Holiday rentals in Murphysboro

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Top-rated holiday rentals in Murphysboro

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Cabin in Carbondale
4.99 out of 5 average rating, 104 reviews

Beautiful Cabin close to SIU/wineries/Shawnee

Beautiful cabin sitting in the middle of woods w/ a large entertaining deck that makes you feel like are " away from it all" even though you are 3 mins away from SIU! Features 4 bedrooms & 2 full baths with an open floor plan with plenty of room for family and friends! Enjoy the large deck to grill or to just enjoy a glass of wine from one of our local wineries. Large master suite with jacuzzi tub to unwind. Make use of the concrete party pad with firepit & bar/ game room. Location is perfect!

Top guest favourite
The exterior of a charming cottage features a welcoming entrance with a light-colored door. Two blue chairs and a small table are positioned on a stone path, surrounded by well-maintained grass and flower pots. In the background, horses can be seen grazing in a fenced pasture.
Guest house in Carbondale
5 out of 5 average rating, 289 reviews

Homestead Cottage

Enjoy tiny farmhouse life in this adorable 375 sq. foot cottage. Loaded with everything you need this little cottage is nestled privately behind some trees on our 11 acre farm. You will soon forget how close you are to town with the beautiful view from your windows and the pasture fence just steps out the back door. Whether you’re here for the wineries, amazing hiking, an SIU event (3 miles) or to visit with family, the Homestead Cottage will provide a comfortable retreat from any adventure.

Top guest favourite
A cabin with wooden exterior is surrounded by tall trees and shaded ground. A spacious porch is visible at the front entrance. A calm dog sits on the ground in the foreground, offering a glimpse of the natural tranquility of the setting.
Cabin in Alto Pass
4.99 out of 5 average rating, 316 reviews

Ma's Cabin, Alto Pass, IL. Fine country lodging.

Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award-winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10-mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs! No smoking in cabin!

Top guest favourite
Cabin in Pomona
4.96 out of 5 average rating, 237 reviews

Artist Vibe on the SI Wine Trail. New Kitchen!

What makes The Loft truly unique is its location. At the start of the S.I. Wine Trail, the cabin is just minutes to Cedar Lake, 15 minutes from nationally award winning BBQ, delicious ice cream, shopping, and fun of all sorts! On a 70 acre organic farm, the cabin is tucked into a breathtaking valley next to the Shawnee National Forest and has a gourmet kitchen and is filled with antiques, games & play space, original eclectic artwork, plus toddler gear so you can travel light! You’ll love it!

Top guest favourite
A spacious outdoor area is highlighted by a large swimming pool with inviting waters. Surrounding the pool, sun loungers provide ample relaxation space. The cabin features a wooden exterior and a large patio area, framed by vibrant trees and landscaping that showcases the beauty of the surroundings.
Home in Murphysboro
4.99 out of 5 average rating, 156 reviews

Embers of Murphysboro

Escape to the beauty of Embers of Murphysboro.  The sprawling landscapes and cabin with high end amenities have everything to offer for a weekend getaway or larger gathering.  Sucumb to the beauty of nature around you that will awaken your inner senses and relax your mind.  Nestled upon a  26 acre property the cabin will astound you with picturesque landscapes and a lodging infused with both character and luxury.  Explore local wineries, hiking trails, fishing,  boating , dining and more...

Top guest favourite
Cabin in Pomona
5 out of 5 average rating, 145 reviews

Modern Cabin at Trillium Ridge

Tucked into the rolling hills of the Shawnee National Forest, our modern cabin offers a welcoming retreat where comfort and nature meet. Wander down a private trail to explore or climb at the Holy Boulders, or take an easy drive to local wineries and see the iconic sights of Little Grand Canyon, Inspiration Point, and Pomona Natural Bridge. When you’re ready to slow down, return to soak in the hot tub, unwind in the sauna, and settle into our cabin made for rest and connection.

Top guest favourite
Flat in Murphysboro
4.9 out of 5 average rating, 73 reviews

The Windbreak

Forget your worries in this spacious apartment, the lower/first level of a 3-level house, a peaceful place at the woodsy end of a country lane, not far from two state parks, five lakes, wine trail, Southern Illinois University and other interesting features of this area. The 1st level apartment is large, has a kitchen, dining room, 2 bedrooms, living room/bedroom, a full bath, and a utility room, 2 exterior doors, one to a patio with a fire pit and charcoal cooker.

Guest favourite
Home in Makanda
4.83 out of 5 average rating, 126 reviews

Cedar Lake Retreat A

Enjoy a quiet, peaceful, pet-friendly retreat, less than a mile from Cedar Lake boat ramp/kayak launch and Poplar Camp Beach. This cute and comfy duplex is less than 6 miles from Giant City State Park, located in Shawnee National Forest, and just 4 miles from Southern Illinois University-Carbondale. Enjoy fishing, kayaking, and rock-climbing, or hit the Shawnee Wine Trails. If you’re a nature buff or you’re in town for SIU festivities, this is the place for you.

Top guest favourite
The treehouse is elevated on wooden stilts, surrounded by lush greenery. A wooden deck with a railing extends from the entrance, creating a welcoming outdoor space. Large windows brighten the upper level, while a sun art piece adorns the side of the structure.
Treehouse in Makanda
4.96 out of 5 average rating, 427 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Guest favourite
Home in Carbondale
4.86 out of 5 average rating, 309 reviews

Relaxing 3 Bedroom Cottage in Quiet Neighborhood

This happy 3 bedroom duplex will be a family favorite on your next trip to Southern Illinois. You'll enjoy 3 cozy bedrooms each equipped with a TV, 1 bathroom, ample deck space and firepit. We are located on a quiet street within walking distance of all Carbondale has to offer – Downtown Carbondale, restaurants and pubs (.8 miles), the Memorial Hospital of Carbondale (.5 miles), Carbondale Civic Center (.8 miles), Amtrak Station (.9 miles), and SIU (1.1 miles).

Guest favourite
The kitchen features wooden cabinetry and ample counter space, equipped with essential appliances including a dishwasher, microwave, and stove. A small dining table is visible, and an area rug adds warmth to the wooden flooring, complementing a neutral color scheme.
Apartment in Murphysboro
4.96 out of 5 average rating, 95 reviews

2 Bed 1.5 Bath Condo

We have a newly renovated 2 bedroom, 1.5 bath condo with WIFI located just 2 blocks off Walnut Street. Walking distance or just a short drive to many locally owned shops, restaurants, wine trails, lakes (both Kinkaid and Murphysboro lakes), SIU and breweries. Queen beds and TV's with Roku in both bedrooms. USB charging ports in both bedrooms.

Guest favourite
Flat in Carbondale
4.91 out of 5 average rating, 111 reviews

Modern Queen Suite Near SIU Carbondale

Stay in Suite 3 at Wall Street Suites, a modern queen suite near SIU Carbondale. This newly renovated micro-suite blends industrial charm with stylish urban design. Enjoy a full kitchen, Smart TV, queen bed & updated bath, plus a shared lobby workspace. Perfect for mid-term or monthly stays near SIU East Campus. Note: Access via stairwell.

Popular amenities for Murphysboro holiday rentals

Frequently Asked Questions

  • Are there family-friendly house rentals in Murphysboro?

    Murphysboro has more than 10 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in Murphysboro?

    Experience the best of Murphysboro with our house rentals, starting at about $80 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Murphysboro?

    Four-legged friends are welcome in Murphysboro. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in Murphysboro?

    Yes! Work meets play with ease at over 10 vacation rentals in Murphysboro featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Do house rentals in Murphysboro have air conditioning?

    Absolutely! We offer over 10 house rentals with air conditioning in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Murphysboro have a kitchen?

    Absolutely! We offer over 10 house rentals with a kitchen in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Murphysboro have wifi?

    Absolutely! We offer over 10 house rentals with wifi in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Murphysboro have free parking?

    Absolutely! We offer over 10 house rentals with free parking in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

Quick stats about holiday rentals in Murphysboro

  • Total holiday rentals

    Explore 30 holiday rentals in Murphysboro

  • Nightly prices starting at

    Murphysboro holiday rentals start at £22 per night before taxes and fees

  • Verified guest reviews

    Over 1,340 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    20 of Murphysboro holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Murphysboro rentals

  • 4.8 Average rating

    Murphysboro stays are highly rated by guests – averaging 4.8 out of 5!

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