Some info has been automatically translated. Show original language

Holiday rentals in Panama City

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1
Superhost
A panoramic view of Panama City is captured during twilight, showcasing a skyline of modern high-rise buildings reflecting warm lights. The foreground includes a body of calm water and green spaces, while the illuminated structures highlight the city's vibrant architecture against the evening sky.
Apartment in San Francisco
4.92 out of 5 average rating, 12 reviews

Lovely 4 Bedroom Condo with Pool - Punta Pacifica

Your family will be close to everything when you stay at this centrally located place. Beautiful apartment 4 bedroom, 4 bathrooms, 2 Parking; with brand new Furnitures including Air Conditioners. Steps away from Super 99 & Riva Smith Supermarket, Hospital Punta Pacifica, Oceania, Ferrari, Wahaka Restaurant, JW Marriott Panama, Torres de las Americas and Multiplaza Mall with recognized brand designers as Gucci, Sara, Tommy Hilfiger, Carolina Herrera, Victoria Secret, Restaurants as Olive Garden

Guest favourite
A modern living area features a plush area rug underneath a glass coffee table, which displays decorative items and books. A flat-screen TV is mounted on a marble accent wall, and elegant dining furniture is visible in the background, creating a sophisticated and inviting atmosphere.
Flat in Bella Vista
4.86 out of 5 average rating, 43 reviews

Cozy Designer Stay at Yoo & Arts Panama

Experience an elegant, modern apartment with the and comfort that makes you feel right at home from the start. Located on the prestigious Avenida Balboa, in the iconic Yoo Panama & Arts Tower, this space blends designer style with unbeatable comfort. You'll be surrounded by top-rated restaurants, shopping centers, and just minutes from the historic charm of Casco Viejo — the city's most iconic neighborhood. Perfect for travelers who value great design, location, and an unforgettable stay. 🏙️✨

Guest favourite
A charming historic building features ornate white architecture with teal accents. Arched windows and balconies are visible on the upper levels, showcasing decorative wrought-iron railings. The entrance showcases double doors, inviting passersby to explore the structure's elegance.
Flat in San Felipe
4.85 out of 5 average rating, 168 reviews

Best location - Unique and charming loft

Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Guest favourite
A spacious master bedroom features a king-size bed with a soft grey comforter. Two elegant benches are positioned at the foot of the bed. A ceiling fan distributes air throughout the room, while light fixtures provide a warm glow. An open layout leads to a dressing area and private bathroom.
Flat in San Felipe
4.83 out of 5 average rating, 176 reviews

Lovely Spacious 3BR in Casco Viejo w/Balcony

Welcome to Casa Bandera, your retreat in the heart of Casco Viejo! Located in Panama's iconic Casco Antiguo, this elegant apartment combines the area's historic charm with modern comfort. It features three cozy bedrooms, each with a private bathroom; an in-house laundry center, a fully equipped kitchen, a living room, and a dining room, perfect for sharing in an exclusive setting. Perfect for up to six people. Enjoy an unforgettable stay in a cozy and fully equipped environment.

Guest favourite
A balcony area is visible, featuring a small dining table and several wooden chairs, overlooking expansive views of the ocean under a clear sky. A ceiling fan is mounted above, and potted plants add a touch of greenery to the space.
Flat in Bella Vista
4.99 out of 5 average rating, 77 reviews

Panama Canal City Luxury Condo ocean view balcony

Experience unparalleled luxury in our 2,045 sq ft apartment, located in one of Latin America’s tallest buildings. Perfect for business or vacation, offering prime access to Casco Viejo, top shopping malls, the banking district, restaurants, bars, and exclusive amenities. Just steps from the scenic coastal strip, our apartment boasts a spacious balcony with a unique view of the Pacific entrance to the Panama Canal—a breathtaking sight that’s truly one of a kind in the world.

Guest favourite
An infinity pool is featured on the rooftop, offering a panoramic view of the city skyline. Several white loungers are arranged along the pool's edge, complemented by sleek wooden decking. The surrounding buildings rise majestically, creating a modern urban backdrop.
Flat in San Francisco
4.79 out of 5 average rating, 67 reviews

Exclusivo apartamento/pool/coworking/view/ac/new

Disfruta de este lujoso apartamento, perfecto para quienes buscan comodidad y estilo, un espacio moderno y bien equipado, con todo lo necesario para una estancia inolvidable, en un exclusivo complex con amenidades exclusivas como piscina infinita, coworking, pet shower Situado en una ubicación céntrica, estarás a pocos pasos de restaurantes, tiendas y atracciones locales. Disfruta de la vibrante vida urbana y todo lo que la ciudad tiene para ofrecer.

Top guest favourite
Flat in San Felipe
4.97 out of 5 average rating, 105 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favourite
Flat in San Felipe
5 out of 5 average rating, 17 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Top guest favourite
Loft in San Felipe
5 out of 5 average rating, 19 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
A serene courtyard features a small pool surrounded by terracotta tiles and smooth wooden planks. Lush green plants are displayed throughout the space, enhancing the tranquil environment. The walls are adorned with original stonework, blending history with nature.
Home in San Felipe
4.76 out of 5 average rating, 109 reviews

Cozy house in Casco Viejo with private pool

Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the centre of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Its most outstanding features include a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Apartment in Santa Ana
4.93 out of 5 average rating, 30 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Guest favourite
A private balcony features woven chairs and a glass-topped table. Green ferns are visible hanging from the wall, while the tiled roof of nearby buildings adds a traditional touch to the view.
Loft in San Felipe
4.87 out of 5 average rating, 200 reviews

Corcho rooms #1 - queen rom with a balcony

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

Popular amenities for Panama City holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Panama City?

    Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.

  • What are the best things to do in Panama City with kids?

    Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.

  • What are some of the best things to do in Panama City?

    Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.

  • How is the weather in Panama City?

    Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.

  • What are the best places to visit in Panama City?

    Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.

  • What are some hiking trails in Panama City?

    Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.

  • What are some family activities we can do in Panama City?

    Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.

  • What are some of the best day trip ideas from Panama City?

    Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.

  • Are there any pet friendly accommodations available in Panama City?

    Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.

  • What are some local tips for visiting Panama City?

    When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.

  • What is Panama City known for?

    Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.

  • What are the best hidden gems to explore in Panama City?

    Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.

  • What are the best foods to try in Panama City?

    Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.

  • What should I bring for a trip to Panama City?

    Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.

  • What is the nightlife in Panama City like?

    Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.

  • What are the most popular events or festivals in Panama City?

    Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.

  • Are there family friendly vacation rentals in Panama City?

    Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.

  • When is the best time to visit Panama City?

    The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.

Quick stats about holiday rentals in Panama City

  • Total holiday rentals

    Explore 4,860 holiday rentals in Panama City

  • Verified guest reviews

    Over 124,900 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,530 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,800 rentals that welcome pets

  • Holiday rentals with a pool

    2,660 properties feature pools

  • Rentals with dedicated workspaces

    2,930 properties have a dedicated workspace

  • Wifi availability

    4,620 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Self check-in, Gym and BBQ grill across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama City