
Family-friendly holiday rentals in San Marco
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in San Marco

Total holiday rentals
Explore 100 holiday rentals in San Marco

Nightly prices starting at
San Marco holiday rentals start at £52 per night before taxes and fees

Verified guest reviews
Over 6,020 verified reviews to help you choose

Pet-friendly holiday rentals
Find 70 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
60 properties have a dedicated workspace

Wifi availability
100 of San Marco holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across San Marco rentals

4.8 Average rating
San Marco stays are highly rated by guests – averaging 4.8 out of 5!
Top-rated family-friendly rentals in San Marco
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

Renovated home in Jacksonville near San Marco
Cozy, Convenient and Clean! Modern, 3 bedroom/2 bath home Near San Marco! Close to great shopping and restaurants, conveniently located a short distance from downtown, but just far enough away, great place to stay for downtown events. We provide Shampoo, conditioner, body wash, coffee, blow dryer, make up wipes, all the little things to make you feel right at home. Stream your favorite shows from every bedroom in the house. Washer and dryer included as well. 2.5 miles from Brooks Rehab Hospital
4.93 out of 5 average rating, 121 reviews
Serene Cottage in Walkable, Historic San Marco
This beautifully renovated cottage is a 5-min walk to local Hospitals and Clinics. San Marco Square is within walking distance w/ a theater, shops, & the best restaurants in town. The Southbank Riverwalk is blocks away & lovely for a sunset stroll. The elevated people mover is close by & handy for concert and stadium events. This home is perfect for professionals & health care visitors. Wonderful neighborhoods of Avondale & Riverside are just across the river. Centrally located for easy access.
4.99 out of 5 average rating, 227 reviews
San Marco Orange Blossom Cottage
Welcome to Orange Blossom Cottage! Beautifully appointed with all of the modern amenities that you might need. Full size stainless appliances, modern kitchen, high speed internet, Roku smart tv, cozy living room. Comfy queen bed, plenty of storage and a dedicated work space. Light and bright with a front porch and a private back patio. Enjoy a glass of wine or coffee, read a book and listen to the birds sing. Perfect for a weekend getaway or a longer stay if you prefer. Conveniently located!
4.89 out of 5 average rating, 130 reviews
Beautiful Retreat in the heart of San Marco
This charming, historic, all brick brightly lit home has been completely renovated with high end finishes and beautiful hardwood floors throughout. The open gourmet kitchen is fully equipped with stainless appliances and plenty of amenities. Master bedroom has en-suite bath with adjoining laundry room. Relax in the screened-in porch. Amazing location within walking distance to St. John's river, restaurants & shops in San Marco square, and major hospitals. Everbank Stadium is 2 miles away.
4.97 out of 5 average rating, 192 reviews
San Marco Suite (2nd Floor) - a Hip Historic Space
Comfy for corporate travelers, short visits, extended stays & family friendly. Located within blocks to restaurants, shops, downtown Jacksonville, the sports and entertainment districts, and minutes to hospitals! This is a comfy, clean, and stylish second floor (2nd floor) apartment with 2 bedrooms plus 1 full bathroom to comfortably accommodate 6 guests when utilizing the sleeper sofa. Close proximity to Jax Water Taxi. Please view our other listings at this address by opening my profile.
4.86 out of 5 average rating, 151 reviews
Renovated 2BR w/Porch & Pool Table • San Marco
Just 2 Blocks to the River, Dining & Shopping! Welcome to your beautifully renovated upstairs duplex unit in the heart of charming San Marco. Enjoy a fully stocked kitchen, spacious screened porch, dedicated office space, arcade, pool table, bikes, beach chairs, and fast WiFi, for work or play. Soak in the neighborhood’s historic charm, stunning sunsets, and walkable streets. With local dining and boutique shopping just steps away, this bright and cozy space is ready to welcome you!
4.97 out of 5 average rating, 101 reviews
San Marco Home • Pool, Hot Tub, Grill
Welcome to your Jacksonville getaway! This stylish 3-bedroom, 2-bath home in the heart of San Marco is just 10 minutes from Jaguars Stadium and close to vibrant cafes, parks, and boutiques. Ideal for families, couples, groups, or long-term stays, this home combines comfort, charm, and resort-style amenities. Pool Heating: $100 per stay for short visits (≤4 nights). For longer stays or winter months: $50 setup + $12/night, or $200 flat. Please request at least 48 hours in advance.
4.81 out of 5 average rating, 154 reviews
Retro Bungalow
Our 1,100 ft.² was renovated in 2023 with new central heat and air, ceramic tile and hard wood flooring, kitchen appliances and cabinets, bathrooms, and electrical and plumbing. Multiple windows in every room let in tons of natural light. Due to owner allergies, we do not allow pets or companion animals. The home is only a block away from 8 restaurants and local shops. We allow a maximum of 4 overnight guests and 4 visitors on the property at one time.
4.99 out of 5 average rating, 106 reviews
Luxury Designer San Marco Oasis-Sleeps 6
Welcome home to your home away from home! 2 bedrooms/ Sleeps 6, 9 min. to the Stadium, 5 min. to Baptist/Wolfson Children's/MD Anderson hospital, 8 min to Memorial Hospital, 9 min to St. Vincent's hospital, 3 min to San Marco Square, 24 min to Jax Beaches. This designer home with spacious high ceilings is stocked with all details including a Ninja blender, Air fryer and Insta pot. Enjoying relaxing in the Gazebo in the peaceful backyard and grilling out.
4.93 out of 5 average rating, 143 reviews
*Heated Pool, Hot Tub & Grill Retreat • Free Wi-Fi
Welcome to your private Jacksonville oasis — a relaxing, well-equipped home featuring a heated pool, hot tub, and outdoor grill, perfect for families, couples, or small groups looking to unwind in comfort. Whether you’re here for a getaway, work trip, or visiting loved ones, this home offers the space, amenities, and privacy you need for a great stay. Pool heating available for $100/night with 48h notice. Hot tub heating is complimentary.
4.81 out of 5 average rating, 189 reviews
The Riverside Studio | San Marco
Private standalone studio in San Marco with your own entrance, gated courtyard, and dedicated parking. Walk to the river, San Marco Square, restaurants, and shops. Full kitchen, in-unit laundry, fast Wi-Fi, and a 55-inch smart TV. Just 3 minutes from Baptist Hospital and MD Anderson. 5 minutes to EverBank Stadium. A real home base whether you're in town for work, treatment, a Jags game, or just exploring Jacksonville.
4.98 out of 5 average rating, 158 reviews
San Marco Chic Home 2 blocks from San Marco Square
Welcome to our beautiful newly, fully renovated San Marco Villa. This home is the perfect balance of a historic feel with a modern, chic vibes. Enjoy all the comforts of your own home right at your fingertips. This residence is perfect for couples, solo adventurers, business travelers, and families! This home is only a few steps away from adorable San Marco Square - teeming with restaurants, bars, and boutiques!
4.92 out of 5 average rating, 104 reviewsPopular amenities for San Marco family-friendly rentals
Family-friendly home rentals with a hot tub

Gorgeous Florida Pool and Spa Home
4.85 out of 5 average rating, 111 reviews
Private FL Home with Pool, Hot tub & Luxury Master
4.88 out of 5 average rating, 246 reviews
~Billiard Abode_Sleeps 12_Heated Pool & Spa~
4.81 out of 5 average rating, 151 reviews
Pool & Hot Tub Home w/ Game Room! 1 Mile to Beach!
4.88 out of 5 average rating, 121 reviews
Seaside Paradise - Pool! Spa! Game Room! 12 Beds!
4.87 out of 5 average rating, 107 reviews
The confetti house - 1 mile from the Mayo clinic!
4.96 out of 5 average rating, 223 reviews
Private suite w Jacuzzi/Pool/Porch JAX safest Area
4.89 out of 5 average rating, 101 reviews
Paradise Palms Estate
4.91 out of 5 average rating, 182 reviewsFamily- and pet-friendly home rentals

The 1910 General Store - residence
4.97 out of 5 average rating, 673 reviews
Chill Retreat w/ Private Yard • Near Downtown
4.9 out of 5 average rating, 280 reviews
Spacious 2/1 in historic neighborhood- NO parties
4.96 out of 5 average rating, 154 reviews
Spacious Centrally-Located Historic Home
4.95 out of 5 average rating, 153 reviews
2 BR Historic Springfield Apt
4.98 out of 5 average rating, 143 reviews
*Historic Dream *Walkable *1 mile to Downtown Jax
4.97 out of 5 average rating, 163 reviews
Riverside! Enjoy 5 points & King St. U'LL LOVE IT!
4.82 out of 5 average rating, 251 reviews
Jacksonville 2-BR Bungalow | Sauna & Dog-Friendly
4.96 out of 5 average rating, 112 reviewsFamily-friendly home rentals with a pool

Private Bungalow with Pool/55” tv
4.91 out of 5 average rating, 415 reviews
Historic Avondale Pool House | Guest Favorite
4.92 out of 5 average rating, 428 reviews
Avondale Retreat - Private Home with Heated Pool
4.99 out of 5 average rating, 198 reviews
Retreat on the river
4.89 out of 5 average rating, 403 reviews
Elegant & Stylish Pool House with Arcade!
4.87 out of 5 average rating, 118 reviews
Serenity and Amazing Views - Home on River w/ Pool
4.9 out of 5 average rating, 325 reviews
Sunset near the Lake/12guests/4bdrs/2baths
4.94 out of 5 average rating, 266 reviews
Cozy Home with Heated Private Pool and Patio
4.92 out of 5 average rating, 169 reviewsDestinations to explore
- EverBank Stadium
- St Augustine Amphitheatre
- University of North Florida
- VyStar Veterans Memorial Arena
- St Johns Town Center
- Kathryn Abbey Hanna Park
- Lightner Museum
- TPC Sawgrass
- Fort Clinch State Park
- Vilano Beach Fishing Pier
- Fountain of Youth Archaeological Park
- Okefenokee Swamp
- Summer Haven st. Augustine FL
- Huguenot Memorial Park
- Adventure Landing Jacksonville Beach
- Flagler College
- Memorial Park
- Crescent Beach
- Little Talbot
- Ravine Gardens State Park
- St. Augustine Alligator Farm Zoological Park
- Catty Shack Ranch Wildlife Sanctuary
- Kingsley Plantation
- Anastasia State Park





