Holiday rentals in Muscatine

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Top-rated holiday rentals in Muscatine

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 135 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Top guest favourite
Two horseback riders are positioned on a grassy hill overlooking a tranquil pond. The clear water reflects the surrounding greenery, enhancing the serene rural setting. The landscape features rolling hills, contributing to a peaceful country experience.
Farm stay in Riverside
4.92 out of 5 average rating, 356 reviews

Farm stay close to Iowa City, IA

15 min.-Iowa City, 5 min- Riverside Casino, & 35 min-Eastern Iowa Airport, Cedar Rapids, IA. Comfy beds, living room sectional pulls out to queen hide a bed, 32 acres of rolling hills, horseback riding (sm. fee)*, winter fun, & fishing pond. First 2 guests pay base price, then 3rd thru 10th guests pay an extra 30.00 EACH. NO PARTIES on our farm. We live on property in a separate home. Dogs welcomed (must be kenneled when you leave property)NOTE: NO OVEN in kitchenette. *contact for details.

Top guest favourite
The cottage's exterior features a welcoming facade adorned with colorful flowers and greenery. A spacious deck is bordered by stone pathways, while large windows allow natural light to flood the living spaces. Mature trees provide shade in the surrounding area.
Cottage in Le Claire
4.97 out of 5 average rating, 518 reviews

The Cottage. River views, event & dog friendly!

Make yourself at home in a fully renovated cottage built in 1910. This cottage sits on a steep hill above the original Homestead of Buffalo Bill Cody. Enjoy a beautiful Park directly behind you, full river views in front of you. BEFORE BOOKING PLEASE NOTE: *The cottage is on a steep hill. *You will hear trains. LeClaire is a river & train town. 🚂🌊 *This is a wooded property, There will be sticks, leaves and bugs. 🌿🐞 *There are MANY steps inside and outside, as it's built into a hill.

Top guest favourite
A modern cabin is set on a landscaped lot with a gravel path leading to the entrance. The structure features a mix of dark siding and wood accents, surrounded by open fields and distant tree lines, offering a serene rural setting.
Cabin in Princeton
4.96 out of 5 average rating, 135 reviews

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Favorited” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Guest favourite
A spacious home is visible with a combination of brick and siding exterior, featuring multiple gables and a large covered porch. A manicured lawn extends toward a serene pond, enhancing the natural surroundings. Clear blue skies contribute to the relaxing outdoor atmosphere.
Home in Morning Sun
4.91 out of 5 average rating, 245 reviews

Buckman's Guesthouse BnB (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Guest favourite
The exterior of a charming farmhouse is presented, featuring a white facade with a sloped roof. Lush green grass surrounds the front porch, which is shaded by large trees. A welcoming atmosphere is suggested by the open door and inviting entryway.
Home in Muscatine
4.97 out of 5 average rating, 115 reviews

Michelle's Place- The Farm House

Welcome to Michelle's Place- The Farm House. Where it's a farm feel, centrally located in town. It's a completely remodeled home with intentional planning and beautiful design for you to come rest at a home away from home. Close to parks, and walking trials while also only 4 minutes away from the historic downtown area! All aspects inside the home were uniquely picked by the host. With seasonal farm fresh varieties of berries, fruits, and vegetables to be enjoyed in your backyard!

Top guest favourite
The exterior of the Milk House features a red structure with gray siding, adorned with a triangular window and a decorative sun motif. A small porch with a welcome sign opens to a gravel path lined with flower planters. A chair and table are set for outdoor relaxation.
Farm stay in Iowa City
4.98 out of 5 average rating, 397 reviews

The Milk House at Lucky Star Farm

The Milk House is a unique space located in the countryside, between Iowa City and Kalona. This 700 square foot home has ample parking and room for four adults. The house is well appointed with a full kitchen, two luxurious queen beds, wifi and a Smart TV. Guests are invited to explore our 20-acre working farm with lots of livestock and two friendly dogs. It's a perfect blend of rural living with the perks of beautiful Iowa City 15 minutes away. Come unwind at Lucky Star Farm!

Top guest favourite
A view of the open-concept space highlights a kitchen area with a green countertop and a stove. The living area features light brown and tan upholstery on the seating, complemented by green carpet. A ceiling fan is visible along with warm lighting throughout the space.
Loft in Muscatine
4.95 out of 5 average rating, 238 reviews

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Top guest favourite
Home in Davenport
4.92 out of 5 average rating, 101 reviews

Rieder Ranch 4 bdrm 2 bath house

You'll feel right at home in my comfy midwest ranch. It's nestled into a friendly subdivision known for great Christmas lights & it's own 4th of July fireworks show! Backyard is fenced with large firepit, patio, and deck to enjoy throughout the seasons. Five minutes to I-80 and under 15 minutes to TBK Sports Complex, Eldridge IA, downtown Davenport, East Village, and Tax Slayer Center. This has been my home for 18 years, so it's got everything you need to feel at home!!

Top guest favourite
A serene view of the Mississippi River is framed by a large window. The soft orange hue of the sunset reflects on the water's surface. Silhouettes of two individuals can be seen walking along the riverbank, creating a peaceful scene.
Cottage in Moline
4.92 out of 5 average rating, 172 reviews

Stylish Riverfront Cottage in the Heart of the QC

This warm and unique cottage has a vintage meets modern theme. You will be just 50 ft off the Mississippi river! Enjoy panoramic river views in a vibrant area with great restaurants and coffee shops a short 2 min walk on the scenic QC River Way. You get the privacy of the ENTIRE home and so be noisy if you want-a 100watt stereo system is there for you to enjoy music & movies. Deluxe amenities ensure your comfort; outside has a 3-seasons room, deck, fire pit.

Guest favourite
A living room features a leather sofa, two vintage armchairs, and a round ottoman, creating a cozy seating arrangement. Natural light enters through large windows framed with sheer curtains. Dark wooden flooring contrasts with the light-colored walls and decorative art pieces are displayed throughout.
Home in Burlington
4.89 out of 5 average rating, 197 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Superhost
A serene riverside view is captured at sunset, highlighting calm waters and distant trees. A picnic table is positioned on a snow-covered area beside the river. The warm hues of the sunset reflect gently on the water, adding a peaceful ambiance to the scene.
Cottage in Rock Island
4.87 out of 5 average rating, 216 reviews

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

Popular amenities for Muscatine holiday rentals

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Quick stats about holiday rentals in Muscatine

  • Total holiday rentals

    Explore 20 holiday rentals in Muscatine

  • Nightly prices starting at

    Muscatine holiday rentals start at £52 per night before taxes and fees

  • Verified guest reviews

    Over 790 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 10 rentals that welcome pets

  • Wifi availability

    20 of Muscatine holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Muscatine rentals

  • 4.8 Average rating

    Muscatine stays are highly rated by guests – averaging 4.8 out of 5!

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