
Guest house holiday rentals in Las Cruces
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Las Cruces
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Studio Casita 5 mins to Farmer's mkt/dogs welcome!
We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Relax in the ❤️ of Old Mesilla. Close to plaza.
Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Dream House - Seen On Visit Las Cruces YouTube
Casita de Sueños—“little house of dreams”—is an 800 sq ft adobe gem in historic Mesilla Park, Las Cruces. Built in 1938 as stables, it became a casita in the '50s, keeping its unique charm. Shaded by trees, it stays cool even on hot desert days. A peaceful retreat featured in Visit Las Cruces’ first episode of The Real New Mexico on YouTube! Please note if you’re not a fan of old charm, this may not be your kind of stay! The Airbnb has its original doors, windows, plumbing and old quirks!

Raven's House
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Desert Peaks Casita
This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Casita Florecita - Downtown Hacienda de Las Cruces (Little Flower House)
This casita with private entrance is on the grounds of an 1880's hacienda, steps away from downtown, parks, museums, live theatre, farmers market, restaurants & shopping. This charmer has original touches such as beams in the ceiling, large plank wood floors, adobe plaster walls, bedroom, living/dining combo, tiniest kitchen ever with all you need to cook up a meal, coffee and tea bar, and private bath. Outdoor: porch, patio, yard, pool and hot tub area (heated upon request)

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Casa Majik
A two bedroom casita with a kitchen. We have a full bath with tub and shower. Very quiet upscale neighborhood with all custom homes on 1 acre lots. Winding streets perfect for walking or biking. Less than 50 feet from the door of Casa Majik is a trail leading to "A" Mountain. Parking is for a maximum of two cars on the property. Restaurants and Memorial Hospital are 2 miles away.
Popular amenities for guest house rentals in Las Cruces
Family-friendly guest house rentals

Yucca Casita in Historic Mesilla

Cozy Casita De Mesilla (Mesilla Cottage)

Casita Florecita - Downtown Hacienda de Las Cruces (Little Flower House)

1 bed cute casita near NMSU, pet friendly

Quaint casita for 2

Cozy Casita with Patio

Raven's House

Desert Peaks Casita
Guest house rentals with a patio

Colorful & Cozy Las Cruces ‘Blue Moon Studio!’

Cozy King Suite "B" Near Downtown & Farmers Market

The Loft

Sunrise Casita
Guest house rentals with a washing machine and dryer

Ocotillo Casita in Historic Mesilla.

Hilltop Boutique Bungalow

Riverwood Casita

Cozy, Fenced in Casita in the Alameda District!

Casita Picaflor in the heart of Historic Downtown

1 king bd with big fenced back yard pets welcome

Vacation Home

Luxurious studio in the heart of Las Cruces
Quick stats about guest house rentals in Las Cruces

Total holiday rentals
Explore 40 holiday rentals in Las Cruces

Nightly prices starting at
Las Cruces holiday rentals start at £29 per night before taxes and fees

Verified guest reviews
Over 6,810 verified reviews to help you choose

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
40 of Las Cruces holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Las Cruces rentals

4.9 Average rating
Las Cruces stays are highly rated by guests – averaging 4.9 out of 5!
Destinations to explore
- Salt River Holiday rentals
- Tucson Holiday rentals
- El Paso Holiday rentals
- Northern New Mexico Holiday rentals
- Albuquerque Holiday rentals
- Ruidoso Holiday rentals
- Santa Fe Holiday rentals
- Ciudad Juárez Holiday rentals
- Chihuahua Holiday rentals
- Lubbock Holiday rentals
- Gilbert Holiday rentals
- Nogales Holiday rentals
- Townhouse rentals Las Cruces
- Rentals with a patio Las Cruces
- Rentals with outdoor seating Las Cruces
- Rentals with pools Las Cruces
- Rentals with a washing machine and dryer Las Cruces
- Rentals with a hot tub Las Cruces
- Rentals with a fireplace Las Cruces
- Rentals with a firepit Las Cruces
- Apartment rentals Las Cruces
- Private suite rentals Las Cruces
- Family-friendly rentals Las Cruces
- Pet-friendly rentals Las Cruces
- House rentals Las Cruces
- Rentals with breakfast Las Cruces
- Flat rentals Las Cruces
- Guest house rentals Doña Ana County
- Guest house rentals New Mexico
- Guest house rentals United States
- White Sands National Park
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- Western Playland
- El Paso Chihuahuas
- Dripping Springs Natural Area
- New Mexico Farm & Ranch Heritage Museum
- El Paso Museum of Art
- Parque Público Federal El Chamizal
- San Jacinto Plaza
- La Rodadora Espacio Interactivo
- El Paso Zoo
- Southwest University Park
- Sunland Park Racetrack & Casino
- Farmers And Crafts Market of Las Cruces




