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Holiday rentals in Panama City

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Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living space features a sleek gray sofa and a circular coffee table, with a view of the city visible through large floor-to-ceiling windows. Two yellow chairs add a pop of color, enhancing the bright and airy atmosphere.
Apartment in Panamá
5 out of 5 average rating, 30 reviews

New Modern Condo 1BR Best Location! Rooftop Pool

➤ Centrally located in San Francisco, one of the best neighborhoods in Panamá City. Enjoy the high floor view from your private Balcony! FREE EARLY CHECK-IN (subject to availability) ★ Close to everything! Walk 5-10 mins to the Best Restaurants, Supermarkets and Multiplaza: the best Mall in Panamá Travel with the comfort of being in your home! in this new, high floor, modern and minimalist full apartment with top of the line appliances, which is great for personal/business or family enjoyment

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in Panama City
5 out of 5 average rating, 38 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost
Flat in Panamá
5 out of 5 average rating, 4 reviews

Incredible Renovated Apartment in Casco Viejo

Disfruta de un loft único en el corazón de Casco Viejo, ubicado en la emblemática Calle 4ta. Este apartamento ha sido totalmente remodelado, combinando a la perfección el encanto histórico de sus muros originales con un diseño moderno y elegante. La doble altura, la pared de piedra restaurada y los detalles artesanales en los pisos crean un ambiente acogedor y sofisticado. Su distribución abierta con sala, comedor y cocina integrada lo convierten en un espacio ideal para relajarse y compartir.

Guest favourite
A rooftop area features a refreshing pool surrounded by sleek decking, with city views in the background. Comfortable lounge chairs are positioned alongside the pool, inviting relaxation. The modern architecture is complemented by large windows that enhance the overall openness of the space.
Flat in Marbella
4.91 out of 5 average rating, 11 reviews

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking

Vive una experiencia única frente al mar en este lujoso y amplio apartamento, disfrutarás de una piscina con vista directa al océano, perfecta para relajarte. El apartamento está completamente equipado para una estancia inolvidable. Además, el edificio ofrece amenidades premium como sauna, gimnasio, billar pool, parqueadero y una espectacular terraza con vista 360° de la ciudad. Situado en una zona céntrica, estarás a pasos de los mejores restaurantes, tiendas y atracciones locales.

Guest favourite
A balcony is featured with two stylish chairs and a small side table. Lush treetops are visible below, with a vibrant urban skyline in the background. Natural light illuminates the space, creating a serene outdoor setting for relaxation.
Flat in Panamá
5 out of 5 average rating, 10 reviews

Cozy 1BR•Balcony Gym Rooftop Pool•Near Multiplaza

➤ Charming apartment, warmly decorated, balcony with enchanting views of lush treetops with the city's vibrant skyline in the distance. Minutes away from Multiplaza Mall . ★ Perfect for Remote Workers, 500 MB speed internet. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Shopping ➤ Urban Escape - Building Highlights: ★ Gym ★ 2 Co-Working Spaces ★ Pool on the Rooftop Terrace ➤ Located in San Francisco: Explore the City Easily | Uber-Friendly

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 7 reviews

Cosy apartment facing the sea.

This place is unique, it has its own style. Its location is strategic, it will be very easy to get there. It is located next to the Cinta Costera, near the metro station, Casco Antiguo, and all the tourist centers that Panama offers you. Come and enjoy this beautiful experience in one of the best buildings in Panama, which offers tranquility, entertainment, gastronomy, cocktails, history of Panama, breathtaking views, all within the same building. Visit us!

Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 148 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
A modern living area is showcased, featuring a light gray sofa positioned across from a flat-screen TV on a wooden console. Two abstract art pieces adorn the walls. Floor-to-ceiling windows offer views of the city skyline, enhancing natural light in the space.
Apartment in Panamá
4.95 out of 5 average rating, 130 reviews

Beautiful Apartment 3 guests

Moderno, elegante y cómodo departamento, cerca de todo! Restaurantes, farmacias, supermercados, canchas de padle, a pocos minutos del centro comercial Multiplaza. Totalmente amoblado, 1 recamara, 1 baño completo, walking closet, cocina, sala, área de desayunador, lavadora-secadora y balcón. Para su disfrute, piscina de agua salada en el último piso, gimnasio, espacio de co-working, incluye un espacio de estacionamiento con valet parking.

Top guest favourite
A modern living area is furnished with a dark sectional sofa adorned with colorful cushions. A coffee table rests on a patterned rug, and large windows provide a view of the ocean, allowing natural light to fill the space.
Flat in Marbella
4.93 out of 5 average rating, 58 reviews

Elegance and Comfort with Panoramic Sea View

Experience the luxurious oceanfront PH Yoo experience in this stylish apartment with king bed and floor-to-ceiling windows. Enjoy upscale amenities: pool, gym, squash, spa, and more. Prime location, close to tourist areas, restaurants, bars, and malls. Inside the building you can find gastronomic options with exclusive discounts and free valet parking. A modern, spacious and sophisticated space, ideal for an unforgettable getaway.

Top guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.97 out of 5 average rating, 118 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
Flat in Obarrio
4.94 out of 5 average rating, 17 reviews

Central and safe + rooftop with pool and views

Modern 1 bedroom apartment in a safe, strategic and super central area of Panama City. Just a 5-minute walk from the Metro (Via Argentina) and surrounded by restaurants, supermarkets, cafes, banks, and more. Ideal for digital nomads, business travellers, tourists or couples. Cozy and functional design, perfect for short or long stays. Enjoy comfort, style, and an unbeatable location for exploring or working in the city.

Guest favourite
Flat in Panamá
4.98 out of 5 average rating, 119 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Popular amenities for Panama City holiday rentals

Quick stats about holiday rentals in Panama City

  • Total holiday rentals

    Explore 4,740 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at £8 per night before taxes and fees

  • Verified guest reviews

    Over 114,280 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,480 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,680 rentals that welcome pets

  • Holiday rentals with a pool

    2,570 properties feature pools

  • Rentals with dedicated workspaces

    2,880 properties have a dedicated workspace

  • Wifi availability

    4,490 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill and Laptop-friendly workspace across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City