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Holiday rentals in Santa María

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness and more.

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Two dome structures are positioned on a terrace overlooking a lush green valley. A vibrant sunset casts warm colors across the sky, with scattered clouds creating depth. String lights are visible along the railing, enhancing the natural setting adorned with trees.
Dome in El Valle de Antón
4.88 out of 5 average rating, 104 reviews

A 5 min del Valle I Domo No. 7-Cafe gratis

🌄 Domo en El Valle – Naturaleza, paz y vistas increíbles • 🆕 Domo nuevo cama Queen WIFI • 🚿 Baño interno privado • 🌬️ Clima fresco de montaña todo el año • 🌿 Rodeado de vegetación • 🌄 Vistas increíbles • 🐶 1 mascota pequeña • ❄️ Nevera, microondas y cafetera (no hay cocina) • ☕Cortesía de bienvenida:Café, azúcar y crema en pequeñas cantidades para uso inicial de su estancia. • 🚗 A 5 min antes de El Valle (últimos dos minutos es de piedra, pasan carros pequeños) • 🕒 3 pm | 🕛 12 md

Top guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guest house in El Valle de Antón
4.99 out of 5 average rating, 125 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top guest favourite
Home in Costa Esmeralda
4.98 out of 5 average rating, 212 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favourite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo
4.96 out of 5 average rating, 28 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.84 out of 5 average rating, 143 reviews

Cabaña de montaña con piscina privada

Disfruta de la paz y la naturaleza en esta acogedora y equipada cabaña, perfecta para desconectar y relajarte. Rodeado de bosques y con vistas espectaculares, aquí podrás respirar aire puro y contemplar las estrellas. ✔️ Ideal para parejas, familias o aventureros. ✔️ Senderos, ríos y miradores cercanos. ✔️ Espacios cómodos y equipados para tu confort. - Capacidad de 4 personas. - Posibilidad de tener 1 cama doble y 2 individuales o 4 camas individuales. - Descuento a partir de dos noches.

Top guest favourite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 133 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Top guest favourite
Home in San Carlos
4.91 out of 5 average rating, 163 reviews

El Palmar, playa a 50 metros

Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras

Guest favourite
A covered patio area displays a mix of seating options, including two wicker chairs and a small glass-top table surrounded by greenery. A hammock hangs gracefully in the foreground, adding a touch of comfort to this relaxed outdoor setting.
Cottage in El Valle de Antón
4.98 out of 5 average rating, 163 reviews

Casa Campestre Los Macos, El Valle de Antón

🏡 Bienvenidos a Casa Campestre Los Macos, un refugio acogedor ubicado en el corazón verde de El Valle de Antón, dentro de un cráter volcánico extinto, el más grande habitado en el mundo. Es una experiencia de descanso total, en una zona segura y tranquila, ideal para amantes de la naturaleza, el silencio y el aire puro. Despertarás con el canto de los pájaros, disfrutarás una taza de café en el jardín y pasarás tardes familiares en una casa totalmente equipada.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 266 reviews

Armadillo Shelter & Garden. Valle de Anton

Es un alojamiento unico y especial que hemos diseñado para que experimentes el Valle de Anton de una forma mas consciente y natural. Es un RV o remolque remodelado, para hacerlo acogedor>funcional y cómodo >estilo tiny house. El espacio tiene una pequeña y completa cocina, agua caliente, wifi, café y te. Se encuentra rodeado por un lindo jardín. Con entrada independiente y un area para estacionar el auto. Es ideal para 1 o 2 personas.

Guest favourite
A private pool reflects the clear sky, with a view of the ocean in the distance. Lush greenery and colorful vegetation surround the pool area, providing a serene setting. The pool deck features a tiled surface, enhancing the outdoor experience.
Cottage in El Palmar
4.9 out of 5 average rating, 109 reviews

El Palmar Beach House - spectacular ocean view!

You will love my space because of the spectacular view of the ocean, mountains and all of its surroundings. The beach is only 100 meters or 5 minutes walking; 150 meters from the Pan-American Highway; only 10 kilometers from the supermarkets, shops and restaurants of Coronado; and 30-45 minutes from El Valle de Antón. It comes equipped with everything you need to spend a few relaxing days and enjoy the beach. Maximum capacity: 8 people.

Top guest favourite
A spacious living area is visible, adorned with natural light filtering through large glass doors that open to a lush outdoor setting. The seating arrangement includes a sofa and dining table surrounded by stylish chairs. A smart TV is mounted on the wall, complemented by decorative greenery.
Home in Santa Catalina
4.97 out of 5 average rating, 112 reviews

Casa Colibrí - modern house in the green

Casa Colibri is a beatiful, spacious home in the middle of nature and will make your stay in Santa Catalina perfect. It has a large terrace with a fantastic view into the green where you can relax and listen to the birds. The interior has a lot of natural light and stays cool during the day, in case you need to escape the tropical heat. It is the perfect place for a unique experience in this special town with your friends or family.

Top guest favourite
A bright dining area features a round wooden table surrounded by six turquoise chairs. Large windows allow natural light to fill the space, showcasing a cozy atmosphere. A wooden dresser and potted plants add touches of comfort. Arched openings lead to other rooms.
Home in El Valle de Antón
4.96 out of 5 average rating, 190 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Popular amenities for Santa María holiday rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María