Holiday rentals in Edisto Island

4.92 out of 5 average rating, 209 reviews

Tranquility

Tranquility lives up to its name. Peace & quiet are the words guests use most to describe their visit. Less than 4 miles from the beach & 1 mile from the boat landing and hiking/bike trails, this is the place to unplug & reconnect with family & friends. To make sure you have a great vacation and know what to expect during your stay, it is important to read ALL information in our listing carefully. In addition to NOT being on the beach, several features make our home unique and not for everyone.

4.98 out of 5 average rating, 127 reviews

The Edisto Escape Getaway ~ Sleeps 8~ 75" TV

Thank you for considering The Edisto Escape for your next adventure! Our cozy 3bdrm, 2bath retreat sleeps 8 guests, with queen beds in each room ensuring a restful night's sleep. Enjoy entertainment on our 75-inch TV for cozy movie nights in. Located just a short 5-minute drive from the nearest beach access, our property offers convenience, comfort, and privacy. Please read the entire listing before booking. While linens, towels,& toiletries are not provided, alternative options are available.

5 out of 5 average rating, 18 reviews

Pompano Pool House

Newly Refreshed for 2025 Quiet Street w/Pool, Dog Friendly Discover authentic rest and relaxation that can only be found during an amazing vacation at Pompano Pool House. This well maintained home is tucked away on quiet Pompano Street. While the setting is private, everything Edisto Beach has to offer is at your fingertips. Restaurants and shops are blocks away. The beach is just a leisurely stroll around the corner. Sit back and relax on the screened porch overlooking the large private pool.

4.98 out of 5 average rating, 101 reviews

Guest house in Hollywood

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Welcome to the farm! This cute little farm studio is ready for your enjoyment! With a horse front view and rows of flowers in sight, you will be sure to soak in all the feels of farm life all while being close to West Ashley, 30 minutes from Down Town Charlestion and 35 min from beach access. Tucked in behind the hustle and bustle of city life you can put your feet up and relax, walk the gardens or check out the cute farm animals. Truly this is a unique stay that you don't want to miss!

4.97 out of 5 average rating, 115 reviews

Marshfront Villa In The Trees - Near Beach & Bay

"The most unique and relaxing place to enjoy the tranquility and experience of Edisto. We did not want to leave" - Sambo Nestled atop 360-degree marsh views, you'll be immersed in the exotic natural beauty and wildlife of the Edisto sea island. Hear the waves crashing at the beach from the front porch and watch the marsh tides rise and fall from your choice of the many porches. "Nature with luxury.. our group loved floating from the house out to the inlet for private beach days" - JP

4.94 out of 5 average rating, 120 reviews

Serene Edisto Beach Cottage Among Stately Oaks

Enjoy the island breezes on one of two screened in porches under beautiful oak trees. Located on the 5th fairway at Wyndham Resort. This three bedroom home with its open lofty living area and spacious master suite is the perfect family retreat. Wyndham offers amenities including three swimming pools, beach cabana with restrooms, tennis, gym and putt putt. Availability is not guaranteed. Please check with resort for pricing and availability. Home is wheel chair accessible including a ramp.

Cottage in Saint Helena Island

5 out of 5 average rating, 246 reviews

Harbor River Cottage

Romantic cottage on three-acres surrounded by gorgeous South Carolina waterways with endless views on all sides! Cottage is dog-friendly, has a fully-fenced front yard and screened-in porch. Full kitchen, private parking, washer & dryer, 55" TV with DirecTV. A short 10 minute drive from Hunting Island State Park, and 20 minutes to Downtown Beaufort and all the major attractions. Cottage is beautifully furnished with custom pieces to make this your ultimate low country luxury getaway!

5 out of 5 average rating, 147 reviews

Cottage in Beaufort

Private cottage in the pines

This cottage has a unique combination of being close to everything, while still maintaining a very private feel. The cottage is accessible by its private, dedicated drive. This new guest cottage has a King sized bed, as well as a pullout xl twin. The home boasts a large screen tv viewable from every angle, a full sized bath, full kitchen, exquisite outdoor shower, fire pit, full laundry, and all the amenities of home. 10 minutes to Beaufort/Parris isl. Boat parking available on site.

5 out of 5 average rating, 39 reviews

Cottage in Edisto Island

Cozy cottage in ACE Basin mins from Edisto Beach

If you want to scroll through your phone and stay plugged in….The Creek House is NOT the place for you (we have wifi)!!! If you are looking for solitude, downtime, a recharge from the grind, to watch the sun set, enjoy history and Mother Nature..then please come visit!!! The Creek House is in the heart of ACE Basin, on Bailey Creek, overlooking the South Edisto River. Build a campfire, get cozy in the cottage, view roseate spoonbills, and catch fish!! Property is under surveillance

4.98 out of 5 average rating, 111 reviews

Lovely Edisto Beach home/a short walk to the beach

Otter Escape is perfectly located on a quiet cul-de-sac only 450 steps from the beach. Our home is spacious inside and out. Main floor master has a king bed, master bath with shower and soaking tub. Two upstairs bedrooms, each with a queen size bed, a private bath and a TV in each bedroom. Open space living and dining area join a fully stocked kitchen that leaves nothing to be desired. Enjoy the lulling sounds of the ocean while deer watching on both the front and back decks.

Apartment in Edisto Island

4.89 out of 5 average rating, 180 reviews

A Room With a View. Recently Renovated Condo!

If you are looking for a comfortable, easy to access, quiet getaway, then you have found it. This pristine, recently refurbished studio condo has everything you need. Huge 12x12 deck offer additional outdoor space for relaxing. On the 9th green of the Plantation Course. Short walk or bike ride to the beach. You will love the location and the space. Very close to The Waters Edge coffee shop, Ella & Ollies, bike rentals. Sister property to All Inn on Edisto and Cozy Edisto Condo.