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Apartment holiday rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
A bright room features a spacious bed with light bedding against an arched wall. A small table holds a bowl of oranges. Open windows provide views of the outdoors, complementing the soothing ambiance created by warm lighting.
Flat
4.95 out of 5 average rating, 110 reviews

Apartments Plaza Mayor 35, 204 Studio Plaza

Apartamentos Plaza Mayor 35 is the ideal option for travelers interested in getting to know the Monumental Complex of Cáceres. We offer 11 unique apartments located in the Plaza Mayor de Cáceres, two steps from one of the most complete urban complexes of the Middle Ages in the world.The apartments are located in acozy manor house completely renovated with free Wi-Fi, air conditioning hot/cold, fully equipped kitchen, large living room with sofa bed, comfortable rooms and bathroom with shower.

Superhost
A historic stone building is framed by olive trees and illuminated pathways. The structure features multiple balconies and large windows, highlighting the significant architectural details. The surrounding garden includes well-maintained flower beds, creating a serene environment for guests.
Flat
4.88 out of 5 average rating, 8 reviews

Balcony of the Sierra- La Higuera

This accommodation has brick vaults, stonework lintels in the windows and direct access to the courtyard, representing the construction of the S. century. Palace that comes from Francisco Pizarro. In this accommodation you will find a kitchen-living room, a bedroom and a bathroom. It also has a porch with a terrace where you can appreciate the entire courtyard. You can swim in your pool. Perfect for staying with family or friends, and you can book more accommodations.

Top guest favourite
A spacious terrace can be seen featuring a table with blue glassware, surrounded by several white chairs. An umbrella provides shade, and the area is bathed in natural light. The backdrop includes rooftops and a clear blue sky.
Flat
5 out of 5 average rating, 29 reviews

Qazris Suites, Suite Altyin

Nuestro apartamento más luminoso y abierto, cuenta con un único gran espacio tipo estudio, equipado con aire acondicionado y todas las comodidades que buscas. En Altyn encontrarás una amplia estancia dividida en tres ambientes: zona de estar, cocina-comedor integrada con lavavajillas, horno, microondas y nevera grande y zona de dormitorio doble, cuenta con cuarto de baño completo con secador y una gran terraza-solarium en la azotea del edificio orientada al atardecer.

Top guest favourite
A spacious living and dining area features modern furniture and an artistic wall mural. A dining table is paired with several black chairs, while a comfortable seating arrangement includes a couch and a television. Natural light is allowed through window openings with wooden shutters.
Flat
4.99 out of 5 average rating, 148 reviews

Gran Apartamento Turistico Sir Galahad

Spacious and accessible accommodation, cozy, great views towards the Plaza Mayor and Old Town with all the necessary amenities for your comfort. Views towards the Wall, Arco de la Estrella, City Hall, a few meters away you can find Restaurants, Pharmacy, Pedestrian street of shops, Banks and Taxi Stop. Our apartment is located in the Monumental Zone. With prior authorization that we manage, it can be accessed for loading and unloading of luggage.

Top guest favourite
A modern living space features a pink sofa centered in the room, complemented by a glass coffee table. Below, a transparent floor reveals illuminated ancient Roman ruins. A dining table with chairs is positioned in the corner, and soft natural light filters through sheer curtains.
Flat
4.97 out of 5 average rating, 119 reviews

Proserpina- Central apartment with Roman ruins

Stay in a unique place! CMDreams are 4 tourist apartments located in the center of Merida, with private and covered parking. If something differentiates us, it is having preserved history to share it with our guests. You can walk on a glass floor and enjoy the Roman ruins that are visible and illuminated below. If you are looking for an unforgettable experience with the highest quality, book Apartamentos CMDreams.

Guest favourite
A wide-open landscape is depicted with rolling hills and patches of lush greenery. A large tree stands on the right, while distant mountains are visible under a cloudy sky. The scene conveys a serene and natural setting, ideal for nature lovers.
Flat
4.93 out of 5 average rating, 114 reviews

Charming studio with views

Studio apartment that was once an attic and now welcomes you as if it were a nest. It's small and simple but with handmade and original details that make it different. It's an ideal place for those looking to relax, for nature lovers and trails to walk quietly, without crowds. And it's especially a good place for birdwatching and the night sky.

Top guest favourite
A bright studio apartment is featured, showcasing a minimalist kitchen with a sink, stove, and storage drawers. A sofa bed is positioned across from a dining table with two chairs, offering a practical living space. Natural light fills the room through the window.
Flat
4.96 out of 5 average rating, 171 reviews

Cozy Centrally-Located Studio 2

Enjoy the simplicity of this quiet, bright, cozy and centrally located place. Come and feel at home, as if it were your own home! This studio is offered so that you can enjoy your stay in Mérida whether it is your first time in these charming lands or if you already know its charms.

Superhost
A shaded seating area is provided under a large canopy. Natural stone seating surrounds a round table, with lush greenery in the background. A rectangular pool is visible, framed by a well-maintained lawn and decorative flower pots along the fence.
Flat
5 out of 5 average rating, 5 reviews

Casa Rural El Miajón2 Near Trujillo

Apartment located in Campo Lugar (Cáceres) consists of 2 bedrooms, the first with a double bed and the second with two single beds, bathroom, kitchen and living room. It also has common areas such as a swimming pool, porch, garden and terrace. Registration Number TR-CC-00359

Guest favourite
A cozy bedroom features floral wallpaper with soft hues and a white metal bed adorned with a patterned blanket and yellow accent pillows. A white dressing table and mirror are positioned beside a window, letting in natural light, complemented by soft bedside lamps.
Flat
5 out of 5 average rating, 25 reviews

Rural Charm and Comfort, Casa Rural de la Vega 2

Welcome to Apartamentos de La Vega, a cozy family-run rural retreat, located in the picturesque village of Campo Lugar. These spacious, rustic-style apartments have been carefully decorated with charming details that will transport you to the area's natural beauty.

Guest favourite
A modern living area is presented with light wooden flooring and large windows allowing natural light. The space features a gray sofa, two accent chairs, and a round coffee table. A dining table with white chairs is positioned to enhance the functionality of the room.
Flat
4.93 out of 5 average rating, 14 reviews

La Pata Suites. Apartment 2

Enjoy a luxury experience in this centrally located accommodation, located 10 meters from Plaza Mayor. Opened in April 2025 after a comprehensive renovation. Personal information will be required from guests in accordance with current legislation.

Superhost
Flat
4.84 out of 5 average rating, 131 reviews

AP1- Modern studio in Plaza de la Constitución

Enjoy a luxurious experience in this modern one-room studio located in one of the most charming squares in Mérida where you can enjoy everything the city has to offer and with all the amenities.

Top guest favourite
The image features a historical square in Cáceres, showcasing a prominent stone tower and traditional buildings with terracotta roofs. A large yellow sign spelling 'Cáceres' stands in the foreground, while outdoor seating is visible, indicating a vibrant public space.
Flat
4.95 out of 5 average rating, 183 reviews

House for 5 people next to the main square

A spectacular, recently refurbished home offering 3 bedrooms in the heart of Cáceres and overlooking the city´s Old Town.

Popular amenities for Santa Cruz de la Sierra apartment rentals

  1. Airbnb
  2. Spain
  3. Extremadura
  4. Cáceres
  5. Santa Cruz de la Sierra
  6. Flat rentals