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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guest house in El Valle de Antón
4.99 out of 5 average rating, 116 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top guest favourite
An aerial view showcases a serene saltwater pool framed by lush greenery. Red umbrellas provide shade for outdoor seating areas. The open kitchen and dining space are visible, along with comfortable hammocks situated nearby, offering a relaxed atmosphere for guests.
Home in Costa Esmeralda
4.98 out of 5 average rating, 206 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.83 out of 5 average rating, 134 reviews

Cabaña de montaña con piscina privada

Disfruta de la paz y la naturaleza en esta acogedora y equipada cabaña, perfecta para desconectar y relajarte. Rodeado de bosques y con vistas espectaculares, aquí podrás respirar aire puro y contemplar las estrellas. ✔️ Ideal para parejas, familias o aventureros. ✔️ Senderos, ríos y miradores cercanos. ✔️ Espacios cómodos y equipados para tu confort. - Capacidad de 4 personas. - Posibilidad de tener 1 cama doble y 2 individuales o 4 camas individuales. - Descuento a partir de dos noches.

Superhost
A private swimming pool is set against a backdrop of vibrant sunset colors. Water features provide gentle splashes, and green plants outline the pool area. The modern house with large windows is visible in the background, blending with the natural surroundings.
Cottage in Panamá Oeste
4.82 out of 5 average rating, 190 reviews

Santa Fe de Lajas Chame, Panamá.

Santa Fe de Lajas en Chame, Provincia de Panamá oeste una casa vacacional, que te permite conectarte con la naturaleza y pasar ratos de esparcimiento solo o en familia. La casa tiene una capacidad para 10 personas. Cuenta con tres habitaciones, cada una con su baño privado. Cocina, sala, comedor, una habitacion para trabajar, piscina, terraza techadas, jardín al aire libre y área de BBQ. Servicios de Wifi y televisión. Accesibilidad a las playas del área, centros comerciales, montañas etc.

Superhost
A geodesic dome is nestled among lush greenery, surrounded by tall trees. The structure features a wooden deck that extends into the natural landscape, providing a seamless connection with the environment. Mist shrouds the distant hills, enhancing the tranquil setting.
Dome in Altos del Maria
4.93 out of 5 average rating, 100 reviews

Los Domos Panamá, Domo Fuego, Glamping en Altura.

Sumérgete en un oasis natural donde la conexión con la naturaleza se vuelve palpable. Rodeado de árboles y plantaciones de café, nuestro espacio ofrece una experiencia única para aquellos que buscan reconectarse con la naturaleza. Desde el canto de los pájaros hasta el aire puro que se respira, cada momento aquí es una invitación a la armonia. Contamos con un río privado de agua manantial totalmente fresca y Sumérgete en la experiencia nocturna con nuestro jacuzzi caliente al aire libre.

Guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 293 reviews

Cabaña Horizonte by Casa Amaya

Relájate en esta escapada única y tranquila en Cabaña Horizonte. Casa Amaya es un complejo de 6 cabañas ubicado en Chicá de Chame, clima fresco entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya Contamos con generador eléctrico en caso de apagón.

Guest favourite
Cabin in Altos del Maria
5 out of 5 average rating, 6 reviews

Fobos – Luxury 1-Bed Cabin with Jacuzzi

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Top guest favourite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 128 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.81 out of 5 average rating, 316 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Guest favourite
Cabin in Altos del Maria
4.83 out of 5 average rating, 127 reviews

Cabaña en Altos del María

Acogedora cabaña en Altos del María, ideal para parejas que buscan relajarse en un entorno de montaña. Disfruta de un clima frio, rodeado de naturaleza. Es petfriendly y está equipada con las comodidades esenciales: una habitación con cama Queen, sofá cama y colchón inflable, perfecta para hasta 4 personas. Cuenta con lavadora, parrilla, hamacas y garita para mayor seguridad. El ambiente está acondicionado para integrarse con la naturaleza. Estacionamiento para 3 carros.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 254 reviews

Armadillo Shelter & Garden. Valle de Anton

Es un alojamiento unico y especial que hemos diseñado para que experimentes el Valle de Anton de una forma mas consciente y natural. Es un RV o remolque remodelado, para hacerlo acogedor>funcional y cómodo >estilo tiny house. El espacio tiene una pequeña y completa cocina, agua caliente, wifi, café y te. Se encuentra rodeado por un lindo jardín. Con entrada independiente y un area para estacionar el auto. Es ideal para 1 o 2 personas.

Top guest favourite
The modern two-story cabin features large glass windows that offer expansive views of the surrounding greenery. A spacious deck with seating is visible, surrounded by lush vegetation and natural stone pathways leading up to the entrance.
Cabin in Panamá Oeste
4.9 out of 5 average rating, 192 reviews

Altos del María Cabaña La Loma de Styria

Relájate con toda la familia en este tranquilo lugar para quedarse. Es un lugar fantástico, fresco y agradable donde puedes hacer muchas actividades ecoturísticas, la mejor opción si deseas tener una de las mejores vistas que puedas imaginar. Ideal para parejas también. Contamos con 2 habitaciones 2do piso y 2 baños. Múltiples lugares para tomar bellísimas fotografías

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz