
Places to stay near Museum of Contemporary Art - Downtown
Book unique holiday rentals, homes and more on Airbnb
Top-rated holiday rentals near Museum of Contemporary Art - Downtown
Guests agree: these stays are highly rated for location, cleanliness and more.

Little Italy Historical
This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.
4.98 out of 5 average rating, 112 reviews
Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.
4.96 out of 5 average rating, 381 reviews
Artifact Inn - Historic Deluxe Studio in Downtown
The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.
4.89 out of 5 average rating, 108 reviews
Gorgeous 2Bd Corner Bungalow in Little Italy
Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.
4.93 out of 5 average rating, 408 reviews
Perfect Downtown Studio | Steps to Little Italy!
Conveniently located Downtown is this beautiful, light & airy studio apartment with everything you could need for a relaxing and comfortable stay. The studio features a free flowing design with a fully equipped kitchen, a beautiful queen bed, a workspace, a sparkling, modern bathroom and café style dining for two by the sunny window. Stay just steps to Little Italy with its mouth-watering restaurants, bakeries, piazzas & cafes or drive to San Diego’s best attractions just 10-15 mins away.
4.89 out of 5 average rating, 195 reviews
Beautiful Historic Home and Gardens Near Downtown!
Location, Location, Location...Welcome to Union Street Gardens. We are dedicated to providing a peaceful, serene atmosphere in which our guests can relax after a long day of exploring beautiful, sunny San Diego. This unique historic craftsman bungalow is just minutes from downtown, Balboa Park, the Zoo, beaches, and includes a Chef's kitchen, outdoor deck, gardens, fire pit and spa! Perfect for a family of 4 or two couples. Sorry no parties or large groups and no external guests please.
4.97 out of 5 average rating, 299 reviews
#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
4.9 out of 5 average rating, 761 reviews
Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.
4.95 out of 5 average rating, 163 reviews
Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
4.83 out of 5 average rating, 225 reviews
The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.
4.98 out of 5 average rating, 132 reviews
Downtown San Diego Loft | Best Walkable Location
Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.
4.94 out of 5 average rating, 515 reviews
Grand Victorian Manor • Luxury Downtown Stay
Welcome to The Jade Manor, a 126 year old Victorian reborn as a dreamy San Diego escape. Set inside a gated, Parisian inspired tropical oasis, this home blends historic charm with modern luxury. Sun soaked spaces, elegant details, and celebration ready vibes make it perfect for bachelorette weekends, birthdays, and unforgettable group stays, while still feeling refined, private, and welcoming for all travelers.
4.96 out of 5 average rating, 113 reviewsPopular amenities for holiday rentals near Museum of Contemporary Art - Downtown
Other top sights near Museum of Contemporary Art - Downtown
Apartment rentals with wifi

Dream Penthouse! The Most Amazing Bath & Views
4.98 out of 5 average rating, 219 reviews
Hilltop Harbor View- 2 Primary Suites-2 Balconies
4.92 out of 5 average rating, 193 reviews
NEW Stylish of Downtown Little Italy w Parking/AC
4.83 out of 5 average rating, 152 reviews
Bright and Trendy | Panoramic | Chic | Prime Locat
4.92 out of 5 average rating, 148 reviews
Charming studio close to convention center
4.8 out of 5 average rating, 339 reviews
Walk 2 Gaslamp & Petco; King bed, Parking/Patio!
4.94 out of 5 average rating, 447 reviews
Close to Airport Downtown Convention Center Petco
4.77 out of 5 average rating, 118 reviews
Modern Comfort in Uptown | A High-End Refuge
4.85 out of 5 average rating, 199 reviewsFamily-friendly house rentals

Designer Unit w/FirePit-Petco Park, Zoo, Downtown
4.97 out of 5 average rating, 118 reviews
Pool Oasis in Central Hillcrest by Park/Zoo
4.92 out of 5 average rating, 183 reviews
1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
4.94 out of 5 average rating, 102 reviews
Ventana Vista | Ocean View | EV Charger | Designer
4.97 out of 5 average rating, 286 reviews
Urban Greenhouse
4.99 out of 5 average rating, 204 reviews
Walk to Balboa Park and Hillcrest from an Immaculate Home
4.95 out of 5 average rating, 368 reviews
A Charming House. Short walk to Balboa park & Zoo!
4.88 out of 5 average rating, 294 reviews
Downtown View - 2 Story House Next to Little Italy
4.98 out of 5 average rating, 320 reviewsApartment rentals with air conditioning

Modern Bankers Hill Studio on Maple Canyon
4.84 out of 5 average rating, 162 reviews
Little Italy Penthouse -2 Sunset Balconies +Garage
4.9 out of 5 average rating, 112 reviews
Calm Luxury Penthouse Getaway With Panoramic Views
4.94 out of 5 average rating, 254 reviews
Designer Rental w/ FirePit- Petco Park, DT, + Zoo
4.99 out of 5 average rating, 139 reviews
Downtown Dream 3
4.86 out of 5 average rating, 137 reviews
Bright& Clean, Heart of Downtown Studio - Sleeps 4
4.86 out of 5 average rating, 281 reviews
Large Studio in Gaslamp, 3 bed w/ Parking included
4.87 out of 5 average rating, 120 reviews
Modern Elegance in Banker's Hill San Diego
4.81 out of 5 average rating, 135 reviewsOther great holiday rentals near Museum of Contemporary Art - Downtown

Contemporary Loft - Panoramic Harbor & City Views
4.97 out of 5 average rating, 129 reviews
Waterfront Little Italy Loft
4.89 out of 5 average rating, 102 reviews
Mountain View Retreat in Gated Estate (Hot Tub)
4.99 out of 5 average rating, 490 reviews
Vintage Spanish Revival Home - Balboa Park - Alcazar Court
4.97 out of 5 average rating, 448 reviews
Little Italy King Suite
4.97 out of 5 average rating, 99 reviews
4BR/5BD - Free Parking - Walk to Nightlife!
4.96 out of 5 average rating, 70 reviews
Upscale Remodeled 1B1B in Heart of Little Italy
4.94 out of 5 average rating, 17 reviews
Walk to Gaslamp & Petco • Rooftop Spa & Game Room
4.98 out of 5 average rating, 45 reviewsDestinations to explore
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Tijuana Beach
- Balboa Park
- San Diego State University
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Oceanside City Beach
- Las Olas Resort & Spa
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Oceanside Harbor





