
Holiday rentals in Los Santos Province
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Los Santos Province
Guests agree: these stays are highly rated for location, cleanliness and more.

Cottage + Pool + Wi-Fi + Air Con + Beach @Playalosdestiladeros
🌿 Charming rustic cabins in a French style, surrounded by nature in Playa Los Destiladores, Pedasí. ✔️A space to unwind, breathe, and enjoy the natural surroundings, just a short walk from the beach. It's not luxury; it's peace of mind and a connection with what's essential. The complex features a swimming pool and open areas that are perfect for relaxing with your whole family or group of friends. 🏕️Perfect for those seeking peace, nature and an authentic experience just a stone's throw from the sea🌊. Book now – we look forward to seeing you

Charming Cabaña on the beach
If you're looking for a place to relax and experience the magic of Cambutal with its lush jungle and stunning beaches, look no further. Nestled amongst the trees and overlooking one of the best swimming bays around, this rustic wooden cabaña has everything you need to make your stay unforgettable. Wake up to the sounds of the ocean on your doorstep, spend your days swimming in the warm ocean, or try other exciting activities, such as horse riding, hiking, yoga, surfing, diving and snorkelling.

Seaside Sanctuary • Steps to Surf • Fast Internet
Wake up to the rhythmic sounds of waves steps from your bed in this intimate beachfront paradise. Our charming one-bedroom home sits directly on Cambutal's pristine shoreline, offering ocean views and instant beach access. Relax on your private terrace with morning coffee as the sun rises, cook meals in the fully-equipped kitchen, and fall asleep to the soothing sounds of the surf. With Starlink internet, you can stay connected while experiencing the perfect blend of seclusion and convenience.

2nd floor Beach Apartment with Amazing Views!
Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.

Private Beach Studio · Sunset & Nature Views
Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Country House with Pool in La Enea de Guararé
Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Beach house in Pedasí
This brand new house in the village of Pedasí offers 2 bedrooms with private bathrooms and showers and a large living room with kitchen. In addition there is a swimming pool with wellness area with grill and a covered patio behind, perfect for resting or working. The house is a 5-minute drive to different beaches, including Playa El Arenal where you can take the boat to Isla Iguana.

Beach side stay at Casa Blanca
This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.

Arrue Coastal Escape 3BR / Pedasi
Welcome to our charming ocean view home! Located in a gated community, this modern and spacious residence features all the amenities needed for an unforgettable vacation. With three spacious bedrooms, it is the perfect place for groups of friends or families looking to enjoy a relaxing and fun-filled stay.

Luxury villa with ocean view near Playa Venao
Villa Bambú is a private tropical retreat where modern design meets nature. Wake up to open ocean views, unwind by your private pool, and enjoy the peace of an exclusive setting just minutes from Playa Venao. Perfect for disconnecting, recharging, or working remotely in a calm and inspiring environment.
Popular amenities for Los Santos Province holiday rentals
Other great holiday rentals in Los Santos Province

Comfortable flat in Las Tablas, quiet area

Drones Pedasi Ranch - Beach Pool Folk Fest Fishing

Luxury Cabin / Venao Beach

Casa Inito - Romantic Getaway

A Good Walk-Pedasi

Dos Mares Venao Village - Cabin

Victoria Apartment

Beautiful, fully self-contained apartment.
Destinations to explore
- Pet-friendly rentals Los Santos Province
- Bed and breakfasts Los Santos Province
- Rentals with pools Los Santos Province
- Rentals with beach access Los Santos Province
- Hotel rooms Los Santos Province
- Apartment rentals Los Santos Province
- Beachfront rentals Los Santos Province
- Boutique hotels Los Santos Province
- Rentals with a hot tub Los Santos Province
- Waterfront rentals Los Santos Province
- Rentals with an accessible-height bed Los Santos Province
- Villa rentals Los Santos Province
- Family-friendly rentals Los Santos Province
- Flat rentals Los Santos Province
- House rentals Los Santos Province
- Guest house rentals Los Santos Province





