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Hotels in Little Italy

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Top-rated hotels in Little Italy

Guests agree: these hotels are highly rated for location, cleanliness and more.

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Hotel room in Downtown San Diego
4.8 out of 5 average rating, 5 reviews

Downtown Living: Stylish 2BR Walk Anywhere

Stay in the heart of all the action and excitement. You're directly above the hottest nightclubs and restaurants (which can be noisy but we do provide earplugs ;) ) in the city in San Diego’s historic Gaslamp District in this updated 2-bedroom flat designed for comfort and convenience. Ideal for up to 5 guests with a king bed, queen bed and a twin air mattress. Enjoy fast WiFi, a 48″ Smart TV, AC, a stainless kitchen, hardwood floors, secure access, and walkable access to Gaslamp Quarter.

Superhost
An open living area features a large, dark sectional sofa and a modern dining table with four chairs. Natural light streams in through colorful stained glass windows, illuminating the hardwood floors and adding a vibrant touch to the space.
Hotel room in Downtown San Diego
4.87 out of 5 average rating, 107 reviews

Free Parking • Walk to Conv Center • 5 Beds •Loft

NOISE ALERT: As of May 31, 2024, a new restaurant and bar will open directly below this suite on the ground level of this building. In the evenings, music will play. Includes a workstation that allows you to work using a high-speed WiFi Internet Connection for your Zoom Meetings (Parking is included for 1 vehicle) We provide parking with 24-hour In/Out access for (1) vehicle in an enclosed parking structure that's (1) block away. You will check in first to receive our parking pass.

Superhost
A modern lobby area is presented with a combination of seating options, including inviting dark chairs and a spacious sofa. Soft lighting is enhances the space, with a large TV mounted on the wall and decorative plants positioned to add greenery.
Hotel room in Downtown San Diego
4.71 out of 5 average rating, 7 reviews

Stylish San Diego Downtown Marriott Suite

In the center of the action, Marriott Vacation Club, San Diego is a true escape that will greet you with a perfect blend of historic ambiance and contemporary design. Inspired by San Diego's renowned Gaslamp Quarter, many of the 264 well-appointed suites feature stunning San Diego views and atmospheric wood and metal finishes. Enjoy this sleek, sophisticated setting to unwind from a day of exploration and recharge before venturing out to experience San Diego's amazing nightlife

Hotel room in Downtown San Diego
4.67 out of 5 average rating, 130 reviews

Former 1924 YMCA, beautifully reimagined

The Guild Hotel offers 162 thoughtfully designed rooms and suites, including 12 lavish suites and a penthouse with a private rooftop. Each space blends modern comfort with luxurious touches, featuring bespoke furnishings like rose gold lighting and leather tufted headboards. Nostalgic design elements meet innovative, future-forward amenities for a truly refined stay. Enjoy a unique and calming retreat within this beautifully reimagined historic building.

The King Classic room features a spacious bed adorned with premium linens. A botanical wallpaper with muted tones creates a serene backdrop, while two bedside lamps provide gentle lighting. Dark curtains frame a large window, enhancing the modern design.
Hotel room in Little Italy
4.59 out of 5 average rating, 59 reviews

Modern King Room | Luxe Stay in Little Italy

Experience stylish comfort and modern design in San Diego’s vibrant Little Italy at Hotel Zindel. Perfect for couples, solo travelers, or business guests, our King Classic room is a private retreat with upgraded amenities and a prime location for an unforgettable visit. Highlights: → Spacious King Bed – Premium linens for restful nights. → Private Ensuite Bathroom – Modern and elegant. → Exclusive Amenities – Lounge, coffee bar, and shared desk.

A comfortable sleeping area features a Queen bed with a light-colored headboard. Floral wallpaper adds a vibrant touch to the room. Natural light enters through the glass doors leading to a private patio, which is lined with decorative railings.
Hotel room in Little Italy
4.58 out of 5 average rating, 12 reviews

Queen Studio in Central Little Italy (Patio)

Welcome to Little Italy Inn by Vantaggio Suites! Experience the perfect blend of comfort and convenience at our limited-service apart-hotel nestled in the vibrant heart of Little Italy. This studio (~220 sq ft) features a Queen bed + a patio and is located on the first floor of our apartment building. Enjoy walking distance access to restaurants, shops, the bi-weekly farmer's market (1/2 a block away), bars, nightlife, and more!

Superhost
Shared hotel room in Downtown San Diego
4.71 out of 5 average rating, 110 reviews

Stay Classy Hostel - Downtown - Solo Pod

Stay Classy Hostel is in downtown San Diego, just minutes from the Gaslamp Quarter, Petco Park, and the Convention Center—only 2 blocks from the Park & Market Trolley Station. We offer clean, modern, and affordable shared rooms with hotel-style comfort. Enjoy memory foam beds with privacy curtains, fast Wi-Fi, secure PIN entry, and stylish common areas. Perfect for travelers looking to relax, connect, and explore. Stay Classy.

Guest favourite
Hotel room in Downtown San Diego
4.9 out of 5 average rating, 115 reviews

2BR Top Floor Suite • Free Parking - Conv Center

FREE Parking + Walk to the Convention Center Stay in the heart of Downtown San Diego — just minutes from the San Diego Convention Center, Gaslamp Quarter dining, Petco Park, and the waterfront. The rare bonus? Free overnight parking is included for one vehicle. Whether you're visiting for a conference, business trip, or weekend getaway, this professionally managed boutique suite offers location, comfort, and simplicity.

The living area features a dining table paired with four turquoise stools. A console unit is positioned adjacent to the table, displaying decorative items. A wall-mounted television is visible above the console, and a round mirror adds a touch of elegance to the gray accent wall.
Hotel room in Downtown San Diego
4.76 out of 5 average rating, 130 reviews

Convention close by • 2BR Suite • Free Parking

FREE Parking + Walk to the Convention Center Stay in the heart of Downtown San Diego — just minutes from the San Diego Convention Center, Gaslamp Quarter dining, Petco Park, and the waterfront. The rare bonus? Free overnight parking is included. Whether you're visiting for a conference, business trip, or weekend getaway, this professionally managed boutique suite offers location, comfort, and simplicity.

Superhost
Hotel room in Downtown San Diego
4.8 out of 5 average rating, 41 reviews

Walkable Little Italy + Rooftop Dining. Free Bikes

Stay where the city comes alive—Hotel Republic San Diego puts you steps from Little Italy, 1 mile from the Gaslamp Quarter, and 2 miles from the bay. Grab free bikes, join rooftop yoga, or sip craft cocktails at Topside Terrace with epic skyline scenes. With on-site dining, upgraded Wi-Fi, pet-friendly rooms, and a modern coastal-chic vibe, it’s your perfect launchpad for adventure and connection.

Guest favourite
Hotel room in Downtown San Diego
4.8 out of 5 average rating, 20 reviews

Downtown San Diego Stay Near Gaslamp Quarter

PLEASE NOTE: The listing is specifically for a hotel room located within a hotel, distinguishing it from typical residential or apartment accommodations. Located in downtown San Diego, The Bristol Hotel offers comfortable rooms with two double beds and convenient access to nearby attractions like the Gaslamp Quarter and the San Diego Convention Center.

The Sofia Hotel
4.75 out of 5 average rating, 83 reviews

The Sofia Hotel

Unwind in a non-smoking room with a plush king bed, air conditioning, and modern amenities like a workspace, microwave, refrigerator, and cable TV. Special suites offer extra touches, including fine linens, ambient lighting, and elegant decor. Every detail blends Sofia signature charm with comfort and style, ensuring a memorable stay.

Popular amenities for Little Italy hotels

Quick stats about hotels in Little Italy

  • Total holiday rentals

    Explore 120 holiday rentals in Little Italy

  • Nightly prices starting at

    Little Italy holiday rentals start at £45 per night before taxes and fees

  • Verified guest reviews

    Over 1,540 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 80 rentals that welcome pets

  • Holiday rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

  • Wifi availability

    120 of Little Italy holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Little Italy rentals

  • 4.5 Average rating

    Little Italy stays receive an average rating of 4.5 out of 5 from guests

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