House holiday rentals in Simpsonville

Find and book unique houses on Airbnb

Top-rated house rentals in Simpsonville

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
A screened porch is highlighted, featuring comfortable wooden seating with light cushions and a matching table. Natural light is allowed through large windows and a skylight, providing a view of the surrounding greenery. A small potted plant decorates the table, enhancing the relaxing atmosphere.
Home in Greenville
4.96 out of 5 average rating, 135 reviews

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Top guest favourite
A serene bedroom is highlighted by a four-poster bed adorned with decorative pillows and a soft blanket draped at the foot. Natural light filters through the sheer curtains on the left, while a gold-toned coffee table sits in front of the bed, providing a modern touch.
Home in West End
4.91 out of 5 average rating, 150 reviews

Best Nest Loft-3Beds-1 Block fr Main/Walk Downtown

Enjoy the fun of GVL downtown! Walk the illuminated Main St. Trolley, bike, walk to eateries-breweries-shops-Falls/bridge-trails-theaters/venues & fun. Singles, couples-co-workers-friends-art/music lovers +. Entire 2nd floor. Newly renovated spacious historic loft- 9' ceiling-wood floors-lg glass shower. Relax on private balcony,cook in large kitchen, fast wifi/desk & record player.1300 sq ft.3 beds & luxe bath. SMART TV.Less busy area 1/2 block fr Main St.Sleeps 4.AGES 12+ per safety info

Guest favourite
The living room features a green sectional sofa arranged around a round wooden coffee table. A textured area rug anchors the seating area. A desk with a lamp and chair is positioned against the wall, complemented by decorative plants and wall art.
Home in Greenville
4.92 out of 5 average rating, 105 reviews

Pet-Friendly 2BR • Fenced Yard Near Downtown GVL

Located in Greenville’s Historic Dunean District, this cozy 2BR home is less than 10 minutes to Downtown Greenville, Unity Park, Falls Park, and the Swamp Rabbit Trail. Enjoy a pet-friendly stay with a fully fenced backyard, enclosed sunroom with hammock, garden views, and high-speed fiber WiFi. This is an allergy-friendly, fragrance-free home using only non-toxic cleaning and laundry products—no scented candles or air fresheners. Nestled in a quiet, safe neighborhood close to restaurants.

Superhost
A contemporary living area features a comfortable gray sofa with accent pillows, positioned beside a coffee table. A flat-screen TV is mounted on a shiplap wall above an electric fireplace. Natural light floods the space through window coverings, illuminating the stylish decor.
Home in Simpsonville
4.96 out of 5 average rating, 131 reviews

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Top guest favourite
A bright living room features two leather sofas positioned around a cozy area rug. Large windows provide ample natural light, with a mounted TV above a wooden mantel. Decorative wall frames add character to the space, complemented by a soft throw draped over one of the sofas.
Home in Simpsonville
4.95 out of 5 average rating, 155 reviews

Simpsonville Southern Comfort

Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Guest favourite
A spacious living room features a large sectional sofa adorned with various pillows. A stylish floor lamp stands next to the sofa, while a coffee table with decorative items sits nearby. A potted plant adds a touch of greenery, and light streams in through a window with soft curtains.
Home in Greenville
4.95 out of 5 average rating, 155 reviews

Stylish 3BR Home: Pet-Friendly, Outdoor Lounge

Welcome to Chardonnay Chateau, a stylish 3 bedroom, 2 bathroom home just 3 miles from Downtown Greenville. We are conveniently located next to: Shops at Cherrydale (0.7 mi) Downtown Greenville (3.5 mi) Bon Secours Wellness Arena (3.5 mi) Downtown Traveler's Rest (7 mi) Our home provides ample space to enjoy with your loved ones, including a converted carport that is now used as a place to rest and rejuvenate in the outdoors. We can’t wait to welcome you into our home!

Guest favourite
A bright living room features a comfortable gray sofa, patterned accent chairs, and a glass coffee table. Large windows allow natural light to fill the space. In the outdoor area, a playground with a slide and climbing structure is visible within a fenced yard, perfect for children.
Home in Simpsonville
4.9 out of 5 average rating, 113 reviews

Updated 4 BR Family Friendly Escape w/ Swingset

>>Experienced SuperHosts!<< This stylishly updated home is conveniently located just 3 minutes from the shopping & dining in Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house is perfect for families, groups of friends, and workers on assignment in the area! Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs.

Top guest favourite
A calming bedroom features a spacious bed with crisp white linens and decorative pillows. A ceiling fan enhances airflow, while a large TV is mounted on the wall. A potted plant adds a touch of greenery, and soft light is provided by bedside lamps.
Home in Greenville
4.99 out of 5 average rating, 146 reviews

Family & Pet Friendly Home - Sleeps 8

Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Top guest favourite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 235 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Superhost
A welcoming porch is depicted, featuring a comfortable seating area with a light-colored sofa and decorative pillows. Sheer curtains provide a gentle separation from the outdoor view. A natural fiber rug lies on the patterned floor, contributing to a cozy atmosphere.
Home in Greenville
4.89 out of 5 average rating, 101 reviews

Historic Mill House

Located only 5 minutes from Downtown, this Little Old Mill House is a perfect place to stay! You will be close to many local coffee shops and cafes. The Swamp Rabbit Trail, Downtown, and Unity Park are just a short bike ride away. Our updated Mill House holds a lot of beautiful history and is filled with antiques and art from local artists. The yard doesn’t have a lot of privacy (transitional neighbourhood). NO PETS.

Top guest favourite
A welcoming living area is displayed, featuring a comfortable sofa and a matching armchair. A wooden coffee table sits in the center, surrounded by a decorative area rug. A flat-screen TV is positioned on a wooden console against the wall, and natural light filters in through nearby windows.
Home in Simpsonville
4.96 out of 5 average rating, 181 reviews

Water Oak Retreat / Comfy king bed, big back yard!

-Private deck with grill and eating area - Fully stocked kitchen with tea, coffee, basic cooking needs and snacks -Safe and quiet neighborhood -1 mile from all of downtown Simpsonville's shops and restaurants -1 mile to huge park with playground, tennis, pickleball, basketball, walking trail, and farmers market -Short 20 minute drive to downtown Greenville -Perfect for families and those traveling for work

Top guest favourite
Home in Fountain Inn
4.97 out of 5 average rating, 119 reviews

Spacious 3 BR house with private backyard.

Welcome to our peaceful retreat! Nestled in a quiet corner, our cozy Airbnb features a charming fire pit for evening relaxation, a screened-in porch perfect for sipping your morning coffee or unwinding in the evening, and a fenced-in backyard for added privacy and comfort. Plus, enjoy the fun of our pool during warm weather. We hope you enjoy a tranquil stay filled with warmth and relaxation.

Popular amenities for house rentals in Simpsonville

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Quick stats about house rentals in Simpsonville

  • Total holiday rentals

    Explore 70 holiday rentals in Simpsonville

  • Nightly prices starting at

    Simpsonville holiday rentals start at £22 per night before taxes and fees

  • Verified guest reviews

    Over 2,180 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wifi availability

    70 of Simpsonville holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Simpsonville rentals

  • 4.8 Average rating

    Simpsonville stays are highly rated by guests – averaging 4.8 out of 5!