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House holiday rentals in Panama Canal

Find and book unique houses on Airbnb

Top-rated house rentals in Panama Canal

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
5 out of 5 average rating, 9 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favourite
The image showcases the exterior of a two-story house, framed by lush greenery. Sunlight filters through trees, highlighting the white façade and green shutters. A covered area is visible at the front, along with a gated fence that adds security to the property.
Home in Panamá
4.89 out of 5 average rating, 100 reviews

3BR Home in Ancon Hill - Urban Oasis

Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Guest favourite
A modern exterior of a house is shown, featuring a white facade with two small, barred windows. A potted plant is positioned near the entrance, complemented by a secure front door. Soft light is emitted from two overhead fixtures, enhancing the welcoming appearance.
Home in Colón
4.92 out of 5 average rating, 13 reviews

Family style living in Colon, #2

Relax with the whole family at this peaceful place. This house is located on reverted Areas transferred back to Panamá, called Arco Iris, there’s plenty of space outside, the inside consist of a modern combination living room+kitchen, bathroom and a large bedroom with acomodación for 4 guest, the place is Airconditioned with Celling fans in the living room and bedroom. This is a second house constructed next to our first rental called, Family Style Living and close to the Panamá Canal Zone

Guest favourite
An outdoor space features a heated pool surrounded by light-colored tiles. A covered patio includes modern seating arrangements and a table, suitable for dining. Lush greenery is visible beyond the walls, with a glimpse of the sky above, providing a bright and open feel to the area.
Home in Vacamonte
5 out of 5 average rating, 33 reviews

The Hidden Gem

Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Guest favourite
The exterior of a modern house is shown, featuring a covered entrance and a driveway with a parked car. Lush green grass and tropical plants add a touch of greenery, complemented by a palm tree. Large windows offer light to the interior spaces.
Home in Panamá
4.88 out of 5 average rating, 24 reviews

Excellent and economical house in La Chorrera.

The house is completely private, has parking at the entrance, the master bedroom has a double bed, air conditioning and 65” smart TV and a fully private bathroom, a secondary bedroom with a double bed, air conditioning and 43” smart TV, a secondary bedroom with a twin bed, fan and 32” smart TV, and a shared bathroom. The living-dining room has a sofa, coffee table, TV table with a 32” smart TV, a 4-seat dining room, and a fully-equipped kitchen with a 16-foot refrigerator.

Superhost
Home in Panamá
4.73 out of 5 average rating, 26 reviews

Charming House in Casco Viejo

This recently renovated house is an absolute treasure. It blends history, charm, and modern comfort. Archeologists uncovered artifacts dating to the seventeenth century. Tastefully furnished with modern comforts and antiques, it's steps away from the Panama Canal Museum and in the heart of Casco Viejo, perfect for guests looking to immerse themselves in the cultural and culinary delights before retreating to the comfort and tranquility of their temporary home.

Top guest favourite
A spacious living and dining area is depicted, featuring a blue sectional sofa with yellow accent pillows. A glass dining table with yellow placemats and black chairs is shown. Natural light enters through windows, revealing a glimpse of greenery outside.
Home in Panama City
4.82 out of 5 average rating, 117 reviews

Spacious Panama House in the 'heart of the city'

You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Top guest favourite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 225 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favourite
A light and airy interior showcases a cozy sleeping area with a patterned quilt. A television is mounted on the wall opposite a decorative woven piece. Large windows present scenic views of the surrounding landscape, allowing natural light to illuminate the space.
Home in Panama City
4.79 out of 5 average rating, 119 reviews

Ocean-view loft near beach in Taboga

Cozy cottage with a private terrace and sweeping sea views—the beach, pier, and Panama City skyline. Central location: 5-min walk to beaches, bars, and restaurants; steps from the 1685 San Pedro Apóstol Church. 25-min ferry from Amador. Ideal for couples seeking privacy: greet the sunrise with coffee and unwind at sunset on the terrace. We are attentive hosts—happy to help with ferry times, reservations, and insider tips.

Superhost
Home in Brisas del Golf de Arraijan
4.79 out of 5 average rating, 33 reviews

Casa Esmeralda, Cozy for an Ideal Stay.

Casa Esmeralda is a spacious, comfortable, and cozy family home, ideal for families or groups looking for rest, privacy, and a great location. It features 3 bedrooms and 2 bathrooms, with bright, well-designed spaces created to make you feel at home from the very first moment. Located just 45 minutes from Panama City, in a quiet and easily accessible area, it’s perfect for combining relaxation and convenience.

Guest favourite
A private rooftop terrace offers expansive views of the ocean and skyline. Comfortable seating arrangements include a coffee table and lounge chairs beneath a shaded umbrella. Decorative plants enhance the outdoor space, while string lights provide a warm ambiance during evenings.
Home in Panamá
4.92 out of 5 average rating, 150 reviews

Exceptional three-story building with sea view

This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Top guest favourite
The kitchen area features a black dining table with four chairs, complementing a modern microwave and refrigerator. Warm decorative elements, including wall art and a candle, add character to the space, which is equipped with essential appliances and a clean countertop.
Home in Panamá
4.94 out of 5 average rating, 400 reviews

Private Studio 10 Min from the Airport!

Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

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