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Holiday rentals in Santa Maria

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Maria

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Apartment in Mercedes
4.94 out of 5 average rating, 145 reviews

Quiet huge 4 bed condo 2 miles by the Outlets!

Centrally located in the Rio Grande Valley. This quiet 3 bedroom condominium is a shoppers paradise only two miles away from the Mercedes Outlets! Travel into the most tourist friendly border city in Mexico, the city of Progreso, only 10 miles away! Head to the beach at South Padre Island, about 50 miles away. Be mesmerized by Elon's Space X at Boca Chica Beach 67 miles away! Level 2 charging outlet (nema 14-50R) reserved for you, bring your own EV charger. Unlimited free parking on premises.

Top guest favourite
A spacious outdoor deck features wooden furniture, including a dining table with several chairs, offering views of the serene lake. The area is surrounded by lush greenery, with a hammock and a decorative trellis visible, enhancing the connection to nature.
Guest house in McAllen
4.97 out of 5 average rating, 299 reviews

Rm 101 Ethereal @ PeculiarNest Lake Conception

A beautiful lakefront one-bedroom cabin overlooking a 7-acre private lake and situated inside a one acre permaculture food forest/garden. It is a haven for birders and naturalists as well as the wildlife we share the space with. Enjoy feeding the roaming peacocks, viewing the sunrise and sunset, and sipping coffee on the private porch or pier. Additional units (apartment style&private rooms) are available to meet our guests' varying needs. Please check out my other listings in the profile.

Top guest favourite
Apartment in Weslaco
4.98 out of 5 average rating, 103 reviews

New Luxury Condo in Weslaco

Your family will be close to everything when you stay at this Condo located in the middle of the Rio Grande Valley with Interstate 2 / US 83 only 2 blocks away. Located within minutes from the Rio Grande Valley Premium Outlets, Ross, HEB, Walmart, Home Depot, McDonald's, Burger King, Jack in the Box, gas station and you can walk to the Dollar General store. You will be 15 minutes away from the Mexico border. This is a quiet family gated community, you will have 2 parking spots on the property.

Top guest favourite
Home in Edinburg
4.99 out of 5 average rating, 105 reviews

The Serene Home

Welcome to our Serene Home, where tranquility meets luxury for the ultimate escape. Nestled in the heart of Edinburg, this vacation home is a haven for those seeking a peaceful and rejuvenating gateway. The design blends Japanese with elements of zen-inspired architecture, creating a harmonious space that fosters relaxation. Natural light floods through large windows, illuminating the open living spaces. Embrace the serenity, and create lasting memories in this peaceful vacation home.

Guest favourite
A shared outdoor pool area is surrounded by a wooden deck and is complemented by a cabana featuring a green wall and decorative signage. Potted plants are positioned near the edge of the pool, providing a refreshing touch to the space.
Apartment in Mercedes
4.81 out of 5 average rating, 171 reviews

Cozy and cute condo 3-5 to outlets n Stockshow

This unique place has a style all its own. Enjoy your gateway in this fully stocked closed to everything! You will have access to a huge pool and an assigned private pergola with tv and fire pit! Condo is completely private with private entrance Backyard pool area is shared only with two other Airbnb units Perfectly located in the heart of the valley: 🛍 Just 3 minutes to the outlet mall 🌆 25 minutes to McAllen 🚗 15 minutes to Harlingen 🏖 50 minutes to South Padre Island

Top guest favourite
A single-story home featuring a brick façade and a manicured front yard. Two palm trees stand nearby, while a concrete driveway accommodates multiple vehicles. Windows are framed by greenery, creating a welcoming exterior view under a partly cloudy sky.
Home in Weslaco
4.94 out of 5 average rating, 154 reviews

My House

Mi Casa Tu Casa Weslaco Tx, a small city that has everything. Enjoy every moment in this home that is made especially for you!.. 16 Minutes to Progreso bridge (Progreso México) 16 Minutes to Donna bridge (México Rio bravo) 31 Minutes to Valley International Airport (Harlingen tx) 23 Minutes to Mcallen International Airport and Plaza Mall 13 Minutes to Rio grande Valley Premium Outlet 6 Min from 83 Hwy 1:12 Min to south Padre island via 1-2

Guest favourite
A charming guesthouse exterior is framed by a neat garden bed featuring potted plants and decorative stones. The well-maintained pathway leads to a welcoming door, complemented by two windows that allow natural light to fill the interior spaces.
Guest house in Harlingen
4.84 out of 5 average rating, 210 reviews

Harlingen Guesthouse with a Pool

This place is a guesthouse located at the outskirts of Harlingen Texas. Very peaceful being it is out of city limits but still very close to restaurants, shopping etc. Just a 4 minute drive. You will have access to the pool and outdoor furniture as well as a charcoal grill. It is also a 45 minute drive to South Padre Island and 35 minute drive to the big city of Mcallen, Tx. and 15 minutes away from the outlets in Mercedes Tx.

Top guest favourite
The kitchen showcases wooden cabinetry and modern appliances, including a stainless steel refrigerator and oven. A small table with two chairs is positioned near the entrance. The space features tile flooring with a tiered step leading to the living area.
Guest house in Harlingen
4.99 out of 5 average rating, 106 reviews

Peaceful Country Getaway

This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes

Top guest favourite
A spacious living room is presented with a light-colored sofa facing a flat-screen TV mounted on a wooden console. Two green accent chairs flank a glass coffee table, while a ceiling fan provides airflow. Natural light filters through wood shutters, creating a relaxed environment.
Home in Harlingen
4.99 out of 5 average rating, 96 reviews

Private Fenced Yard | Near Dining & Shopping

Welcome to Casa by CMC I Enjoy a spacious living room with reclining green sofa chairs, a relaxing patio, and backyard. Each bedroom includes a TV, plus a 1-car garage and washer/dryer for convenience. Located 5 minutes from restaurants, 10 minutes from the medical center, and a short drive to Weslaco, McAllen/Edinburg, Brownsville, and South Padre Island—your perfect home away from home.

Guest favourite
A spacious living area features a dark leather sectional sofa, paired with a sleek black recliner. Natural light fills the room through three windows, while a central coffee table stands between the seating. Decorative plants and modern light fixtures add a contemporary touch.
Flat in Weslaco
4.92 out of 5 average rating, 136 reviews

Modern comfortable retreat in gated community!

Minutes away from the outlet mall, the Progreso International bridge & much more. Perfectly located in the mid valley so you can decide if you want a beach day or a shopping day!! We welcome long term guests, medical visits, corporate visits etc. We want you to feel as comfortable as possible while you stay with us! Enjoy the best AirBNB experience available!

Guest favourite
Flat in Harlingen
4.93 out of 5 average rating, 106 reviews

Fresh, Modern + Convenient Apartment

Indulge in the serenity of this exceptional apartment nestled in Harlingen, one of the Rio Grande Valley’s burgeoning locales. Whether you’re seeking a relaxing vacation close to numerous amenities or traveling for business with convenience in mind, this impeccably clean home offers the perfect retreat for any purpose.

Guest favourite
Home in Mercedes
4.91 out of 5 average rating, 57 reviews

Sleeps 10 | Game Room + Pool Table | Truck Parking

Restful and apacious 3BR/2BA home in Mercedes, TX — sleeps 10 for less than two hotel rooms. Built for families, work crews, nurses, and road-trippers exploring the Rio Grande Valley. Base rate covers up to 4 guests. Additional guests just $12/night — still a fraction of booking multiple hotel rooms.

Popular amenities for Santa Maria holiday rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Cameron County
  5. Santa Maria