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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guest house in El Valle de Antón
4.99 out of 5 average rating, 119 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top guest favourite
Home in Costa Esmeralda
4.98 out of 5 average rating, 207 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favourite
A private pool area is featured, surrounded by lush greenery. A patio table with six chairs invites dining outdoors, while a lounge chair with colorful stripes offers a spot for relaxation. A large umbrella provides shade by the shimmering blue water.
Place to stay in San José
4.93 out of 5 average rating, 201 reviews

Casa en Punta Barco - Piscina y Naturaleza

Sol, brisa naturaleza y tranquilidad. Casa a 2 minutos del mar. Ven a relajarte con todas las comodidades. Contamos con: - 1 cuarto principal (cama king) con aire/ac, baño completo - 1 cuarto con cama queen, camarote, aire/ac y baño completo - 1 cuarto con cama queen, camarote, aire/ac y baño completo - 1 cuarto para personal de servicio: 1 camarote, abanico y baño completo. Piscina privada con cama para asolearse y una práctica banca y una mesa de comedor. Amplia terraza con 3 hamacas.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.83 out of 5 average rating, 139 reviews

Cabaña de montaña con piscina privada

Disfruta de la paz y la naturaleza en esta acogedora y equipada cabaña, perfecta para desconectar y relajarte. Rodeado de bosques y con vistas espectaculares, aquí podrás respirar aire puro y contemplar las estrellas. ✔️ Ideal para parejas, familias o aventureros. ✔️ Senderos, ríos y miradores cercanos. ✔️ Espacios cómodos y equipados para tu confort. - Capacidad de 4 personas. - Posibilidad de tener 1 cama doble y 2 individuales o 4 camas individuales. - Descuento a partir de dos noches.

Superhost
A geodesic dome is nestled among lush greenery, surrounded by tall trees. The structure features a wooden deck that extends into the natural landscape, providing a seamless connection with the environment. Mist shrouds the distant hills, enhancing the tranquil setting.
Dome in Altos del Maria
4.93 out of 5 average rating, 101 reviews

Los Domos Panamá, Domo Fuego, Glamping en Altura.

Sumérgete en un oasis natural donde la conexión con la naturaleza se vuelve palpable. Rodeado de árboles y plantaciones de café, nuestro espacio ofrece una experiencia única para aquellos que buscan reconectarse con la naturaleza. Desde el canto de los pájaros hasta el aire puro que se respira, cada momento aquí es una invitación a la armonia. Contamos con un río privado de agua manantial totalmente fresca y Sumérgete en la experiencia nocturna con nuestro jacuzzi caliente al aire libre.

Top guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 298 reviews

Cabaña Horizonte by Casa Amaya

Relájate en esta escapada única y tranquila en Cabaña Horizonte. Casa Amaya es un complejo de 6 cabañas ubicado en Chicá de Chame, clima fresco entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya Contamos con generador eléctrico en caso de apagón.

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.81 out of 5 average rating, 318 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Guest favourite
Cabin in Altos del Maria
4.83 out of 5 average rating, 132 reviews

Cabaña en Altos del María

Acogedora cabaña en Altos del María, ideal para parejas que buscan relajarse en un entorno de montaña. Disfruta de un clima frio, rodeado de naturaleza. Es petfriendly y está equipada con las comodidades esenciales: una habitación con cama Queen, sofá cama y colchón inflable, perfecta para hasta 4 personas. Cuenta con lavadora, parrilla, hamacas y garita para mayor seguridad. El ambiente está acondicionado para integrarse con la naturaleza. Estacionamiento para 3 carros.

Guest favourite
Home in Altos del Maria
4.75 out of 5 average rating, 140 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 260 reviews

Armadillo Shelter & Garden. Valle de Anton

Es un alojamiento unico y especial que hemos diseñado para que experimentes el Valle de Anton de una forma mas consciente y natural. Es un RV o remolque remodelado, para hacerlo acogedor>funcional y cómodo >estilo tiny house. El espacio tiene una pequeña y completa cocina, agua caliente, wifi, café y te. Se encuentra rodeado por un lindo jardín. Con entrada independiente y un area para estacionar el auto. Es ideal para 1 o 2 personas.

Guest favourite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.84 out of 5 average rating, 101 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Top guest favourite
The modern two-story cabin features large glass windows that offer expansive views of the surrounding greenery. A spacious deck with seating is visible, surrounded by lush vegetation and natural stone pathways leading up to the entrance.
Cabin in Panamá Oeste
4.9 out of 5 average rating, 195 reviews

Altos del María Cabaña La Loma de Styria

Relájate con toda la familia en este tranquilo lugar para quedarse. Es un lugar fantástico, fresco y agradable donde puedes hacer muchas actividades ecoturísticas, la mejor opción si deseas tener una de las mejores vistas que puedas imaginar. Ideal para parejas también. Contamos con 2 habitaciones 2do piso y 2 baños. Múltiples lugares para tomar bellísimas fotografías

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz