday rentals in Isthmus of Panama

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Top-rated holiday rentals in Isthmus of Panama

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Top guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 112 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Top guest favourite
Home in San Vito
5 out of 5 average rating, 9 reviews

Private 40-Acre Hacienda Estate

Our Hacienda sits on 40 Acres of land that was once one of the areas original Coffee plantations. Today, it is a private Estate with big jungle trees, about 4km of trails, fruit orchards and beautiful gardens. The house has been fully renovated and is welcoming and comfortable. A large wrap-around terrace looks out toward Volcán Barú and La Amistad Park. Hacienda Viva offers a setting to slow down and reconnect. Our place offers something for everyone..a perfect place to enjoy and make Memories!

Top guest favourite
An open living space features a wooden dining table surrounded by six wicker chairs. Two hanging hammocks are displayed on the covered terrace, offering views of the lush hills. Large glass doors reflect the greenery, blending indoor and outdoor spaces harmoniously.
Cabin in Torio
4.97 out of 5 average rating, 179 reviews

Cozy open space, unique jungle views, river access

An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

Top guest favourite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
4.98 out of 5 average rating, 56 reviews

FACING THE SEA Cacique (Portobello Park)

A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.81 out of 5 average rating, 318 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.95 out of 5 average rating, 212 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favourite
Home in Altos del Maria
4.75 out of 5 average rating, 140 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 13 reviews

Luxury Balcony Stays + Pool Casco Viejo

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Top guest favourite
Flat in Panama City
4.97 out of 5 average rating, 112 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favourite
The modern house is surrounded by lush greenery, featuring a spacious wooden deck with lounge chairs and a private pool. Sliding glass doors enhance the connection with nature, while a covered terrace provides shaded seating areas for relaxation.
Home in Playa Venao
4.92 out of 5 average rating, 72 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Top guest favourite
An aerial view captures the lush greenery surrounding the treehouse, which extends over tranquil waters. The vibrant blue and green hues of the lagoon contrast with the shoreline, showcasing the natural beauty of the area. Mangroves frame the water's edge, emphasizing the secluded environment.
Treehouse in Provincia de Bocas del Toro
4.93 out of 5 average rating, 253 reviews

Cocovivo Mangrove Tree house

This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Top guest favourite
Cabin in Jaramillo
5 out of 5 average rating, 31 reviews

Coffee Cabins - Cabin 2

Welcome to the Coffee Cabins. This is one of four stunning A-frame cabins perched on the side of a mountain in the middle of a coffee field. You’re literally surrounded by coffee, both on the trees and in your kitchen with the complimentary coffee grown right here on the farm. Enjoy larger than life views to both the north towards the continental divide and to the west framing Volcan Baru, Panama’s highest peak.

Popular amenities for Isthmus of Panama holiday rentals