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Holiday rentals in San Antonio

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Home in Santiago
4.95 out of 5 average rating, 19 reviews

Comfortable house equipped near the center of Santiago.

Casa amplia, cómoda y totalmente equipada en una ubicación estratégica de Santiago.Perfecta para todo tipo de huéspedes: familias, viajeros de trabajo, estudiantes, personas que vienen a citas médicas o quienes buscan un espacio tranquilo y accesible. La casa está ubicada muy cerca del Hospital Dr. Chicho Fábrega, Clínica Norte, U.Latina, Oxford School, Comercios Supermercados, farmacia, ,restaurantes, y minutos de Santiago centro. Un lugar seguro para estadías cortas y de larga estancia.

Guest favourite
A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.
Home in Chitre
4.87 out of 5 average rating, 62 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Guest favourite
The house exterior features a warm peach-colored facade with a large white-framed window. Tropical palm trees and vibrant flowering shrubs border the front, providing a refreshing touch to the entrance.
Home in Chitre
4.82 out of 5 average rating, 74 reviews

NinaHouse, spacious and cool house in Chitré.

Casa solo para ti, ahora con tanque de agua!hasta 7 p, amplia y en una de las mejores zonas de Chitré, tranquila y familiar, acceso a la piscina del area social, parques y canchas, cerca de todo: supermercados, casino, bus; ven a Chitre y disfrutar de comidas típicas, artesanía; planifica tus paseos y visita las mejores playas: Pedasi, Venao, Isla Iguana, podrás trabajar desde NinaHouse contando con un rápido internet. Ahora contamos con aire acondicionado en la sala para tu confort.

Guest favourite
A wooden decoration is positioned on the bedspread, showcasing the words 'With Love Made in Panama.' The bed features a wooden headboard, complemented by a bedside lamp. Soft blankets and neutral-colored walls create a cozy sleeping environment.
Holiday home in Chitre
4.94 out of 5 average rating, 66 reviews

CASA EdditA ° Cozy house in Chitré

° CASA EDDITA ° Fully equipped house for your enjoyment. Spacious, cool, and cozy in one of the best-located residential areas of Chitré, close to everything: supermarkets, casinos, and a bus terminal. If you are thinking of touring Azuero, we suggest you stop at Casa Eddita, visit downtown Chitré, its handicrafts, cathedral and its variety of typical foods; from here you will be only 1:30 hr from the best beaches of Azuero in Pedasí (Playa Venao and Isla Iguana) Welcome!

A cozy corner is shown with a light-toned futon, paired with a small wooden table and two modern chairs. Natural light enters through two windows, complementing the warm wooden paneling on one wall.
Apartment in Panama City
4.63 out of 5 average rating, 32 reviews

Departamento 2E - BEST place in town.

Accessible apartment in the heart of Santiago, located 300m from the Central Bus Station and within walking distance of supermarkets and businesses. With good distribution of space, fresh and illuminated and with all basic services. The apartments provide a harmonious balance in the middle of the rush characteristic of the city, perfect for stays of families, friends, professionals, couples.

Superhost
A tranquil garden scene is depicted, featuring a winding pathway of smooth stones and pebbles. Surrounding areas are adorned with various flowering plants and a small pond, enhancing the peaceful ambiance. Lush greenery is visible in the background, contributing to the serene atmosphere.
Farm stay in Santa Fe
4.89 out of 5 average rating, 301 reviews

Santa Fe villa with a espectacular view

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Guest favourite
The two-story colonial house is showcased with a white facade and wooden accents. Decorative balconies with railings are present at the front, along with several potted plants adding color. The street is lined with other buildings, under a clear blue sky dotted with clouds.
Cottage in Parita District
4.8 out of 5 average rating, 44 reviews

Colonial House in Parita

Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Superhost
A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.
Flat in Santiago
4.88 out of 5 average rating, 8 reviews

d'rosas apartamentos 3PB

Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Guest favourite
A spacious living area is furnished with two orange sofas and a small black coffee table. Natural light filters through sheer curtains, illuminating the neutral-toned walls. A mounted television is visible, and a refrigerator is located in the background, suggesting a welcoming space for relaxation.
Home in Chitre
5 out of 5 average rating, 8 reviews

Centric and well equipped with capacity 10 people

Very central steps from supermarket, banks, hospitals. Great spaces, patio and all the comforts so you can enjoy your stay . A/C in all areas. Comfortable capacity in bed for 10 people. We are Pet Friendly. Parking for 2 cars under the roof and up to a third cart on the outside front of the house.

Superhost
A cozy living area is displayed with a blue sofa, a wooden coffee table, and a colorful area rug. The walls are painted in soft gray, and framed photographs are hung decoratively. A dining table for four is visible in the background, along with a fan for comfort.
Home in Chitre
4.69 out of 5 average rating, 35 reviews

Your Home Away From Home: Simple and Centrally Located

Enjoy the simplicity of this quiet and central accommodation. It has restaurants, supermarkets and nearby transportation terminal.

Superhost
A welcoming living area features a patterned sofa and a wooden coffee table, complemented by a small dining table with chairs. Natural light enters through an unseen window, illuminating the green patterned floor and walls. A decorative painting adds character to the space.
Home in Chitre
4.78 out of 5 average rating, 9 reviews

Central and pleasant house in Chitré!

Enjoy the easy access to everything from this perfectly located home, which will allow you to enjoy the activities in Chitré.

Guest favourite
A single-story house features an arched entry with decorative windows. The front porch is equipped with seating, surrounded by greenery. A paved driveway leads to the home, providing access for vehicles, while the roof offers ample shade.
Home in Santiago
4.92 out of 5 average rating, 12 reviews

Casa Nuevo San Juan

Easy access from the Panamericana. It is a central area has supermarket, pharmacy, restaurant, hospital availability.

Popular amenities for San Antonio holiday rentals