Hotels in Key West

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Top-rated hotels in Key West

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Guest favourite
Hotel room in Key West
4.85 out of 5 average rating, 690 reviews

The Sanchez House Room #2

There is no better welcome to Key West than staying in local and famous folk artist Mario Sanchez's birth home. This home was built in the 1860's in the heart of the historic Gato and Merrero cigar factory villages. Featuring original Dade County pine construction, and located right on historic Duval Street, the Sanchez House is guaranteed to offer the historic atmosphere and living a part of Key West many visitors want to experience. Sit on the balcony and enjoy the trade winds & Ocean Breeze.

Guest favourite
A bright bedroom features a spacious bed against a floral wallpaper backdrop, complemented by colorful decorative pillows. A bedside table with a vintage lamp adds character, while a door opens to a charming balcony area. Natural light fills the room, highlighting the warm wood flooring.
Hotel room in Key West
5 out of 5 average rating, 56 reviews

Marrero's Guest Mansion Adult Only (21+) Room 7

Adult Only (21+) Boutique Hotel. Experience the grandeur of the stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. Located in the heart of Old Town, just half a block from Duval Street. This second floor room has a long and distinctly resonant history thanks to the benevolent touch of Enriquetta Marrero, the former wife of the mansion's original owner. Mrs. Marrero's favorite room includes a pillow top king bed, private bath, sitting area, and balcony.

Guest favourite
Hotel room in Key West
5 out of 5 average rating, 7 reviews

Steps to Duval St + Free Breakfast, Pool & Spa

Located at the quiet end of Duval Street, The Guesthouses at Southernmost Beach Resort offer an adult-focused sanctuary with a sophisticated Key West vibe. Guests enjoy "stay at one, play at all" access to the entire resort, including 3 pools, a private beach, and oceanfront bars. Walk to the Southernmost Point or relax in lush tropical gardens. Highlights include the beach-chic decor, world-class spa, and daily breakfast, blending boutique intimacy with full-scale luxury amenities.

Guest favourite
A well-lit bedroom features a spacious bed with a light-colored quilt, complemented by two bedside tables with orange lamps. French doors open to a balcony overlooking lush greenery. A light blue wall adds a calm touch, while a white wicker chair is positioned near the window.
Hotel room in Key West
5 out of 5 average rating, 20 reviews

Aquamarine Deluxe King

***21 and up*** Enjoy this charming hotel located 2 blocks from the Historic Wharf and 4 blocks to Duval St. This room is just steps away from our main pool, and appointed with a king bed with a walk in shower, Keurig coffee maker, TV, patio, and mini fridge. Perfect romantic getaway for 2! It shares a small patio with the neighboring room. Our property sports 2 pools, lush gardens, sitting areas, complimentary breakfast, and all the amenities you would need to enjoy Key West!

The resort’s exterior is presented with white wooden siding and a classic rooftop structure. Palm trees frame the view, emphasizing the tropical environment. Expansive balconies with white railings offer a welcoming aesthetic, while large windows allow natural light to illuminate the interior.
Hotel room in Key West
4.92 out of 5 average rating, 26 reviews

Luxurious Stay | Snorkeling. Outdoor Pool

Poised on the islands famous harbor, The Marker Key West Resort is a fresh approach to luxury, seamlessly blending the elegance of classic Florida Keys resorts with an air of modern glamor. Attractions nearby: ✔Mallory Square, once anchorage of pirates ✔Snorkeling ✔Butterflies & exotic birds at the Butterfly and Nature Conservatory ✔Amazing views for the top of the Lighthouse Museum ✔Southernmost Point Buoy, lowest latitude land of contiguous North American states

Santa Maria Suites
4.88 out of 5 average rating, 26 reviews

Santa Maria Suites

Enjoy 910 sq. ft. of tropical modern living in this 2-bedroom, luxury bi-level suite. Upstairs bedrooms feature pillow-top queen beds, work desks, spacious closets, and spa-inspired separate bathrooms, one with a walk-in shower that includes a rainfall showerhead & the other with a full-sized bathtub. The suite includes a downstairs living area that comes with a comfortable queen-size sleeper sofa, guest powder room, and laundry area with both washer and dryer + pool view!

A well-lit King Room showcases a spacious layout with a plush king bed at the forefront. A cozy sitting area features a sofa and side table, with a desk and chair nearby. Natural light pours in through a window adorned with patterned curtains, revealing views of palm trees outside.
Hotel room in Key West
4.51 out of 5 average rating, 153 reviews

Coastal Comfort | Sunset-watching. Outdoor Pool

Indulge in coastal opulence at Hilton Garden Inn Key West, where luxury meets modernity amidst panoramic views, lavish accommodations, and impeccable service. Attractions nearby: ✔Southernmost Point Buoy, lowest latitude land of contiguous North American states ✔Mallory Square, once anchorage of pirates ✔Butterflies & exotic birds at the Butterfly and Nature Conservatory ✔Experience breathtaking vistas from the summit of the Lighthouse Museum ✔Snorkeling

Superhost
The living area features a Murphy bed within a dark wooden cabinet, a modern black sofa, and a wooden coffee table. A flat-screen television is positioned on a side cabinet. Natural light enters through sliding glass doors that lead to a private balcony.
Hotel room in Marathon
4.73 out of 5 average rating, 88 reviews

Knight's Key Suites Premium Apartment w/Kitchen

One-of-a-kind place accommodations located next to the 7-Mile Bridge in the heart of the Florida Keys. This room features one king, one queen, and one Murphy bed that can accommodate up to six people. full kitchen. Dear guest, we’re sorry to inform you that, due to unexpected circumstances beyond our control, the pool will be closed until Saturday 6/1/26. A significant leak was found and emergency repairs are necessary to fix the problem.

Superhost
Hotel room in Key West

Steps from the Beach + Free Shuttle & Pool

Experience the vibrant spirit of Cuba in the heart of Key West at Havana Cabana, a waterfront retreat full of charm and character. Classic cars, refreshing mojitos, and lively poolside music set the tone for a nostalgic escape inspired by Cuban art and culture. From the moment you arrive, vintage cars shine in the Florida sun while Flamenco rhythms and the scent of hand‑rolled cigars welcome you into an atmosphere that feels worlds away.

Guest favourite
Hotel room in Key West
5 out of 5 average rating, 34 reviews

Luxury King Studio – Come Hide at Key West Hotel

Welcome to The Key West Hotel—ideally located on Duval Street yet tucked away in a private oasis. Choose from charming rooms in a restored Victorian conch house or a modern poolside retreat, all surrounding a lush courtyard and sparkling pool. Guests can unwind at the exclusive Bali Bar, a tiki-style hideaway serving handcrafted island cocktails with live local music each night. It’s the perfect blend of relaxation and Key West energy.

Ella's Cottages - Key West Historic Inns
4.93 out of 5 average rating, 28 reviews

Ella's Cottages - Key West Historic Inns

Experience comfort and convenience in our king city single room. This inviting space features a plush king-size bed, private bathroom with premium amenities, and thoughtful touches like a hairdryer, hand steamer, and cozy robes. Enjoy modern comforts including free WiFi, air conditioning, a TV, refrigerator, and yoga mats for your relaxation. Pets are welcome, and a delicious breakfast is included to start your day right.

Superhost
Hotel room in Islamorada
5 out of 5 average rating, 3 reviews

Ideal Mix of Comfort & Value! Free Parking/ Pool

Escape to Amara Cay Resort in Islamorada, where breezy island flair meets boutique elegance. Enjoy private beach access, zero-entry pool with hammocks, and coastal-chic rooms with balconies. Explore kayaking, snorkeling, or hop a water taxi for dining across sister resorts—ideal for couples, families, or relaxed getaways.

Popular amenities for Key West hotels

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Quick stats about hotels in Key West

  • Total holiday rentals

    Explore 360 holiday rentals in Key West

  • Nightly prices starting at

    Key West holiday rentals start at £125 per night before taxes and fees

  • Verified guest reviews

    Over 3,950 verified reviews to help you choose

  • Family-friendly holiday rentals

    70 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 110 rentals that welcome pets

  • Holiday rentals with a pool

    360 properties feature pools

  • Rentals with dedicated workspaces

    160 properties have a dedicated workspace

  • Wifi availability

    360 of Key West holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Key West rentals

  • 4.6 Average rating

    Key West stays receive an average rating of 4.6 out of 5 from guests

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