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House holiday rentals in Panama Canal

Find and book unique houses on Airbnb

Top-rated house rentals in Panama Canal

Guests agree: these houses are highly rated for location, cleanliness and more.

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Superhost
Home in Nuevo Emperador
4.5 out of 5 average rating, 6 reviews

Finca privada cerca de la ciudad | Uso exclusivo

Enjoy Finca Los Caobos exclusively, surrounded by nature and just a few minutes from the city Ideal for private family gatherings, intimate celebrations, and special get-togethers, the property features 3 bedrooms, spacious green areas, a pool, and peaceful spaces to relax and share meaningful moments Perfect for guests looking for privacy, comfort, and a relaxed atmosphere Private family gatherings may be considered with prior agreementAny additional activity must be disclosed before booking

Guest favourite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.94 out of 5 average rating, 18 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favourite
The image showcases the exterior of a two-story house, framed by lush greenery. Sunlight filters through trees, highlighting the white façade and green shutters. A covered area is visible at the front, along with a gated fence that adds security to the property.
Home in Panamá
4.9 out of 5 average rating, 109 reviews

3BR Home in Ancon Hill - Urban Oasis

Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Guest favourite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.96 out of 5 average rating, 84 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top guest favourite
Home in Vacamonte
5 out of 5 average rating, 12 reviews

casa sencilla con 2 habitaciones cerca de la playa

Relájate con tu familia en este alojamiento donde la tranquilidad se respira, la diversión te espera y no querrás salir de este paraiso. Aquí encontrarás un lugar sencillo y acogedor, dotado con los elementos básicos de una casa como sala, comedor, cosina, 2 habitaciones, 2 baños, aire acondicionado, nevera, lavadora, horno microhondas, sunduchera, cafetera, tv, wifi, piscinas, lago de kayak, (INCLUIDO EL INGRESO AL CLUB PARA 3 PERSONAS). Tenemos servicio de inDrive a cualquier destino.

Guest favourite
A vibrant water park is illustrated, featuring an array of colorful slides and a large structure with water cascading from the top. Bright green and yellow slides are visible, alongside purple and blue ones, all surrounded by palm trees against a clear blue sky.
Home in Panamá Oeste
4.94 out of 5 average rating, 108 reviews

Casa de Playa AX8 cerca de la ciudad!

Cozy and fully furnished home with hammocks to relax and a BBQ grill, perfect for sharing special moments. Enjoy access to a pool with waterslides, 🚣‍♂️ kayak-friendly lagoon, and ⚓ pirate ship for kids. Plus, play on the beach volleyball and sand soccer courts or stay active at the outdoor gym. 🎟️ Complimentary club access from Tuesday to Sunday, 8 a.m. - 6 p.m. (Closed on Mondays). Open daily on holidays. ✨ A space designed for you. Book now and enjoy the experience! ✨

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 219 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favourite
A charming facade displays three balcony areas adorned with greenery, enhancing the welcoming appearance of the building. The entrance features decorative signage alongside floral accents, while the muted color palette and architectural details of the windows contribute to the overall harmonious design.
Home in Panamá
4.88 out of 5 average rating, 33 reviews

Cómodo y lujoso apartamento

Disfruta de una experiencia con estilo en nuestro alojamiento en el Casco Antiguo, aprovecha la ubicación cercana a galerías de arte, restaurantes, artesanías,etc. Nuestra casa cuenta con tres habitaciones cada una con balcón, baño y closet, con una bonita cocina contemporánea equipada; una amplia sala y comedor , zona de labores. Cuentas con un area total de 326 mts² Toda la casa rodeada de balcónes donde puedes disfrutar de las vistas panorámicas.

Top guest favourite
A spacious living and dining area is depicted, featuring a blue sectional sofa with yellow accent pillows. A glass dining table with yellow placemats and black chairs is shown. Natural light enters through windows, revealing a glimpse of greenery outside.
Home in Panama City
4.83 out of 5 average rating, 124 reviews

Spacious Panama House in the 'heart of the city'

You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Top guest favourite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 232 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Top guest favourite
Home in Panamá
4.94 out of 5 average rating, 423 reviews

Estudio Privado a 10 Min del Aeropuerto !

Apartamento Entero a 10 MINUTOS del Aeropuerto! El apartamento está completamente amueblado incluyendo electrodomésticos y artículos de cocina , productos de aseo , sala comedor ,mesa de trabajo y demás. A sólo minutos caminando de la Estacion de METRO SAN ANTONIO y METROMALL. Ofrecemos Tours a San Blas -Tours a Monkey Island y el Canal de Panamá para que aproveches al maximo tu viaje. Nuestra casa es Tu casa en Panamá 🇵🇦

Guest favourite
A light and airy interior showcases a cozy sleeping area with a patterned quilt. A television is mounted on the wall opposite a decorative woven piece. Large windows present scenic views of the surrounding landscape, allowing natural light to illuminate the space.
Home in Panama City
4.8 out of 5 average rating, 128 reviews

Ocean-view loft near beach in Taboga

Cozy cottage with a private terrace and sweeping sea views—the beach, pier, and Panama City skyline. Central location: 5-min walk to beaches, bars, and restaurants; steps from the 1685 San Pedro Apóstol Church. 25-min ferry from Amador. Ideal for couples seeking privacy: greet the sunrise with coffee and unwind at sunset on the terrace. We are attentive hosts—happy to help with ferry times, reservations, and insider tips.

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