
Guest house holiday rentals in Pickens County
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Top-rated guest house rentals in Pickens County
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Your Charming Country Cottage
Whether you need a country getaway or a place to lay your head after a football game, our cottage in the foothills of upstate SC is the perfect spot for both. You’ll find us tucked away just outside the quaint little town of Six Mile, 10 miles north of Clemson University and in close proximity to 3 of the upstate's favorite lakes: Lake Keowee, Lake Jocassee and Lake Hartwell. Here you’ll enjoy the serenity of country life without feeling “too far out" or away from all the upstate has to offer.

Mountain Cabin on Creek at Jocassee Gorge.
Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

Fairy Forest Cabin with Hot Tub at Table Rock
Adventure and relaxation await you! Set half a mile off the road, surrounded by forest, you’ll feel like you’re far away from the demands of life as you soak in the hot tub. But you are right in the golden corner of SC, NC, GA mountains with the best of hiking, kayaking, cycling and dining nearby! Only 28 miles from Greenville, Clemson and Brevard NC with Table Rock State Park and Lakes Jocassee and Keowee a few minutes away. The perfect couple’s getaway! Use of SC State Park pass included.

Elfwing Carriage House
Bright & comfortable studio apartment located in a quiet family neighborhood in the country, yet minutes to town. We are an easy 15 minute drive to Clemson, less than 5 miles to SWU, 7 miles to Duke Energy. Smart location for the mountains & lakes, visiting colleges, and graduation. Tiger tailgate space available for an additional fee. Hikes, waterfalls, 12 Mile river & Lake Hartwell are nearby. Friendly dogs are fenced or in our home. Come enjoy neighborhood & country living at its finest!

La Bella Farm
Do you want to be close to Clemson(11 miles), Anderson(9 miles) OR Greenville(20miles)! Do you want to just get away from all of the noise and busy life. Then you have found your spot! This is a great detached garage apartment. Settled in the quiet country side of Pendleton SC. 1 bedroom&1 bathroom with an additional sofa bed&blow up mattress. Great view of nothing but beautiful land from the kitchen window yet minutes away from Death Valley,restaurants,shopping and 85.

Little Blue Cottage on the Jocassee Wilderness
Little Blue, named because it's surrounded by wild blueberries, is situated just steps from the Jocassee Wilderness Area listed by National Geographic as 9th out of “50 of the World's Last Great Places.” It's located on the property of Heart Ridge Retreat Center. Guests will have access to all the retreat center grounds which includes a well-stocked lake (bring your rod). It's also centrally located to many trails, waterfalls, state parks, and lakes.

Holly Hideaway! 10 Highway miles to Clemson U!
Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Cozy Greenville Guest Suite w/ Fire Pit
Relax in this clean, comfortable guest suite featuring a cozy bedroom, bright kitchenette, and private bathroom. Start your day with a fresh cup of coffee or unwind by the fire pit, surrounded by peaceful woods and quiet nature views. This private space is perfect for solo travelers or couples looking for a calm, convenient Greenville stay with all the essentials.

Gilded Frog Guesthouse. Rainfall Shower, King Bed
Welcome to the Gilded Frog Studio. Conveniently located between Greenville and Easley and only minutes from I85, we are positioned right in the heart of the growing Powdersville area. Whether you're visiting Greenville or looking for a local place to stay to catch a Clemson game, we offer the amenities you need to make your stay effortlessly enjoyable.

Breathtaking Romantic Rustic Style Loft - Clemson
Rustic styled 800 sq/ft full apartment above our barn-garage that sleeps 4. This amazing space is roomy and has separate parking and private entrance. Equipped with full kitchen, laundry, private deck and fire pit. We have adequate parking and pull thru drive for guests with boats. Pets are not permitted as some of our guests have allergies.

Nested Studio Woodscape
Escape to our modern rustic and refined small studio apartment, nestled in the country. Tucked away in the trees, it sleeps four, with one bathroom. Experience the perfect blend of serene seclusion and contemporary comfort in this charming retreat. Ideal for nature lovers and close to nearby attractions. Book now for an unforgettable getaway!

The Rabbit Hole near the Swamp Rabbit Trail
Welcome to The Rabbit Hole. Escape to our serene retreat, ideal for families and furry friends alike! Nestled just 3 minutes from the scenic Swamp Rabbit Trail and a quick 6- minute drive to downtown Travelers Rest, our cozy haven is the perfect home-based for exploring the beautiful upstate region, including nearby Furman University.
Popular amenities for guest house rentals in Pickens County
Family-friendly guest house rentals

Mountain Cabin on Creek at Jocassee Gorge.

Holly Hideaway! 10 Highway miles to Clemson U!

Fairy Forest Cabin with Hot Tub at Table Rock

Camper at Hickory Lodge and Guesthouse

La Bella Farm

Cozy Greenville Guest Suite w/ Fire Pit

Pickens Paradise

Gilded Frog Guesthouse. Rainfall Shower, King Bed
Guest house rentals with a patio

Cottage On Hemlock Hill

Adorable Cottage 2 mi. from Death Valley

Downtown Clemson Guest Suite!

Vacation Home Clemson and Lakes

Poolside Paradise Guesthouse
Guest house rentals with a washing machine and dryer

The Clemson Tiger Cub House

Gameday guest home near Death Valley

Clemson Carriage House - NEW!

Riggs Drive Gameday Getaway
Destinations to explore
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Tugaloo State Park
- Tallulah Gorge State Park
- Table Rock State Park
- Chimney Rock State Park
- Mountaintop Golf & Lake Club
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Maggie Valley Club
- Jump Off Rock
- Old Edwards Club
- Biltmore Forest County Club
- Tryon International Equestrian Center
- Wade Hampton Golf Club
- Vineyards for Biltmore Winery
- Woolworth Walk
- French Broad River Park
- Victoria Valley Vineyards
- Discovery Island
- Thomas Wolfe Memorial




