
Holiday rentals in La Mesa
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in La Mesa
Guests agree: these stays are highly rated for location, cleanliness and more.

Desert Oasis with Pool
Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Ocotillo Casita in Historic Mesilla.
Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

La Union Penthouse Apartment
Just remodeled and updated! Originally designed by Contemporary Artist, Willie Ray Parish. A huge, paradoxically cozy space, ideal for the traveling couple with a single Queen sized bed; it occupies approximately 1600 square feet on the top floor of a former cotton gin warehouse surrounded by a 2-acre Permaculture experiment. It is the private "Penthouse Apartment" amidst multiple communal and shared spaces on the property. Creative touches everywhere you look. A truly unique experience.

Raven's House
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Little House with Private Patio and Hot Tub
Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

1 bed cute casita near NMSU, pet friendly
Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV
Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Sombra Del Valle in Historic Mesilla.
Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

4 Bedroom Contemporary Model home
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

The Desert Dome @ BNC Farms
Welcome to the Desert Dome! We are located in small village of Chaparral, NM. This is a great spot to get away from the hustle and bustle of life while still having all the city amenities close by. You can find lots of hiking and biking trails in the area. We love furry friends, and would be happy to have your pets here too. There is a fenced in back area for their use. All pets must be leashed if not in the fenced area.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.
Popular amenities for La Mesa holiday rentals
Other great holiday rentals in La Mesa

Stylish Casa | Mtn Views | Pet-Friendly | 5MinNMSU

Rustic SouthWest Retreat | 4BR| Desert Charm

Casa Majestica

360° Views, Spa, Billiards, Birdwatching, Private

Cozy 2 bedroom home in the heart of Picacho Hill

Modern, Mountainside Townhouse in West El Paso!

Sonoma Luxury Villa

Oasis Crosses | Movie Theater| 3BR
Destinations to explore
- Salt River Holiday rentals
- Tucson Holiday rentals
- El Paso Holiday rentals
- Albuquerque Holiday rentals
- Ruidoso Holiday rentals
- Ciudad Juárez Holiday rentals
- Santa Fe Holiday rentals
- Chihuahua Holiday rentals
- Lubbock Holiday rentals
- Nogales Holiday rentals
- Las Cruces Holiday rentals
- Pinetop-Lakeside Holiday rentals
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- Western Playland
- Sun Bowl Stadium
- New Mexico Farm & Ranch Heritage Museum
- El Paso Zoo
- El Paso Museum of Art
- El Paso Chihuahuas
- Southwest University Park
- Hueco Tanks State Historic Site
- La Rodadora Espacio Interactivo
- San Jacinto Plaza
- Parque Público Federal El Chamizal
- Dripping Springs Natural Area
- Farmers And Crafts Market of Las Cruces
- Sunland Park Racetrack & Casino




