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Apartment holiday rentals in Panamá Province

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panamá Province

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite
Flat in Panamá
4.93 out of 5 average rating, 155 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Superhost
A charming historic building features ornate white architecture with teal accents. Arched windows and balconies are visible on the upper levels, showcasing decorative wrought-iron railings. The entrance showcases double doors, inviting passersby to explore the structure's elegance.
Flat in Panamá
4.83 out of 5 average rating, 187 reviews

Best location - Unique and charming loft

Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Top guest favourite
Flat in Panamá
4.97 out of 5 average rating, 126 reviews

Apartment with a pool and unique views to remember

Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro. Restaurantes , 24 horas grocery store, y una vida nocturna genial. Casainos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Superhost
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Flat in Panamá
4.86 out of 5 average rating, 405 reviews

Designer Penthouse 16th Century Watchtower - Casco

Stay in one of Panama's most extraordinary homes—a three-story designer penthouse featuring the country's oldest surviving watchtower. Set atop one of Casco Viejo's oldest buildings, it offers breathtaking panoramic views, it's steps from the best restaurants, rooftop bars, cafés, boutiques, museums, and plazas. Whether you're exploring the city's rich history, celebrating with friends, working remotely, or enjoying a romantic getaway, it has the perfect balance of history, comfort and style.

Top guest favourite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Flat in Panama City
4.96 out of 5 average rating, 113 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top guest favourite
Flat in Panama City
4.98 out of 5 average rating, 123 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Top guest favourite
Flat in Panamá
4.93 out of 5 average rating, 46 reviews

Casco Antiguo Apartment with Balcony & Stone Wall

Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 194 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favourite
An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.
Flat in Panama City
4.93 out of 5 average rating, 127 reviews

Impressive ocean and Panama City views

Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Top guest favourite
Flat
5 out of 5 average rating, 27 reviews

Most Beautiful Loft in the Heart of Casco Viejo

Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Guest favourite
Flat in Panamá
4.98 out of 5 average rating, 156 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in Panama City
4.92 out of 5 average rating, 118 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of Casco Viejo, located on the third floor opposite one of Panama's most iconic squares, Plaza Catedral! Thanks to its privileged location, you'll enjoy a unique view of the square and the majestic Cathedral. Right in this lively square, you'll have a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Popular amenities for Panamá Province apartment rentals

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